李建华 (教授)

教授 博士生导师 硕士生导师

性别:男

学位:博士生

所在单位:口腔医学院

   

个人简介

李建华教授,博士生导师,山东大学口腔医学院生物材料研究室主任,口腔基础教研所副所长。

致力于材料与生物医学交叉领域研究,通过材料结构功能设计和表界面性质调控手段,从材料-生物界面角度探索理解材料与细胞、组织微环境之间的相互作用机制,具体研究应用于感染疾病控制、炎症免疫调控以及口腔组织工程等领域。

2019年入选山东大学齐鲁青年学者和山东省泰山学者青年专家计划。2023年山东省/山东大学优秀硕士学位论文指导教师、山东省学术研究生创新成果奖指导老师。

任《BMEMat》学术编辑/青年编委,中华口腔医学会口腔生物医学专业委员会青年委员。

教育工作经历:

2010年本科毕业,山东大学材料科学与工程学院;

2016年博士毕业,山东大学晶体材料国家重点实验室,师从刘宏教授;

2013-2014年,中科院北京纳米能源与系统研究所,博士联合培养;

2014-2016年,美国佐治亚理工学院生物医学工程系进行博士联合培养,师从Younan Xia教授;

2017至2018年,墨尔本大学化学与生物分子工程系,博士后研究,合作导师:澳大利亚科学院院士Frank Caruso教授;

2018年至2019年,香港科技大学化学与生物工程学院,博士后研究工作,合作导师:中国科学院院士唐本忠教授。



Recent Publications

[19]

Piezo-activated   Macrophage for Adoptive Cell Therapy of Bacterial Infection. 

Xiaoyi Liu,   Wenxiu Xu, Junkun Feng, Ying Wang, Kai Li, Yi Chen, Wenjun Wang, Weiwei Zhao,   Shaohua Ge*, Jianhua Li* 

Nature Communications, in publication

[18]

Metal-phenolic network biointerface-mediated cell   regulation for bone tissue regeneration. 

Ying Wang, Zhibang Li, Ruiqing Yu,   Yi Chen, Danyang Wang, Weiwei Zhao*, Shaohua Ge, Hong Liu, Jianhua Li*

Materials Today Bio, 2025, 30, 101400

[17]

Breaking   Piezoelectric Limits of Molecules for Biodegradable Implants. 

Hao, Jianhua*;   Malek, Nik, Kamaruddin, Wan, Li, Jianhua* 

BMEMat 2024, 2(2), e12087

[16]

A Multifunctional   Metal-Phenolic Nanocoating on Bone Implants for Enhanced Osteointegration via   Early Immunomodulation. 

J. Liu, Y. Shi, Y. Zhao, Y. Liu, X. Yang, K. Li, W.   Zhao, J. Han*, J. Li*, S. Ge* 

Adv Sci 2024, 2307269 IF15.1

[15]

Phenolic   Ligand–Metal Charge Transfer Induced Copper Nanozyme with Reactive Oxygen  Species-Scavenging Ability for Chronic Wound Healing. 

Y. Chen, X. Yang, K.   Li, J. Feng, X. Liu, Y. Li, K. Yang, J. Li*, S. Ge* 

ACS Nano 2024, 18, 9,   7024–7036 IF17.1

[14]

Intracellular   Delivery of Piezotronic-Dominated Nanocatalysis to Mimic Mitochondrial ROS   Generation for Powering Macrophage Immunotherapy 

J. Feng, X. Liu, K. Li, W.   Zhao, W. Wang, S. Ge*, H. Liu*, J. Li* 

Nano Energy 2024, 122,   109287 IF17.6

[13]

Microenvironment-Driven   Fenton Nanoreactor Enabled by Metal-Phenolic Encapsulation of Calcium   Peroxide for Effective Control of Dental Caries  

X. Yang, J. Shao, Y. Zhang, T. Wang, S. Ge   and J. Li*

Adv Healthcare Mater 2024, 13, 2303466 IF10.0

[12]

Green   Synthesis and Biosafety Assessment of MXene 

S. Zhang, L. Meng, Y. Hu, Z.   Yuan, J. Li*, H Liu* 

Small   2024, 20, 2308600 IF13.3

[11]

Surface-Confined   Piezocatalysis Inspired by ROS Generation of Mitochondria Respiratory Chain   for Ultrasound-Driven Noninvasive Elimination of Implant Infection. 

