• 2014-09 — 2018-06
  山东大学
  统计学
  理学学士学位
• 2018-09 — 2023-06
  山东大学
  流行病与卫生统计学
  医学博士学位

• 2023-07 — 2025-07
   北京大学 

主要研究方向为遗传统计中的因果推断方法研究及应用，包括工具变量、迁移学习、因果图结构学习、因果中介分析、选择偏倚、因果不变预测、多中心因果推断等等。共发表 SCI 文章 30 余篇，其中以第一作者/共同第一作者 11 篇 ，发表在Nature Communications、The American Journal of Human Genetics、Briefings in bioinformatics、PLoS Genetics等高水平遗传统计学、数学与计算生物学以及医学应用期刊上，同时为 eBiomedicine、Journal of the American Heart Association 等期刊的 审稿人。此外，本人曾获得中国博士后科学基金特别资助、面上资助、国资计划B档资助、北京大学博雅博士后资助，参与一项国家自然科学基金面上项目、一项北京市自然科学基金青年 项目，发明专利一项，一项科技成果被评为国际先进水平。

(1) 侯蕾.MR-EILLS: an invariance-based Mendelian randomization method integrating multiple heterogeneous GWAS summary datasets.自然通讯.2025,16 (1)

(2) Lei Hou, Hao Chen, Xiaohua Zhou.MR-EILLS: an invariance-based Mendelian randomization method integrating multiple heterogeneous GWAS summary datasets.Nature Communications.2025

(3) Lei Hou, Sijia Wu, Zhongshang Yuan, Fuzhong Xue, & Hongkai Li.TEMR: Trans-ethnic Mendelian Randomization Method using Large-scale GWAS Summary Datasets.The American Journal of Human Genetics.2025

(4) Lei Hou, Zhi Geng, Zhongshang Yuan, …, Feng Chen, Hongkai Li, & Fuzhong Xue..MRSL: a causal network pruning algorithm based on GWAS summary data.Briefings in bioinformatics.2024

(5) Yifan Yu, Lei Hou ( co-first author), …, Hongkai Li, & Fuzhong Xue.Causal associations between female reproductive behaviors and psychiatric disorders: a lifecourse Mendelian randomization study..BMC Psychiatry.2023

(6) Lei Hou, Yunxia Li, …, Hongkai Li, & Fuzhong Xue.The long-term mediation role of cytokines on the causal pathway from maternal gestational age to offspring eye diseases: Lifecourse-Network Mendelian randomization..International Immunopharmacology.2023

(7) Lei Hou, Yuanyuan Yu, …, Hongkai Li, & Fuzhong Xue..Causal mediation analysis with multiple causally non-ordered and ordered mediators based on summarized genetic data.Statistical Methods in Medical Research.2022

(8) Yuanyuan Yu, Lei Hou, (co-first author), …, Hongkai Li, & Fuzhong Xue. I.Impact of nonrandom selection mechanisms on the causal effect estimation for two-sample Mendelian randomization methods.PLoS Genetics.2022

(9) Hongkai Li, Lei Hou, (co-first author), …, Fuzhong Xue.Lipids, anthropometric measures, smoking and physical activity mediate the causal pathway from education to breast cancer in women: a Mendelian randomization study..Journal of Breast Cancer.2021

(10) Lei Hou, Hongkai Li, …, Fuzhong Xue.Exploring the causal pathway from bilirubin to CVD and diabetes in the UK biobank cohort study: observational findings and Mendelian randomization studies.Atherosclerosis.2021

(11) Lu Liu, Lei Hou (co-first author), …, Hongkai Li, & Fuzhong Xue..A novel method for controlling unobserved confounding using double confounders..BMC Medical Research Methodology.2020

(12) Lei Hou, Mingqing Xu, …, Hongkai Li, & Fuzhong Xue.Exploring the causal pathway from ischemic stroke to atrial fibrillation: a network Mendelian randomization study..Molecular medicine.2020

1. 一种基于因果网络不确定性推理的疾病预测预警系统

1. 基于多组学整合技术的糖尿病治疗新药物靶点 发现和旧药物重新定位研究, 北京市自然科学基金委员会, 青年项目，参与

2. 大数据背景下循证因果迁移学习的统计方法研究, 国家自然科学基金项目，面上项目，参与