Guizheng Zou
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Professor  

Gender:Male

Alma Mater:南京大学

Education Level:With Certificate of Graduation for Doctorate Study

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长期从事分析化学专业的基础教学和科研工作, 致力于研发具有自主知识产权的电致化学发光试剂、分析方法和器件装置(详见同主页博客)。

2009年招收第一位硕士生, 开始独立开展科研工作; 目前课题组现已成功研发出一些列高单色性或低毒性电致化学发光物质(2011CdTe, 2014CdSe, 2016钙钛矿, 2017CuInS, 2019ZnAgInS, 2019Au纳米簇), 组装了多套基于曝光成像摄谱原理的电致化学发光光谱仪样机(2015)和PMT型双色电致化学发光分析仪(2017), 在国际上率先开展了纳米粒子在水相介质中的电化学发光性质及传感研究(2004)、光谱型电致化学发光传感分析技术研究(2016)、光谱分辨型电致化学发光多色分析和多组分分析研究(2016单色, 2017双色, 2018三色); 已在新型电致化学发光标记物、光谱型电致化学发光分析技术和装置研发等方面申请专利10余项, 其中6项发明专利和3项实用新型专利获授权, 初步构建成知识产权保护网; 相关成果与技术可为研发具有自主知识产权的全新电致化学发光检测装置、试剂盒及相关生化分析、临床诊断技术提供支持。

课题组致力于为ECL基础和应用研究培养能力全面的创新型人才, 现已完整培养8名硕士研究生, 其中两人获山东大学优秀硕士毕业论文, 一人获山东省优秀硕士论文。

研究成果及引用情况:

        http://www.researcherid.com/rid/B-6640-2013

        http://orcid.org/0000-0002-3295-3848


2019

1) Yang Liqiong, Zhang Bin, Fu Li, Fu Kena, Zou Guizheng,* Efficient and monochromatic electrochemiluminescence of aqueous-soluble Au nanoclusters via host–guest recognition, Angew. Chem. Int. Ed. 2019, 58, 6901-6905.

2) Fu Li, Zhang Bin, Long Xiaoyan, Fu Kena, Gao Xuwen, Zou Guizheng,* Promising electrochemiluminescence from CuInS2/ZnS Nanocrystals/Hydrazine via Internal Cu(I)/Cu(II) Couple Cycling, Anal. Chem. 2019, 91, 10221-10226.

3) Zhang Bin, Zhang Fang, Zhang Ping, Shen Dazhong, Gao Xuwen, Zou Guizheng,* Ultrasensitive electrochemiluminescent sensor for microRNA with multinary Zn–Ag–In–S/ZnS nanocrystals as tags, Anal. Chem. 2019, 91, 3754-3758.

4) Li Zhipeng, Wu Shuo,* Zhang Bin, Fu Li, Zou Guizheng,* Promising mercaptobenzoic acid-bridged charge transfer for electrochemiluminescence from CuInS2@ZnS nanocrystals via internal Cu+/Cu2+ couple cycling, J. Phy. Chem. Lett. 2019, 10, 5408-5413.


2018

1) Zhou Jie, Nie Lei, Zhang Bin, Zou Guizheng,* Spectrum-resolved triplex-color electrochemiluminescence multiplexing immunoassay with highly-passivated nanocrystals as tags, Anal. Chem.  2018, 90, 12361-12365

2) Long Xiaoyan, Zhang Fang, He Yupeng, Hou Shifeng, Zhang Bin, Zou Guizheng,* Promising anodic electrochemiluminescence of nontoxic core/shell CuInS2/ZnS nanocrystals in aqueous medium and its biosensing potential, Anal. Chem.  2018, 90, 3563-3569

3) He Yupeng, Zhang Fang, Zhang Bin, Zou, Guizheng,* Dichroic mirror-assisted electrochemiluminescent assay for simultaneously detecting wild-type and mutant p53 with photomultiplier tubes, Anal. Chem. 2018, 90, 5474-54805) 

4) Jin Yuchen, Kang Qi,* Guo Xinli, Zhang Bin, Shen Dazhong, Zou Guizheng,* Electrochemical-signal-amplification strategy for an electrochemiluminescence immunoassay with g-C3N4 as tags, Anal. Chem. 2018, 90, 12930-12936