W. Xu, Y.   Yu, K. Li, L. Shen, X. Liu, Y. Chen, J. Feng, W. Wang, W. Zhao, J. Shao, B.   Ma, J. Wu, S. Ge*, H. Liu*, J. Li*   

ACS   Nano 2023, 17, 10, 9415–9428 IF17.1

[10]

Piezoelectric   nanostructured surface for ultrasound-driven immunoregulation to rescue   titanium implant infection. 

K. Li, W Xu, Y. Chen, X. Liu, L. Shen, J. Feng,   W. Zhao, W. Wang, J. Wu, B. Ma, S. Ge, H. Liu*, J. Li* 

Adv Funct Mater 2023,   33, 2214522 IF19.2

[9]

Janus   Porous Polylactic Acid Membranes with Versatile Metal-Phenolic Interface for   Biomimetic Periodontal Bone Regeneration. 

Y. Zhang, Y. Chen, T. Ding, Y.   Zhang, D. Yang, Y. Zhao, J. Liu, B. Ma, A. Bianco, S. Ge*, J. Li * 

npj Regenerative Medicine 2023, 8, 28 IF7.2

[8]

Stem   Cell Microencapsulation Maintains Stemness in Inflammatory Microenvironment.   

Y. Zhao, Y. Shi, H. Yang, M. Liu, L. Shen, S. Zhang, Y. Liu, J. Zhou, J. Lan,   J. Li*, S. Ge* 

Int   J Oral Sci 2022, 14, 48 IF14.9

[7]

Microencapsulation   of Ionic Liquid by Interfacial Self-assembly of Metal–Phenolic Network for   Efficient Gastric Absorption of Oral Drug Delivery. 

L. Shen, Y. Zhang, J.   Feng, W. Xu, Y. Chen, K. Li, X. Yang, Y. Zhao, S. Ge, J. Li*. 

ACS Appl. Mater. Interfaces, 2022,   14, 40, 45229–45239 IF9.6

[6]

Piezodeposition   of Metal Cocatalysts for Promoted Piezocatalytic Generation of Reactive Oxygen Species and Hydrogen in Water. 

W. Xu#, K. Li#, L. Shen, X. Liu, Y.   Chen, J. Feng, W. Zhao, L. Zhao, W. Zhou, W. Wang*, and J. Li* 

ChemCatChem.   2022, 14, e202200312 Selected as Cover Picture IF4.5

[5]

Metal   Phenolic Nanodressing of Porous Polymer Scaffolds for Enhanced Bone Regeneration via Interfacial Gating Growth Factor Release and Stem Cell Differentiation. 

Y. Zhang, K. Li, L. Shen, L. Yu, T. Ding, B. Ma, S. Ge, J. Li* 

ACS Appl. Mater. Interfaces 2022, 14, 1, 268–277 IF9.6

[4]

Editorial:   Rational Design and Preparation of Nanostructured Biomaterials. 

J. Li*, J. Qiu, S. Ge. 

Frontiers  in Chemistry 2022, 10:987447 IF5.5

[3]

Low   Frequency Hydromechanics-Driven Generation of Superoxide Radicals via Optimized   Piezotronic Effect for Water Disinfection, 

X. Liu, L. Shen, W.   Xu, W. Kang, D. Yang, J. Li*, S.   Ge*, H. Liu* 

Nano Energy 2021, 88, 106290 IF17.6

[2]

Metal-phenolic   network coatings for engineering bioactive interfaces. 

Zhang, L. Shen, Q.Z.   Zhong, J. Li*

Colloids  Surf B Biointerfaces 2021, 205,111851 IF5.8

[1]

Advancing   Versatile Ferroelectric Materials Toward Biomedical Applications. 

W. Wang, J. Li*, H. Liu*, S. Ge*. 

Advanced  Science 2021, 8, 2003074. IF15.1




Google Scholar:https://scholar.google.com/citations?user=sL4UZvkAAAAJ&hl=en

RG:https://www.researchgate.net/profile/Jianhua_Li7

教育经历

[1]   2010.9-2016.12

山东大学  |  材料物理与化学

[2]   2014.9-2016.9

Georgia Institute of Technology
博士联合培养

[3]   2013.8-2014.9

中科院纳米能源与系统研究所
博士联合培养

[4]   2006.9-2010.6

山东大学  |  材料物理

工作经历

[1]   2019.01-至今

山东大学  |  教授

[2]   2018.09-2019.03

香港科技大学  |  博士后

[3]   2017.03-2018.06

澳大利亚墨尔本大学  |  博士后