江杰


Biography



江杰,理学博士,洪堡学者,硕士生导师。2012年博士毕业于兰州大学化学与化工学院,师从刘伟生教授。2012至2013年,在美国佐治亚州立大学分析化学所Gangli Wang教授课题组从事博士后研究。2014至2018年,获德国洪堡奖学金资助,在德国波恩大学药学所Christa E. Müller教授课题组从事化学生物学及药物化学研究。2019年入职山东大学任副研究员。


    研究方向:化学生物学

     1. 构建荧光探针用于研究生命体系分子事件的发生发展及疾病模型中的荧光成像;

    2. 用荧光的手段研究经典有机合成中的动力学问题;

 3. G-蛋白偶联受体荧光配体作为新型药物的研究。


    主要荣誉:

      2015年  德国洪堡科研奖学金

      2019年  山东大学未来学者

      2022年  山东大学化学与化工学院优秀班主任

      2022年  山东大学化学与化工学院青年教师授课比赛一等奖

      2023年  山东大学优秀班主任

      2023年  山东大学青年教师授课比赛一等奖

      2023年  “山东大学青年教学能手”称号


    科研项目:

       山东大学科研启动经费     主持

      山东大学青年学者未来计划(在研) 主持

      山东省自然科学基金青年项目(在研)   主持

      广东省自然科学基金青年项目 (在研)   主持

      深圳市自然基金面上项目(在研)   主持  


    主讲课程

    大学化学(本科生)专业英语(研究生)、绿色化学(本科生通识课程)实用美容化学(本科生通识课程


【硕士招生】2023年招收学术型硕士1名

【本科招生】现已指导并完成本科生科创实验项目5项,其中国家级项目1项,省级项目1项,院级项目3项。本科生作为第一作者发表论文2篇,参与作者发表论文3篇。热忱欢迎优秀本科生来实验室做科创实验和毕业设计!



    发表论文

   Work@SDU

23.  Li, Longfei; Yang, Shuo; Xu, Zhongyun; Li, Shengxiao; Jiang, Jie; Zhang, Yong-Qiang* Dinuclear Titanium(III)-Catalyzed Radical-Type Kinetic Resolution of Epoxides for Enantioselective Synthesis of cis-Glycidic Esters. J. Am. Chem. Soc. 2024, DOI: 10.1021/jacs.4c03346.



JACS-2.png

22.  Shen, Jian; Xu, Zhongyun; Yang, Shuo; Li, Shengxiao; Jiang, Jie;* Zhang, Yong-Qiang* Quaternary Stereocenters via Catalytic Enantioconvergent Allylation of Epoxides. J. Am. Chem. Soc. 2023145,  21122-21131.

JACS-1.png

21. Chu, Zi-Xuan (本科生); Song, Qi;Zhang, Yong-Qiang; Jiang, Jie* Recent Progress in the Development of Fluorescent Probes for Formaldehyde Detection and Imaging.  Coordination Chemistry Reviews 2023, Accepted.

1.png


20. Song, Qi.; Wang, Ning; Wang, Fangkun (本科生); Guo, Kaizhuo (本科生);Cui, Jiwei; Hao, Jingcheng; Zhang, Yong-qiang; Jiang, Jie * A highly selective NIR ratiometric fluorescent probe for in situ detection of metabolized hydrazine in living cells.  Sens. Actuators B Chem. 2023, 393, 134164.

WeChat图片编辑_20230620150520.jpg

19. Song, Qi.; Liu, Zhiqiang; Niu, Jie; Zheng, Bowen (本科生); Hao, Jingcheng; Jiang, Jie * A two-photon fluorescent probe for formaldehyde detection and regeneration in living cells. J. Mater. Chem. B 2023, 11, 4408-4415.【Hot paper】

1.png

18. Longfei Li, Wanjiao Chen, Zhongyun Xu, Jie Jiang, * Yong-Qiang Zhang* Enantioselective synthesis of (R)-Tiagabine via asymmetric hydrogen atom transfer protocol Synthesis 2023, ASAP. (DOI: 10.1055/a-2039-6180)

17.png

17.  Xu, Z.; Shen, J.; Li, L.; Chen, W.; Li, S.; Jiang, J.; Zhang, Y.-Q.*: (Salen)Titanium-catalyzed asymmetric hydrogen atom transfer for epoxides reduction. Angew. Chem. Int. Ed. 2022,  DOI: 10.1002/anie.202214111

20221116_10.1002_anie.202214111.jpg


16. Xueguang Liu, Wei Liu*, Zhenghua Ju, Jie Jiang, and Weisheng Liu*A hydrophilic mixed lanthanide metal–organic framework monitoring H2O in D2OInorg. Chem. 2022, 61, 19658-19662. (DOI: 10.1021/acs.inorgchem.2c03078)

16.png

15. Jingda Liu (本科生), Xinyu Ma, Qi Song, Junying Zang(本科生), Jingcheng Hao, Weisheng Liu, and Jie Jiang* Ratiometric fluorescent and colorimetric dual-modal sensing strategy for discrimination and detection of D2O from H2O. Chem. Comm. 2022, 58, 9262-9265. https://doi.org/10.1039/D2CC03530H