5) He Yupeng, Yang Liqiong, Zhang Fang, Zhang Bin, Zou Guizheng,* Tunable electron-injection channels of heterostructured ZnSe@CdTe nanocrystals for surface-chemistry-involved eectrochemiluminescence, J. Phy. Chem. Lett. 2018, 9, 6089-6095

6) Zhang Fang, He Yupeng, Fu Kena, Fu Li, Zhang Bin, Wang Huaisheng, Zou Guizheng,* Dual-wavebands-resolved electrochemiluminescence multiplexing immunoassay with dichroic mirror assistant photomultiplier-tubes as detectors, Biosens. Bioelectron. 2018, 115, 77-82

7) He Yupeng, Hou Shifeng, Yang Liqiong, Zhang Fang, Zou Guizheng,* Adjustable electrochemiluminescence from highly passivated CdTe/CdS nanocrystals by simple surface decoration with counterions, Chem. Eur. J. 2018, 24, 9592-9597

8) Wu Yaqiang, Wang Peng, Zhu Xianglin, Zhang Qianqian, Wang Zeyan, Liu Yuanyuan, Zou Guizheng, Dai Ying, Whangbo Myung-Hwan, Huang Baibiao, Composite of CH3NH3PbI3 with reduced graphene oxide as a highly efficient and stable visible-light photocatalyst for hydrogen evolution in aqueous HI solution, Adv. Mater. 2018, 30, 1704342


2017

1) Tan Xiao, Zhang Bin, Zou Guizheng,* Electrochemistry and electrochemiluminescence of organometal halide perovskite nanocrystals in aqueous medium, J. Am. Chem. Soc. 2017, 139, 8772-8776

2) Zou Guizheng,* Tan Xiao, Long Xiaoyan, He, Yupeng, Miao Wujian,* Spectrum-resolved dual-color electrochemiluminescence immunoassay for simultaneous detection of two targets with nanocrystals as tags, Anal. Chem. 2017, 89, 13024-13029

2) Zhou Jie, He Yupeng, Zhang Bin, Sun Qiaoling, Zou Guizheng,* Spectrum-based and color-selective electrochemiluminescence immunoassay for determining human prostate specific antigen in near-infrared region, Talanta, 2017, 175, 117-121

3) Tan Xiao, Zhang Bin, Zhou Jie, Zou Guizheng,* Spectrum-based electrochemiluminescence immunoassay for selectively determining CA125 in greenish waveband, Chemelectrochem 2017, 4, 1714-1718

4) Long Xiaoyan, Tan Xiao, He Yupeng, Zou Guizheng,* Near-infrared electrochemiluminescence from non-toxic CuInS2 nanocrystals, J. Mater. Chem. C 2017, 5, 12393-12399

5) Huang Yan, Long Xiaoyan, Shen Dazhong, Zou Guizheng,* Zhang Bin, Wang Huaisheng, Hydrogen peroxide involved anodic charge transfer and electrochemiluminescence of all-inorganic halide perovskite CsPbBr3 nanocrystals in an aqueous medium, Inorg. Chem. 2017, 56, 10135-10138

6) Xue Jingjing, Zhang Ziyi, Zheng Fenfen, Xu Qin, Xu, Jinchun, Zou Guizheng, Li Lingling, Zhu Junjie,* Efficient solid-state electrochemiluminescence from high-quality perovskite quantum dot films, Anal. Chem. 2017, 89, 8212-8216

7) Shu Jiangnan, Han Zhili, Zheng Tianhua, Du Dexin, Zou Guizheng, Cui Hua,* Potential-resolved multicolor electrochemiluminescence of N-(4-Aminobutyl)-N-ethylisoluminol/tetra(4-carboxyphenyl)porphyrin/TiO2 nanoluminophores, Anal. Chem.  2017, 89, 12636-12640


2016

1) Zhang Xin, Zhang Bin, Miao Wujian, Zou Guizheng,* Molecular-counting-free and electrochemiluminescent single-molecule immunoassay with dual-sabilizers-capped CdSe nanocrystals as labels, Anal. Chem.  2016, 88, 5482-5488

2) Zhang Xin, Tan Xiao, Zhang Bin, Miao Wujian, Zou Guizheng,* Spectrum-based electrochemiluminescent immunoassay with ternary CdZnSe nanocrystals as labels, Anal. Chem. 2016, 88, 6947-6953

