Prof. Lei Zhang is a distinguished professor at the School of Public Health, Shandong University. He is the director and principal investigator of the Microbiome-X center at the National Institute of Health Data Science of China, as well as the principal investigator at the State Key Laboratory of Microbial Technology, Shandong University. He also serves as the president of the Shandong Institute of Industrial Technology for Healthy Sciences and Precision Medicine, and the deputy director of the Shandong Children's Microbiology Research Center at the Qilu Children’s Hospital of Shandong University. Prof. Zhang received his Ph.D. in Microbiology at the University of Bremen, Germany (2005). After his postdoctoral training at UCLA (2008). He was hired as Research Assistant Professor by UCLA since 2008 and principal investigator since 2010. Prof. Zhang focus on microbiome research. As the principal investigator of two research programs founded by TRDRP (Tobacco-Related Disease Research Program) and CBCRP (California Breast Cancer Research Program), he led multi-center studies that revealed the relationship between salivary microbiome and multiple cancers (Gut, 2012; Gastroenterology, 2010, and other 25 articles). At Shandong University, he initiated Shandong Microbiome Research Project, established a cross-regional 10,000+ cohort, and constructed a standardized biobank, mostly Type 2 Diabetes. He also built up the largest standardized microbiome data set in the National Omics Data Encyclopedia (NODE). Most importantly, he led the microbiome studies to decipher the "correlation→causality→intervention" in various diseases including T2D. In the past five years, his team have published 32 articles in Gut, 2021; mSystems, 2020; GPB, 2019; Microbiome, 2018, etc., and obtained 4 patents.
1. （包干项目）组学分析联合代谢模型探究阴道乳杆 菌与白色念珠菌之间的代谢竞争及其分子机制, 2025-01-01-2027-12-31
2. 肠道微生物调控Sirt1/Kiss1介导肥胖诱导的性早熟机制研究, 2023-08-24-2027-12-31
3. 国家自然科学基金委员会，面上项目，82172320，跨代遗传的DNA甲基化异常通过“微生物-肠-脑轴”参与孤独症的调控机制研究，2022/01-2025/12，54万元
4. 山东大学2021年度国家重点研发计划拟培育项目，健康人微生物组基线及特征解析，15万元
5. 山东大学杰出中青年学者（第一层次）学科建设经费，人体微生物组研究，2021/01-2025/12，200万元
6. 山东省科学技术厅，山东省泰山产业领军人才项目，tscy20190612，肠道微生态产业化研究与产品开发，2020/01-2023/12，200万元
7. 山东省中央引导地方科技发展资金项目，免疫诊断检测技术创新平台，YDZX20193700002067，2019-2021，300万元
8. 山东省科学技术厅，山东省重大科技创新工程项目，2018CXGC1219，性早熟儿童肠道菌群精准评估及肠道微生态个性化干预体系，2018/01-2020/12，100万元
9. 山东省科学技术厅，山东省重大科技创新工程项目，2018CXGC1218，脂代谢异常患者肠道菌群的变化特征和标志物及其精准干预方案，2018/01-2020/12，110万元
10. 山东省科学技术厅，山东省重点研发计划项目，2016YYSP009，以海洋生物资源为原料的高附加值医用食品制备及检测关键技术研究，2016/01-2018/12，100万元
11. 国家自然科学基金委员会，面上项目，31471202，非吸烟女性肺癌患者唾液基因标志物图谱与遗传和环境因素相关性的研究，2015/01-2018/12，85万元
