医学博士，副主任医师，山东大学副教授，学术和专业型硕士研究生导师。

【临床医疗】从事临床工作17年，擅长强迫障碍、抑郁障碍、焦虑障碍、睡眠障碍等临床常见精神障碍的诊断和治疗。

【研究方向】抑郁障碍发病机制；应激、中枢与肠道菌群的交互影响；精神障碍的流行病学特征。主持和参与国家级及省部级科研课题10余项；在Molecular Psychiatry、Epidemiology and Psychiatric Sciences等杂志发表论文30余篇，其中SCI收录20余篇，2篇（Epidemiol Psychiatr Sci. 2021;30:e36；BMC Public Health. 2024;24(1):1639）入选ESI高被引；参编教材3部。

【近三年已发表论文】

(1) Liang W, Hou L, Wang W, et al. Alterations in miR-151a-3p of plasma-derived exosomes and associated multimodal neuroimaging patterns in major depressive disorder. Mol Psychiatry. 2025;30(11):5177-5191. doi:10.1038/s41380-025-03102-0(中科院一区，共同通讯作者 IF 12.2)

(2)Huang SM, Cai BY, Liu L, et al. Structural characterization of the urea transporter bound to the orally bioavailable inhibitor E3. Acta Pharmacol Sin. 2025;46(11):2989-2997. doi:10.1038/s41401-025-01595-7(中科院一区，共同第一作者 IF 10.8)

(3) Zhang Y, Wang W, Zhang X, et al. Neurotrophin-3 as a mediator in the link between PM2.5 exposure and psychiatric disorders: A Mendelian randomization study. Ecotoxicol Environ Saf. 2025;289:117658. doi:10.1016/j.ecoenv.2024. 117658 (中科院二区，TOP刊， 共同通讯作者 IF 6.8)

(4) Wang W, Wang Y, Shao K, et al. Global, regional, and national burden of bullying related mental disorders of adolescent from 1990 to 2019: A systematic analysis for the Global Burden of Disease Study 2019. Psychiatry Res. 2024;341:116154. doi:10.1016/j.psychres.2024.116154(中科院二区，最后位通讯作者 IF 5.3)

(5) Wang W, Wang Y, Wang F, et al. Notable dysthymia: evolving trends of major depressive disorders and dysthymia in China from 1990 to 2019, and projections until 2030. BMC Public Health. 2024;24(1):1585. Published 2024 Jun 13. doi:10.1186/s12889-024-18943-7 (中科院二区，TOP刊， 最后位通讯作者 IF 3.9)

(6) Zhang X, Yang L, Wang W, Yang L. Psychological distress, emotion regulation, neuroticism, and sexual relationship on patients with temporary ejaculation failure in vitro fertilization-embryo transfer treatment. Front Psychol. 2023;13:1090244. Published 2023 Jan 6. doi:10.3389/fpsyg.2022.1090244 (Q1 区，最后位通讯作者 IF 4.3)

(7) Chen, Wanyu, Yang, Lejin, et al. Adolescent-Parent Career Congruence and Career Adaptability in High School Students: Learning Factors' Mediation. J Career Dev. 2025;08948453251323825.(参与作者)

(8) Zhang X, Liu G, Zhong YN, et al. Structural basis of ligand recognition and activation of the histamine receptor family. Nat Commun.2024;15(1):8296. Published 2024 Sep 27. doi:10.1038/s41467-024-52585-y(参与作者)

(9) Zhang T, Sun L, Yin X, Chen H, Yang L, Yang X. Burden of drug use disorders in the United States from 1990 to 2021 and its projection until 2035: results from the GBD study. BMC Public Health. 2024;24(1):1639. Published 2024 Jun 19. doi:10.1186/s12889-024-19142-0 (参与作者)

(10) Yang X, Yang L, Zhang T, Zhang H, Chen H, Zuo X. Causal atlas between inflammatory bowel disease and mental disorders: a bi-directional 2-sample Mendelian randomization study. Front Immunol. 2023;14:1267834. Published 2023 Oct 13. doi:10.3389/fimmu.2023.1267834(参与作者)

(11) Shang P, Rong N, Jiang JJ, et al. Structural and signaling mechanisms of TAAR1 enabled preferential agonist design. Cell. 2023;186(24):5347-5362.e24. doi:10.1016/j.cell.2023.10.014(参与作者)