Biography

康元环，博士，山东大学，海洋学院，助理研究员，硕士研究生导师，研究生招生专业：海洋科学专业（学术型）；生物与医药专业（专业型）。主要研究方向：（1）基于合成生物学、反向疫苗学等策略设计、研发新型疫苗；（2）合成生物学赋能新型微生态制剂的研制及应用；（3）病原菌致病机制、跨物种感染与传播分子机制研究等。主持国家自然科学基金面上项目、山东省重点研发计划重大项目、山东省自然科学基金项目等各级科研项目10余项，发表SCI论文70余篇，授权发明专利1件，制定地方标准1项。部分研究成果获吉林省科学技术进步奖二等奖1项，吉林省自然科学学术成果奖三等奖1项。担任Reviews in Aquaculture、Aquaculture、Food Research International、Virulence、International Journal of Biological Macromolecules、Fish & Shellfish Immunology、Frontiers in Microbiology、Journal of Fish Diseases等本学科领域十余种重要国际学术期刊的审稿人；担任教育部学位中心研究生学位论文评审专家、国家大学生创新创业项目评审专家。


指导学生情况：  

指导研究生获（硕士）研究生国家奖学金奖；  

指导研究生获校级优秀硕士学位论文；  

指导硕士研究生获评优秀毕业生；  

指导本科生获评校级优秀本科毕业论文；  

指导本科生主持完成多项国家级、省级大学生创新创业训练计划项目。


Professional Experience
  • 2021-08 — Now
    山东大学（威海）海洋学院
  • 2017-09 — 2021-07
    吉林农业大学
Publication
Research direction

1. 基于合成生物学、反向疫苗学等策略设计、研发新型疫苗

2. 合成生物学赋能新型微生态制剂的研制及应用

3. 病原菌致病机制、病原菌跨物种感染与传播分子机制研究

Papers

(1) PrkA negatively regulates the temperature tolerance and virulence of Aeromonas veronii .Food Science and Human Wellness .2024

(2) Improvement of non-specific immunity, intestinal health and microbiota of crucian carp (Carassius auratus) juvenile with dietary supplementation of Bacillus coagulans BC1 .Aquaculture .2024

(3) The evaluation of bacteriophage therapy in aquaculture: A systematic review and meta-analysis .Aquaculture .2024

(4) Gut microbiota and metabolites may play a crucial role in sea cucumber Apostichopus japonicus aestivation .Microorganisms .2023

(5) A systematic review, meta-analysis and meta-regression of the global prevalence of foodborne Vibrio spp. infection in fishes: A persistent public health concern .Marine Pollution Bulletin .2023

(6) Efficacy of a recombinant Lactobacillus plantarum Lp-pPG-Malt as an oral vaccine candidate against Aeromonas hydrophila infection in crucian carp .Fish & Shellfish Immunology .2023

(7) Oral vaccination with recombinant Lactobacillus casei with surface displayed OmpK fused to CTB as an adjuvant against Vibrio mimicus infection in Carassius auratus .Fish and ShellfishImmunology .2023

(8) Weissella confusa N17 derived from loach (Misgurnus anguillicaudatus) exhibits promising for further applications in loach aquaculture .Probiotics and Antimicrobial Proteins .2023

(9) Lc-pPG-612-OmpU-CTB: A promising oral vaccine for protecting Carassius auratus against Vibrio mimicus infection .Fish & Shellfish Immunology .2023

(10) Lp-pPG-611.1-LPS as an immune enhancer provides effective protection against Aeromonas veronii infection in Carassius auratus .Annals of the New York Academy of Sciences .2022

(11) Essential role of ascO for virulence of Aeromonas veronii and inducing apoptosis .Journal ofFish Diseases .2022

(12) Dietary supplementation with Weissella cibaria C-10 and Bacillus amyloliquefaciensT-5 enhance immunity against Aeromonas veronii infection in crucian carp (Carassiu auratus) .Microbial Pathogenesis .2022

(13) Comparative proteomic analysis reveals novel potential virulence factors of Aeromonas veronii .Annals of the New York Academy of Sciences .2021

Patens

1. 一种基因工程重组乳酸菌及在抗拟态弧菌感染方面的应用

Student Information
  • 赵慧婷  2024/12/05 Hits:[] Times
  • 吴宗秀  2023/09/23 Hits:[] Times
  • 陈风丽  2023/09/23 Hits:[] Times
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