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Isoliensinine induces apoptosis in triple-negative human breast cancer cells through ROS generation and p38 MAPK/JNK activation.

Release time:2019-10-24|Hits:

Affiliation of Author(s):基础医学院

Journal:Sci Rep.

All the Authors:zhangxiyu,liuzhaojian,gongyaoqin,wangrong,liuqiao,shaochangshun

First Author:zhangxiyu

Document Code:lw-169470

Volume:5

Page Number:12579

Number of Words:5

Translation or Not:no

Date of Publication:2015-07-29

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Chemokine receptor CXCR2 is transactivated by p53 and induces p38-mediated cellular senescence in response to DNA damage.
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Replication stress induces micronuclei comprising of aggregated DNA double-strand breaks.

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