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Berberine induces oxidative DNA damage and impairs homologous recombination repair in ovarian cancer cells to confer increased sensitivity to PARP inhibition

Release time:2019-10-24|Hits:

Affiliation of Author(s):基础医学院

Journal:Cell Death & Disease

All the Authors:gongyaoqin,liuzhaojian,shaochangshun,liuqiao,zhangxiyu

First Author:houdong

Document Code:79E9ACE497E54EB18A8DAB3E94150B83

Volume: 8

Translation or Not:no

Date of Publication:2017-10-01

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Berberine induces senescence of human glioblastoma cells by downregulating the EGFR-MEK-ERK signaling pathway
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Chemokine receptor CXCR2 is transactivated by p53 and induces p38-mediated cellular senescence in response to DNA damage.

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