山东大学教师主页 Zhao Wang Structure-based design and optimization lead to the identification of novel dihydrothiopyrano[3,2-d]pyrimidine derivatives as potent HIV-1 inhibitors against drug-resistant variants Home

Zhao Wang

Associate Professor

Cheeloo College of Medicine School of Pharmaceutical Sciences

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Development of enhanced HIV-1 non-nucleoside reverse transcriptase inhibitors with improved resistance and pharmacokinetic profiles

Title of Paper:

Development of enhanced HIV-1 non-nucleoside reverse transcriptase inhibitors with improved resistance and pharmacokinetic profiles
Journal:

Science Advances
Note:

第一作者
Volume:

11
Issue:

22
Page Number:

eadt8916
Translation or Not:

No
Date of Publication:

2025-05
Included Journals:

SCI
Release Time:

2025-06-09

Next One: Escaping from flatland: multiparameter optimization leads to the discovery of novel tetrahydropyrido[4,3-d]pyrimidine derivatives as human immunodeficiency virus-1 non-nucleoside reverse transcriptase inhibitors with superior antiviral activities against non-nucleoside reverse transcriptase inhibitor-resistant variants and favorable drug-like profiles

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