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Education Background
  • 1991-09-01-1996-07-01
    山东医科大学
    Clinical Medicine
  • 2004-09-01-2008-12-30
    山东大学
    病理学与病理生理学
  • 1998-09-01-2001-07-01
    山东大学
    生理学
Work Experience
  • 2001-07 — Now
    山东大学医学院
  • 1996-07 — 1998-09
    山东医科大学生理教研室
Publication
Research direction
Papers

(1)刘建博. Death receptor 5 is required for intestinal stem cell activity during intestinal epithelial renewal at homoeostasis .Cell Death & Disease .2024 ,15 (1):27

(2) Chronic GPER activation prompted the proliferation of ileal stem cell in ovariectomized mice depending on Paneth cell-derived Wnt3 .CLINICAL SCIENCE .2023 ,137 (1):109

(3)薛冰. Activation of G protein coupled estrogen receptor prevents chemotherapy-induced intestinal mucositis by inhibiting the DNA damage in crypt cell in an extracellular signal-regulated kinase 1- and 2- dependent manner .Cell Death & Disease .2021 (11):1034

(4)王倩. Activation of the G Protein-Coupled Estrogen Receptor Prevented the Development of Acute Colitis by Protecting the Crypt Cell .《J Pharmacol Exp Ther.》 .2021 ,376 (2):281

(5)刘传勇. Oxytocin hyperpolarized cultured duodenum intrinsic primary afferent neurons by opening BKCa channels via IP3 pathway .Journal of Neurochemistry .2012 ,121 :516

(6)徐晓萌. Hydrogen sulfide downregulates colonic afferent sensitivity by a nitric oxide synthase-dependent mechanism in mice .Neurogastroenterology and Motility .2019 ,31 (1)

(7)李艳君. G protein-coupled estrogen receptor is involved in modulating colonic motor function via nitric oxide release in C57BL/6 female mice .Neurogastroenterology and Motility .2016 ,28 (3):432

(8)薛冰. Mast cells and the cyclooxygenase pathway mediate colonic afferent nerve sensitization in a murine colitis model .AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL .2013 ,174 (1-2):47

(9)刘传勇. Oxytocin down-regulates mesenteric afferent sensitivity via the enteric OTR/nNOS/NO/KATP pathway in rat .Neurogastroenterology and Motility .2015

(10)薛冰. Modulation of intestinal afferent nerve sensitivity to inflammatory mediators following systemic endotoxin in mice .Neurogastroenterol Motil .2015 ,27 (4):550

(11)薛冰. Afferent nerve sensitivity is decreased by an iNOS-dependent mechanism during indomethacin-induced inflammation in the murine jejunum in vitro .Neurogastroenterol Motil .2009 ,21 (3):322

(12)柴世权. Activation of G protein-coupled estrogen receptor protects intestine from ischemia/reperfusion injury in mice by protecting the crypt cell proliferation .CLINICAL SCIENCE .2019 ,133 (3):449

(13)刘传勇. Oxytocin down-regulates mesenteric afferent sensitivity via the enteric OTR/nNOS/NO/KATP pathway in rat .Neurogastroenterology and Motility .2015

(14)Liu Chuanyong. Oxytocin down-regulates mesenteric afferent sensitivity via the enteric OTR/nNOS/NO/KATP pathway in rat .Neurogastroenterology and Motility .2015

(15)薛冰. Afferent nerve sensitivity is decreased by an iNOS-dependent mechanism during indomethacin-induced inflammation in the murine jejunum in vitro .Neurogastroenterol Motil .2009 ,21 (3):322

(16)薛冰. G protein-coupled estrogen receptor is involved in modulating colonic motor function via nitric oxide release in C57BL/6 female mice .Neurogastroenterology and Motility .2016 ,28 (3):432

(17)薛冰. Modulation of intestinal afferent nerve sensitivity to inflammatory mediators following systemic endotoxin in mice .Neurogastroenterol Motil .2015 ,27 (4):550

(18)薛冰. Mast cells and the cyclooxygenase pathway mediate colonic afferent nerve sensitization in a murine colitis model .AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL .2013 ,174 (1-2):47

Research Projects

1. G蛋白偶联雌激素受体激动剂G-1在化疗性脱发中作用的研究, 2024-04-10-2026-10-31

2. 死亡受体5调节ATOH1泛素化降解促进结肠干细胞增殖和溃疡性结肠炎黏膜愈合的机制研究, 2022-09-07-2026-12-31

3. 外膜炎症诱导动脉粥样硬化病灶形成的机制研究, 2003-12-01-2006-12-30

4. miR-122对HBV感染及其相关肝癌的基因调控机制研究, 2009-01-01-2011-12-30

5. 类胰蛋白酶在感染后IBS内脏高敏感性发生过程中的作用及其机制研究, 2006-01-01-2008-12-01

6. 高迁移率族蛋白B1在糖尿病大鼠脑缺血再灌注损伤中的促炎作用研究, 2010-01-01-2012-12-31

7. 在体示踪益生菌治疗肠易激综合征的微生态动力学研究, 2013-08-15-2018-12-31

8. 肌间神经丛内硫化氢抑制胃运动的生理意义及其机制研究, 2010-01-01-2012-12-31

9. 半边莲抑制动脉平滑, 2004-01-01-2007-12-31

10. 雌激素膜受体GPER激活诱导潘氏细胞成熟在维持肠干细胞微环境中的作用及机制研究, 2017-08-17-2021-12-31

11. 潘氏细胞雌激素膜受体GPER激活对化疗性胃肠综合征的保护作用及其机制, 2017-01-01-2018-12-31

12. 蛋白酶活化受体-4(PAR4)对结肠炎后内脏高敏感的影响及其相关机制, 2010-06-01-2012-12-01

13. 肠神经系统G蛋白偶联雌激素受体GPER表达调控及其参与慢性传输型便秘的机制, 2016-10-29-2019-06-30

14. 半边莲生物碱抑制高血压大鼠平滑肌细胞增殖作用的实验研究, 2004-12-30-2007-12-30

15. AH神经元在缩宫素调节内脏敏感性中的作用及其机制, 2012-01-01-2014-12-31

Teaching Achievement
Student Information
  • 李新运  2025-10-15 Hits:[] Times
  • 王莹  2025-10-15 Hits:[] Times
  • 许润泽  2025-10-15 Hits:[] Times
  • 刘建博  2025-10-15 Hits:[] Times
  • 杨楚荷  2025-10-15 Hits:[] Times
  • 刘凯旋  2025-10-15 Hits:[] Times
  • 柴世权  2025-10-15 Hits:[] Times
  • 任义航  2025-10-15 Hits:[] Times
  • 李召  2025-10-15 Hits:[] Times
  • 时子茹  2025-10-15 Hits:[] Times
  • 高晓培  2025-10-15 Hits:[] Times
  • 朱珂  2025-10-15 Hits:[] Times
  • 王勇  2023-09-23 Hits:[] Times
  • 李佳  2023-09-23 Hits:[] Times
  • 时子茹  2023-09-23 Hits:[] Times
  • 王莹  2023-09-23 Hits:[] Times
  • 李新运  2023-09-23 Hits:[] Times
  • 许润泽  2020-08-07 Hits:[] Times
  • 刘建博  2020-03-20 Hits:[] Times
  • 李召  2019-04-18 Hits:[] Times
  • 刘凯旋  2019-04-18 Hits:[] Times
  • 王倩  2019-04-18 Hits:[] Times
  • 柴世权  2019-04-18 Hits:[] Times
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