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所属单位：山东大学数学学院

发表刊物：Advanced Science

摘要：Mutual exclusivity of cancer driving mutations is a frequently observed phenomenon in the mutational landscape of cancer. The long tail of rare mutations complicates the discovery of mutually exclusive driver modules. The existing methods usually suffer from the problem that only few genes in some identified modules cover most of the cancer samples. To overcome this hurdle, an efficient method UniCovEx is presented via identifying mutually exclusive driver modules of balanced exclusive coverages. UniCovEx first searches for candidate driver modules with a strong topological relationship in ...

全部作者：Liu, J.,Li, Y.,Zhao, Y.

第一作者：Gao, B.

论文类型：期刊论文

通讯作者：Li*, G.,Su*, Z.

学科门类：理学

一级学科：数学

文献类型：J

卷号：6

期号：4

是否译文：否

发表时间：2018-12-01

收录刊物：SCI