• Name (Pinyin):
  YANGZHONGBAO
• E-Mail:
  zbyang@sdu.edu.cn
• Date of Employment:
  2012-04-23
• School/Department:
  生命科学学院
• Education Level:
  Postgraduate (Doctoral)
• Business Address:
  青岛校区生命科学学院N2座233房间
• Gender:
  Male
• Degree:
  博士
• Status:
  Employed
• Alma Mater:
  德国汉诺威大学
• Supervisor of Doctorate Candidates
• Supervisor of Master's Candidates

杨中宝

教授，博士生导师

电话：0532-58630898

E-mail: zbyang@sdu.edu.cn

个人简介

杨中宝，德国汉诺威大学自然科学博士，师从世界知名植物营养学家Walter J. Horst教授，2012年4月到山东大学生命科学学院工作。现为山东大学生命科学学院教授。主要从事植物营养逆境适应与分子调控的研究。研究成果相继发表到Nature Communications、 Plant Cell、PNAS、New Phytologist、EMBO Reports、Plant Physiology、Plant Journal、Plant, Cell & Environment等国际知名期刊上面，主持国家自然科学基金、山东省重点研发计划和自然科学基金等科研项目十多项。

主要研究方向

（1）  植物耐铝毒分子调控机制

土壤酸化（pH ≤ 5.5）是全球范围内严重威胁农业生产和粮食安全的重要因素之一，约占全球全球可耕地面积的50%以上。在我国，酸性土壤遍布14个省区，约占全国总耕地面积的1/5。气候变化以及农业生产中不良的耕作方式如化肥的滥施等，均增加了土壤的酸化面积并加剧了土壤的酸化程度。铝（Al）作为地壳中含量最丰富的金属元素，在酸性条件下以三价铝离子（Al³⁺）形态释放进入到土壤溶液中，通过抑制植物根系生长，进而对植物的生长发育造成严重影响，成为酸性土壤上植物生长的最主要限制因素之一。本课题组以拟南芥和大豆为材料，重点从分子水平围绕植物如何响应和传递铝胁迫信号，进而通过分子应答机制调控铝毒害胁迫开展研究。以期为从分子水平上阐明植物铝胁迫分子信号调控路径和耐铝分子机制，挖掘植物耐铝关键基因，利用现代生物技术手段改良植物营养遗传性状，培育适应酸性土壤生长的作物新品种提供科学理论依据。

（2）  养分吸收利用与大豆发育调控

土壤养分为植物的生长发育提供了所必需的无机盐和有机物，它们通过植物的根系被吸收并运输到植物体的各个部分，进而维持和保证植物的正常生长和发育。养分的缺乏和失衡极易造成植物的生长障碍和发育缺陷。大豆作为极其重要的油料和经济作物之一，其生长发育和产量受到各种环境因素的影响。本课题组利用实验室创建的突变体库，对大豆发育和产量性状与养分吸收利用的关系，以及分子调控机制开展研究。从养分分子设计层面，挖掘高产优质大豆优良性状控制关键基因，进而通过改良大豆遗传性状培育优异新品种。

（3）  大豆根瘤固氮分子调控机制

大豆是重要的粮食和油料作物，大豆根瘤菌能够通过固氮作用为大豆的生长发育提供氮素营养，如何让根瘤菌更好地发挥共生固氮作用，进而提升大豆产量，是目前科研人员正密切关注的科学问题之一。本课题组利用实验室创建的突变体库，结合正反向遗传学手段以及各种分子生物学手段，对根瘤形成和固氮的分子调控机制开展研究。为分子设计培育高效固氮的高产优质大豆品种提供科学依据。

招生招聘

博、硕士研究生

• 学术型：细胞生物学、植物学

• 专业型：生物与医药

博士后科研人员：常年招聘，随时可联系。

欢迎有志于植物营养分子生物学的优秀本科生、博、硕士研究生和博士后研究人员加入!

论文论著成果

1. Cao H, Cui R, Guo H, Xia Q, Zhang J, Liu W, Yang ZB* (2025) Ca²⁺-dependent cytoplasmic and nuclear phosphorylation of STOP1 by CPK21 and CPK23 confers ALMT1-dependent aluminum resistance. Nature Communications, 16, 5225

2. Cao H, Zhang M, Zhu X, Bai Z, Ma Y, Huang CF, Yang ZB* (2024) The RAE1-STOP1-GL2-RHD6 module regulates the ALMT1-dependent aluminum resistance in Arabidopsis. Nature Communications, 15, 6294

3. Wang P, Cao H, Quan S, Wang Y, Li M, Wei P, Zhang M, Wang H, Ma H, Li X, Yang ZB* (2023) Nitrate improves aluminium resistance through SLAH‐mediated citrate exudation from roots. Plant Cell & Environment, 46, 3518-3541

4. Wang P, Wan N, Horst WJ, Yang ZB* (2023) From stress to responses: aluminium-induced signalling in the root apex. Journal of Experimental Botany, 74, 1358-1371