15.png

14. Jiang, J. *; Sun, H.; Hu, Y.; Lu, G.; Cui, J.; Hao, J.; “AIE + ESIPT” activity-based NIR Cu2+ sensor with dye participated binding strategy. Chem. Comm. 202157, 7685 - 7688.https://doi.org/10.1039/D1CC02233D

14.png




Work before SDU

13. Jiang, J.; Seel, C.; Temirak, A.; Namasivayam, V.; Arridu, A.; Schabikowski, J.; Baqi, Y.; Hinz, S.; Hockemeyer, J.; Müller, C. E: A2B Adenosine receptor antagonists with picomolar potency. J. Med. Chem. 2019, 62, 4032–4055.

12. Wang, T.; Wang, D.; Padelford, J. W.; Jiang, J.; Wang, G.:Near-Infrared Electrogenerated Chemiluminescence from Aqueous Soluble Lipoic Acid Au Nanoclusters. J. Am. Chem. Soc. 2016, 138, 6380−6383.

11. Jiang, J.; Conroy, C. V.; Kvetny, M. M.; Lake, G. J.; Padelford, J. W.; Ahuja, T.; Wang, G.: Oxidation at the Core-ligand Interface of Au Lipoic Acid Nanoclusters that Enhances the Near IR Luminescence. J. Phys. Chem. C 2014, 118, 20680 − 20687.

10. Conroy, C. V.; Jiang, J.; Ahuja, T.; Tang, Y.; Wang, G.: Enhancing Near IR Luminescence of Thiolate Au Nanoclusters by Theomo Treatments and Heterogeneous Subcellular Distributions. Nanoscale, 2014, 6, 7416 – 7423.

9. Liu, W.; Jiang, J.; Chen, C.; Tang, X.; Shi, J.; Li, Z.; Dou, W.; Yang, L.; Liu, W.: A Water-Soluble Colorimetric and Ratiometric Fluorescent Probe for Selective Imaging of Palladium Species in Living Cells. Inorg. Chem., 2014, 53, 12590 – 12594.

8. Jiang, H.; Jiang, J.; Cheng, J.; Dou, W.; Tang, X.; Yang, L.; Liu, W.; Bai, D.: A sensitive colorimetric and ratiometric fluorescent chemodosimeter for Hg2+ and its application for bioimaging. New J. Chem., 2014, 38, 109 – 114.

7. Jiang, H.; Luo, W.; Jiang, J.; Jin, X.; Dou, W.; Tang, X.; Yang, L.; Chen, C.; Ju, Z.; Yao, X.; Liu, W.: A resumable two-photon fluorescent chemodosimeter for Hg2+ in aqueous solution. Sensors and Actuators B, 2014, 204, 68 – 73. (IF = 4.097)

6. Jiang, J.; Liu, W.; Cheng, J.; Yang, L.; Jiang, H.; Liu, W.: A sensitive colorimetric and ratiometric fluorescent probe for mercury species in aqueous solution and living cells. Chem. Comm., 2012, 48, 8371 – 8373. (Top 10 most accessed articles in July, 2012)

5. Wang, Y.; Peng, X.; Shi, J.; Tang, X.; Jiang, J.; Liu, W.: Highly selective fluorescent chemosensor for Zn2+ derived from inorganic-organic hybrid magnetic core/shell Fe3O4@SiO2 nanoparticles. Nanoscale Res. Lett., 2012, 7, 86.

4. Jiang, J.; Jiang, H.; Liu, W.; Tang, X.; Zhou, X.; Liu, W.; Liu, R.: A colorimetric and ratiometric fluorescent probe for palladium. Org. Lett., 2011, 13, 4922 – 4925.

3. Jiang, J.; Jiang, H.; Tang, X.; Yang, L.; Dou, W.; Liu, W.; Fang, R.; Liu, W.: An efficient sensor for Zn2+ and Cu2+ based on different binding modes. Dalton Trans., 2011, 40, 6367 –6370.

2. Jiang, J.; Tang, X.; Dou, W.; Zhang, H.; Liu, W.; Wang, C.; Zheng, J.: Synthesis and characterization of the ligand based on benzoxazole and its transition metal complexes: DNA-binding and antitumor activity. J. Inorg. Biochem., 2010, 104, 583 – 591.

1. Tang, X.; Wang, W.; Dou, W.; Jiang, J.; Liu, W.; Qin, W.; Zhang, G.; Zhang, H.; Yu, K.; Zheng, L.: Olive-shaped chiral supramolecules: simultaneous self-assembly of heptameric lanthanum clusters and carbon dioxide fixation. Angew. Chem. Int. Ed., 2009, 48, 3499 – 3502.







Professional Experience

2014.07 -- 2017.04

德国波恩大学

2012.10 -- 2013.12

美国佐治亚州立大学

2018.12 -- Now

山东大学