3) Huang Yan, Fang Mingxiang, Zou Guizheng,* Zhang Bin, Wang Huaisheng, Monochromatic and electrochemically switchable electrochemiluminescence of perovskite CsPbBr3 nanocrystals, Nanoscale 2016, 8,18734-18739

4) Yu Siqi, Zou Guizheng,* Wei Qin,* Ultrasensitive electrochemical immunosensor for quantitative detection of tumor specific growth factor by using Ag@CeO2 nanocomposite as labels, Talanta 2016, 156-157, 11-17

5) Ma Xiaolong, Zhang Xin, Guo Xinli, Kang Qi,* Shen Dazhong, Zou Guizheng,* Sensitive and selective determining ascorbic acid and activity of alkaline phosphatase based on electrochemiluminescence of dual-stabilizers-capped CdSe quantum dots in carbon nanotube-nafion composite,  Talanta 2016, 154, 175-182

6) Liu Suli, Zhang Qinghua, Zhang Long, Gu Lin, Zou Guizheng, Bao Jianchun, Dai Zhihui,* Electrochemiluminescence tuned by electron-hole recombination from symmetry-breaking in wurtzite ZnSe,  J. Am. Chem. Soc. 2016, 138, 1154-1157


2014

1) Liu Shufeng, Zhang Xin, Yu Yanmin, Zou Guizheng,* A monochromatic electrochemiluminescence sensing strategy for dopamine with dual-stabilizers-capped CdSe quantum dots as emitters, Anal. Chem. 2014, 86, 2784-2788

2) Liu Shufeng, Zhang Xin, Yu Yanmin, Zou Guizheng,* Bandgap engineered and high monochromatic electrochemiluminescence from dual-stabilizers-capped CdSe nanocrystals with practical application potential, Biosens. Bioelectron. 2014, 55, 203-208


2012

1) Liang Guodong, Liu Shufeng, Zou Guizheng,* Zhang Xiaoli, Ultrasensitive immunoassay based on anodic near-infrared electrochemiluminescence from dual-stabilizer-capped CdTe nanocrystals, Anal. Chem. 2012, 84, 10645-10649

2) Shen Liping, Sun Yuming, Li Jun, Chen Li, Li Lu, Zou Guizheng,* Zhang Xiaoli,* Jin Wenrui,* Heterogeneous electrochemiluminescence spectrometry of Ru(bpy)32+ for determination of trace DNA and its application in measurement of gene expression level, Talanta 2012, 89, 427-432

3) Peng Shasha, Zou Guizheng, Zhang Xiaoli,* Nanocomposite of electrochemically reduced graphene oxide and gold nanoparticles enhanced electrochemilunescence of peroxydisulfate and its immunosensing abililty towards human IgG, J. Electroanal. Chem. 2012, 686, 25-31

4) Chu Lin, Zou Guizheng, Zhang Xiaoli,* Electrogenerated chemiluminescence sensor for formaldehyde based on Ru(bpy)32+-doped silica nanoparticles modified Au electrode, Mater. Sci. Eng. C 2012, 32, 2169-2174


2011

1) Zou Guizheng,* Liang Guodong, Zhang Xiaoli, Strong anodic near-infrared electrochemiluminescence from CdTe quantum dots at low oxidation potentials, Chem. Commun. 2011, 47, 10115-10117

2) Sun Qixia, Zou Guizheng, Zhang Xiaoli,* Electrochemiluminescence DNA sensor based on hairpin structure DNA as recognition element and Ru(bpy)32+-doped silica nanoparticles as signal-producing compound, Electroanalysis 2011, 23, No.11, 2693-2698

3) Shen Liping, Li Jun, Li Lu, Zou Guizheng,* Zhang Xiaoli,* Jin Wenrui,* Ultrasensitive electrochemiluminescence method for determination of DNA using Ru(bpy)32+-coated magnetic submicrobeads wrapped with carbon nanotubes, Electrochem. Commun. 2011, 13, 1499-1501

4) Liang Guodong, Shen Liping, Zhang Xiaoli, Zou Guizheng,* One-pot synthesis of dual-stabilizer-capped CdTe nanocrystals with efficient near-infrared photoluminescence and electrochemiluminescence,  Eur. J. Inorg. Chem. 2011, 3726-3730

