Research Group of Protein Structure and Drug Discovery at Shandong University Led by Professor Dalei Wu, our team was established in late 2016 under the State Key Laboratory of Microbial Technology at Shandong University. Over the years, we have grown into a rigorous, innovative, and cohesive research group comprising 1 professor, 1 associate researcher, 1 lecturer, 1 research assistant, 3 post...
山东大学微生物技术国家重点实验室教授、博导，先后入选山东省“青年泰山学者”、“省杰青基金”和教育部高层次青年人才项目（“新药创制”岗位），学术兼职包括中国药理学会专委会委员和《药学学报》青年编委等。课题组主要针对转录因子靶标蛋白从事结构与分子药理学研究和靶向分子发现，也从事生物合成相关酶的结构解析和催化机理研究，成果发表于Nature、Nature Chemical Biology、Nature Communications、PNAS、JACS等期刊...
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Transcription factors (TFs) specifically bind to DNA, recruit cofactor proteins and modulate target gene expression, render...
Hypoxia-inducible factors (HIFs) are α/β heterodimeric transcription factors modulating cellular responses to the low oxy...
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