上海交通大学硕士毕业生，研究领域为生物力学，2017年赴英国格拉斯哥大学攻读应用数学博士学位，2021年毕业后留任于格拉斯哥大学数学与统计学院，以副研究员身份从事交叉学科、特别是力学，生物学和计算机科学的交叉研究工作。2023年9月入职山东大学控制科学与工程学院任副研究员。在Dassault Systèmes有限元软件公司的Aabqus Living Heart项目中任技术顾问，获得苏格兰数学William Jack Prize奖。主持苏格兰青年基金项目，国家自然科学青基基金项目，山东省优秀青年科学基金项目（海外），山东省青年基金项目，山东省泰山青年学者，参与3英国工程与物理科学研究委员会青年和重点项目。

持续招收理工科硕士研究生，不限具体专业。

• 2017-10-01-2021-09-13
  英国格拉斯哥大学
  Postgraduate (Doctoral)
• 2014-09-01-2017-03-21
  上海交通大学
  With Certificate of Graduation for Study as Master's Candidates
• 2010-09-01-2014-06-26
  中国海洋大学
  University graduated

• 2023-09 — Now
  控制科学与工程学院山东大学
• 2021-09 — 2023-09
  数学与统计学院英国格拉斯哥大学

1. 使用机器学习发现软组织应变能量函数

2. 心脏运动图像追踪方法与深度学习结合

3. 数据驱动的本构模型参数

4. 基于机器学习的模型重构

5. 应力生长理论在心脏应用

6. 心肌组织主动收缩力学新模型

7. 生物软组织拉伸力学本构建模

(1)关德宝. Using LDDMM and a kinematic cardiac growth model to quantify growth and remodelling in rat hearts under PAH .Computers in Biology and Medicine .2024 ,171

(2) D.,Guan. An Updated Lagrangian Constrained Mixture Model of Pathological Cardiac Growth and Remodelling .Available at SSRN 4317882 .2023

(3) D.,Guan. A Novel Excitation–Contraction Model Based on Classical Hill Model .Computers in Biology and Medicine .2022 ,145 :105417

(4) D.,Guan. Using LDDMM and a kinematic cardiac growth model to quantify growth and remodelling in rat hearts under PAH .Computers in Biology and Medicine .2024 ,171 :108218

(5) D.,Guan. Effect of myofibre architecture on ventricular pump function by using a neonatal porcine heart model: From dt-mri to rule-based methods .Royal Society Open Science .2020 ,7 (4):191655

(6) D.,Guan. On the aic-based model reduction for the general holzapfel–ogden myocardial constitutive law .Biomechanics and Modeling in Mechanobiology .2019 ,18 (4):1213-1232

(7) D.,Guan. Comparison of the windkessel model and structured-tree model applied to prescribe outflow boundary conditions for a one-dimensional arterial tree model .Journal of biomechanics .2016 ,49 (9):1583-1592

(8) D.,Guan. Effects of dispersed fibres in myocardial mechanics, Part I: passive response .Mathematical Biosciences and Engineering .2022 ,19 (4):3972-3993

(9) D.,Guan. Effects of dispersed fibres in myocardial mechanics, Part II: active response .Mathematical Biosciences and Engineering .2022 ,19 (4):4101-4119

(10) D.,Guan. Modelling of fibre dispersion and its effects on cardiac mechanics from diastole to systole .Journal of Engineering Mathematics .2021 ,128 (1):1-24

(11) Y.,Mei. Association of cerebral infarction with vertebral arterial fenestration using non-Newtonian hemodynamic evaluation .Mathematical Biosciences and Engineering .2022 ,19 (7):7076-7090

(12) F.,Liang. Determinant factors for arterial hemodynamics in hypertension: Theoretical insights from a computational model-based study .Journal of biomechanical engineering .2018 ,140 (3)

(13) D.,Guan. Constitutive Modelling of Soft Biological Tissue from Ex Vivo to in Vivo: Myocardium as an Example .International Conference by Center for Mathematical Modeling and Data Science, Osaka University .2020 :3-14

(14) D.,Guan. Growth and Remodelling of Right Ventricle Under Pulmonary Arterial Hypertension .CMBE22, Milan, Italy, 27-29 Jun 2022 .2022

(15) D.,Guan. Effect of Myofibre Dispersion on Ventricular Pump Function .CMBE22, Milan, Italy, 27-29 Jun 2022 .2022

(16) D.,Guan. Effects of Myofibre Architecture on Biventricular Biomechanics: a Simulation Study .CMBE 2019, Sendai City, Japan, 10-12 Jun 2019 .2019 :248-251

1. （包干项目）心肌梗死后左心室结构功能重塑的生物力学机制探究, 2025-01-01-2027-12-31

2. 肺动脉高压下右心室结构功能演变的个体化生物力学建模及临床应用, 国家自然青年科学基金项目

3. 肺动脉高压下右心室的生长重构理论探究, 苏格兰青年基金项目

4. 先天性心脏病的数字孪生, 山东省优秀青年项目（海外）