5. Zhu X, Wang P, Bai Z, Herde M, Ma Y, Li N, Liu S, Huang CF, Cui R, Ma H, Zhang M, Wang H, Wei T, Quan T, Zhang W, Liu C, Zhang T, Yang ZB* (2022) Calmodulin-like protein CML24 interacts with CAMTA2 and WRKY46 to regulate ALMT1-dependent Al resistance in Arabidopsis thaliana. New Phytologist, 233 (6): 2471–2487

6. Li C, Liu G, Geng X, He C, Quan T, Hayashi KI, De Smet I, Robert HS, Ding Z, Yang ZB* (2021) Local regulation of auxin transport in root-apex transition zone mediates aluminium-induced Arabidopsis root-growth inhibition. Plant Journal, 108(1):55-66

7. Chen W, Yuan D, Shan M, Yang ZB, Liu C (2020) Single and combined effects of amino polystyrene and perfluorooctane sulfonate on hydrogen-producing thermophilic bacteria and the interaction mechanisms. Science of the Total Environment, 703:135015 

8.  Zhang Y, Zhang J, Guo J, Zhou F, Singh S, Xu X, Xie Q, Yang Z, Huang CF*. (2019) F-box protein RAE1 regulates the stability of the aluminum-resistance transcription factor STOP1 in Arabidopsis. Proc Natl Acad Sci U S A. 116(1):319-327

9. Yang ZB, Liu G, Liu J, Zhang B, Meng W, Müller B, Hayashi K, Zhang X, Zhao Z, Smet ID, Ding Z (2017) Synergistic action of auxin and cytokinin regulates aluminum-induced root-growth inhibition in Arabidopsis. EMBO Reports, 18(7):1213-1230

10. Geng X, Walter J, Golz J, Lee JE, Ding Z, Yang ZB* (2017) LEUNIG_HOMOLOG Transcriptional Co-repressor Mediates Aluminum Sensitivity through PECTIN METHYLESTERASE46-Modulated Root Cell Wall Pectin Methylesterification in Arabidopsis. Plant Journal, 90(3):491-504

11. Yang ZB, He C, Ma Y, Herde M, Ding Z* (2017) Jasmonic Acid Enhances Al-Induced Root Growth Inhibition. Plant Physiology, 173: 1420-1433

12. Zhang M, Yanqi Ma Y, Horst WJ, Yang ZB* (2016) Spatial-temporal analysis of polyethylene glycol-reduced aluminium accumulation and XET action in root tips of common bean (Phaseolus vulgaris L.). Annals of Botany (London) 118(1):1-9

13. Yang ZB*, Horst WJ (2015) Aluminum-Induced Inhibition of Root Growth: Roles of Cell Wall Assembly, Structure, and Function. In S.K. Panda, F. Balusˇka (eds.), “Aluminum Stress Adaptation in Plants, Signaling and Communication in Plants”, Springer, Switzerland, pp253-274

14. Yang ZB, Geng X, He C, Zhang F, Wang R, Horst WJ, Ding Z (2014) TAA1-regulated local auxin biosynthesis in the root-apex transition zone mediates the aluminum-induced inhibition of root growth in Arabidopsis. The Plant Cell, 2014, 26(7):2889-2904

15. Yang ZB, Eticha D, Führs H, Heintz D, Ayoub D, Van Dorsselaer A, Schlingmann B, Rao IM, Braun HP, Horst WJ* (2013) Proteomic and phosphoproteomic analysis of polyethylene glycol-induced osmotic stress in root tips of common bean (Phaseolus vulgaris L.). Journal of Experimental Botany 64(18): 5569-5586

16. Yang ZB, Eticha D, Albacete A, Rao IM, Roitsch T, Horst WJ* (2012) Physiological and molecular analysis of the interaction between aluminium toxicity and drought stress in common bean (Phaseolus vulgaris). Journal of Experimental Botany, 63(8):3109-3125

17. Yang ZB, Eticha D, Rao IM, Rotter B, Horst WJ* (2011) Physiological and molecular analysis of polyethylene glycol-induced reduction of aluminium accumulation in the root tips of common bean (Phaseolus vulgaris). New Phytologist, 192(1): 99-113

18. Yang ZB, Eticha D, Rao IM, Horst WJ* (2010) Alteration of cell-wall porosity is involved in osmotic stress-induced enhancement of aluminium resistance in Phaseolus vulgaris L. Journal of Experimental Botany, 61(12): 3245-3258

19. Eticha D, Zahn M, Bremer M, Yang Z, Rangel AF, Rao IM, Horst WJ* (2010) Transcriptomic analysis reveals differential gene expression in response to aluminium in common bean (Phaseolus vulgaris) genotypes. Annals of Botany (London), 105(7): 1119-1128

20. Yang ZB, Rao IM, Horst WJ* (2013) Interaction of aluminium and drought stress on root growth and crop yield on acid soils. Plant and Soil, 372(1-2): 3-25

21.Yang ZB, You JF, Xu MY, Yang ZM* (2009) Interaction between aluminum toxicity and manganese toxicity in soybean (Glycine max). Plant and Soil, 319(1-2)：277-289