2020.04- 山东大学微生物技术研究院 副研究员
2016.08-2020.04 中国科学院青岛生物能源与过程研究所 博士后 助理研究员
2013.08-2016.07 中国科学院大学 生物化学 博士
2010.09-2013.07 南开大学 生物化学与分子生物学 硕士
2006.09-2010.07 鲁东大学 生物科学 学士
研究方向:
生物基化学品合成,微生物代谢调控
联系方式:
电话:0532-58632386
邮箱:liumin88(AT)sdu.edu.cn (将“(AT)”替换为“@”)
发表论文:
1. Min Liu#, Meitong Huo#, Changshui Liu, Likun Guo, Yamei Ding, Qingjun Ma, Qingsheng Qi, Mo Xian* and Guang Zhao*. Lysine acetylation of Escherichia coli lactate dehydrogenase regulates enzyme activity and lactate synthesis. Frontiers in Bioengineering and Biotechnology. 2022,10:966062.
2. Min Liu,#,∗ , Meitong Huo#, Likun Guo, Yingxin Fu, Mo Xian, Qingsheng Qi, Wei Liu*, Guang Zhao*. Lysine acetylation decreases enzyme activity and protein level of Escherichia coli lactate dehydrogenase. Engineering Microbiology,2022, 2:10045.
3. Min Liu#, Likun Guo#, Yingxin Fu, Meitong Huo, Qingsheng Qi, Guang Zhao*. Bacterial protein acetylation and its role in cellular physiology and metabolic regulation. Biotechnology Advances, 2021, 53:107842.
4. Min Liu, Yingxin Fu, Wenjie Gao, Mo Xian,* and Guang Zhao* Highly efficient biosynthesis of hypoxanthine in Escherichia coli and transcriptome-based analysis of the purine metabolism. ACS Synthetic Biology, 2020, 9(3):525-535.
5. Zhe Zhao, Mo Xian, Min Liu* and Guang Zhao*. Biochemical routes for uptake and conversion of xylose by microorganisms. Biotechnol Biofuels ,2020, 13:21.
6. Min Liu, Yamei Ding, Mo Xian* Guang Zhao*,Metabolic engineering of a xylose pathway for biotechnological production of glycolate in Escherichia coli. Microbial Cell Factories. 2018,17:51-62.
7. Yuhui Wang, Mo Xian, Xinjun Feng, Min Liu* Guang Zhao*. Biosynthesis of ethylene glycol from d-xylose in recombinant Escherichia coli. Bioengineered. 2018, 9(1): 233-241.
8. Min Liu, Yamei Ding, Hailin Chen, Zhe Zhao, Huizhou Liu, Mo Xian* and Guang Zhao*.Improving the production of acetyl-CoAderived chemicals in Escherichia coli BL21(DE3) through iclR and arcA deletion. BMC Microbiology. 2017,17(1):10-19.
9. Min Liu, Xueping Han, Mo Xian, Yamei Ding, Huizhou Liu*, Guang Zhao*. Development of a 3-hydroxypropionate resistant Escherichia coli strain. Bioengineered. 2016,7(1):21-27.
10. Min Liu, Lan Yao, Mo Xian, Yamei Ding, Huizhou Liu, Guang Zhao. Deletion of arcA increased the production of acetyl-CoA-derived chemicals in recombinant Escherichia coli. Biotechnology letter, 2016, 38(4): 97-101.
11. Min Liu, Xinjun Feng, Yamei Ding, Guang Zhao, Huizhou Liu, Mo Xian. Metabolic engineering of Escherichia coli to improve recombinant protein production. Applied Microbiology and Biotechnology, 2015, 99(24): 10367-10377.
主持项目:
1. 高碳原子经济性乙酰辅酶A衍生品底盘细胞的构建和调控机理研究,国家自然科学基金面上项目(22277068),54万元,2023.01-2026.12,主持。
2. 山东大学青年学者未来计划,山东大学,50万元,2020.09-2025.08,主持。
3. HN材料生物合成高效底盘细胞的设计与构建,中央JW科学技术委员会,100万元,2019.01-2020.12,主持。
4. 乙酰辅酶A衍生产品生物合成平台细胞的构建与调控机理研究,国家自然科学基金青年基金项目(21807101),27.5万元,2019.01-2021.12,主持。
5. 大肠杆菌高效转化木糖合成乙醇酸的研究,中国博士后面上基金一等资助项目(2016M600564),8.0万元,2016.07-2018.07,主持。
6. 木糖为底物高效合成乙醇酸的研究,青岛市博士后应用基础研究项目,5.0万元,2016.07-2018.07, 主持。
细菌代谢与调控团队