• 2010/08/01-2013/09/13
  香港中文大学
  生物化学
• 2005/09/01-2008/07/01
  中国科学院广州生物医药与健康研究院
  生物化学与分子生物学
• 2000/09/01-2004/07/01
  山东大学
  生物科学

• 2013-12 — Now
  山大生命科学院
• 2010-01 — 2010-06
  香港大学李嘉诚医学院
• 2009-04 — 2009-11
  香港大学生命科学院
• 2008-09 — 2009-02
  中科院广州生物医药与健康研究院

1. 耳聋基因致病机制

2. 毛细胞发育的转录后调控机制

3. 机械-电转换调控机制

4. 静纤毛发育及维持机制

(1) RBM24 is required for mouse hair cell development through regulating pre-mRNA alternative splicing and mRNA stability .Journal of Cellular Physiology .2023 ,238 (5):1095-1110

(2) RBM24 is localized to stress granules in cells under various stress conditions .Biochemical and Biophysical Research Communications .2022 (608):96

(3) Disruption of the autism-related gene Pak1 causes stereocilia disorganization, hair cell loss, and deafness in mice .Journal of Genetics and Genomics .2021 ,48 (4):324

(4) Function and therapeutic potential of G protein-coupled receptors in epididymis .British Journal of Pharmacology .2020 ,177 (24):5489

(5) Endoplasmic Reticulum Stress in Hearing Loss. .Journalof Otorhinolaryngology, Hearing and Balance Medicine. .2018 ,1 (3)

(6) Identification of Binding Partners of Deafness-Related Protein PDZD7 .Neural Plasticity .2018

(7) Loss of CIB2 Causes Profound Hearing Loss and Abolishes Mechanoelectrical Transduction in Mice .Frontiers in Molecular Neuroscience .2017 ,10

(8) Assessing the effect of food mycotoxins on aromatase by using a cell-based system. .toxicology in vitro .2014

(9) Aflatoxin B1 augments the synthesis of corticotropin releasing hormone in JEG-3 placental cells. .Chem Biol Interact. .2015

(10) Effect of zeranol on expression of apoptotic and cell cycle proteins in murine placentae. .toxicology .2013

(11) Exposure to aflatoxin B1 in late gestation alters protein kinase C and apoptotic protein expression in murine placenta. .Reprod Toxicol. .2016

(12) Alternative splicing of inner-ear-expressed genes. .Front Med. .2016

1. 耳聋相关基因检测技术的研发, 2023/06/07-2027/12/31

2. 耳聋相关基因检测技术的研发, 2023/09/01-2027/12/31

3. 钙整合素结合蛋白CIB2在听觉中的功能研究, 2019/04/26-2022/06/30

4. F-BAR蛋白FCHSD1在小鼠听毛细胞中的功能 研究, 2015/01/01-2016/12/31

5. 利用基因敲除小鼠研究FCHSD1在听觉中的功能, 2014/08/15-2017/12/31

6. 利用基因敲除技术研究TRPN1在 斑马鱼听觉传导中的功能, 2014/01/01-2016/01/01