5) Liang Guodong, Shen Liping, Zou Guizheng,* Zhang Xiaoli, Efficient near-infrared electrochemiluminescence from CdTe nanocrystals with low triggering potential and ultrasensitive sensing ability, Chem. Eur. J. 2011, 17, 10213-10215

6) Li Lu, Li Mingyue, Sun Yuming, Li Jun, Sun Li, Zou Guizheng, Zhang Xiaoli,* Jin Wenrui,* Electrochemiluminescence resonance energy transfer between an emitter electrochemically generated by luminol as the donor and luminescent quantum dots as the acceptor and its biological application, Chem. Commun. 2011, 47, 8292-8294


2010

1) Li Mingyue, Sun Yuming, Chen Li, Li Lu, Zou Guizheng,* Zhang Xiaoli,* Jin Wenrui, Ultrasensitive eletrogenerated chemiluminescence immunoassay by magnetic nanobead amplification, Electroanalysis 2010, 22, 333-337


2009

1) Zou Guizheng, Highly conjugated water soluble CdSe quantum dots to multiwalled carbon nanotubes, Chin. Chem. Lett. 2009, 20, 356-357

2) Zhang Xiaoli, Li Linlin, Li Lu, Chen Jia, Zou Guizheng, Si Zhikun, Jin Wenrui,* Ultrasensitive electrochemical DNA assay based on counting of single magnetic nanobeads by a combination of DNA amplification and enzyme amplification, Anal. Chem. 2009, 81, 1826-1832

3) Li Jun, Zou Guizheng,* Hu Xiaofei, Zhang Xiaoli,* Electrochemistry of thiol-capped CdTe quantum dots and its sensing application, J. Electroanal. Chem. 2009, 625, 88-91

4) Chen Jia, Zou Guizheng,* Zhang Xiaoli,* Jin Wenrui, Ultrasensitive electrochemical immunoassay based on counting single magnetic nanobead by a combination of nanobead amplification and enzyme amplification, Electrochem. Commun. 2009, 11, 1457-1459


2008

1) Li Lu, Tian Xinzhe, Zou Guizheng, Shi Zhikun, Zhang Xiaoli,* Jin Wenrui,* Quantitative counting of single fluorescent molecules by combined electrochemical adsorption accumulation and total internal reflection fluorescence microscopy, Anal. Chem. 2008, 80, 3999-4006


2005

1) Zou Guizheng, Ju Huangxian,* Ding Weiping, Chen Hongyuan, Electrogenerated chemiluminescence of CdSe hollow spherical assemblies in aqueous system by immobilization in carbon paste, J. Electroanal. Chem. 2005, 579, 175-180


2004

1) Zou Guizheng, Ju Huangxian,* Electrogenerated chemiluminescence from a CdSe nanocrystal film and its sensing application in aqueous solution, Anal. Chem. 2004, 76, 6871-6876

2) Cui Hua, Zhang Zhifeng, Zou Guizheng, Lin Xiangqin, Potential-dependent electrochemiluminescence of luminol in alkaline solution at a gold electrode, J. Electroanal. Chem. 2004, 566, 305-313


2003

1) Cui Hua,* Zou Guizheng, Lin Xiangqin,* Electrochemiluminescence of luminol in alkaline solution at a paraffin-impregnated graphite electrode, Anal. Chem. 2003, 75, 324-331 

 


Educational Experience

2002.9 2005.7

  • 南京大学
  • 化学类其他专业
  • Doctor
  • With Certificate of Graduation for Doctorate Study

1999.9 2002.7

  • 中国科技大学
  • 化学类其他专业
  • Master
  • With Certificate of Graduation for Study as Master's Candidates

1995.9 1999.7

  • 聊城师范学院
  • 化学教育
  • Bachelor
  • 理学学士毕业

Work Experience

2007.1 Now
  • 山东大学化学与化工学院
  • 电分析、光分析和电致化学发光分析研究,承担化学类基础课教学工作
2005.7 2006.12
  • 山东大学环境研究院
  • 讲师
  • 纳米毒理研究
2011.3 2012.2
  • 美国南密西西比大学化学与生物化学系
  • 公派博士后

Social Affiliations

Research Focus

  • 生化分析及临床检验新技术
  • 电致化学发光检测装置及元器件研制
  • 电致化学发光