学习及工作经历
2014.05-至今 山东大学化学与化工学院 教授
2007.07-2014.04 山东大学化学与化工学院 副教授
2003.07-2007.07 山东大学化学与化工学院 讲师
2000.09-2003.07 北京大学化学与分子工程学院 理学博士
1997.09-2000.07 青岛科技大学应用化学专业 工学硕士
1993.09-1997.07 青岛科技大学应用化学专业 工学学士
主讲课程
《化工课程开发概要》《化工基础实验》《高等精细有机合成》
研究领域
1. 多功能纳米多孔材料的设计与制备。
研究重点是通过分子设计，构筑具有大比表面积、丰富表面基团和高吸附容量的多孔有机聚合物材料，探索其在废水处理，环境保护等方面的应用。
2. 基于卟啉的纳米复合材料在生物医学领域的应用。
主要致力于设计新型的卟啉基多孔有机聚合物材料，利用卟啉衍生物优异的仿生催化性能，并通过分子设计引入荧光，磁性等性能，设计合成新型的卟啉基纳米复合材料。在此基础上，创建用于检测生物分子和重要生命化学反应的新型高灵敏度与高选择性生物传感体系，同时探索用于疾病早期诊断和治疗的新技术。
招生信息
课题组每年拟招收学术硕士1名、专业硕士1名以及博士研究生1名，欢迎感兴趣的同学报考！
科研项目
1. 国家自然科学基金面上项目：金属卟啉多孔有机聚合物-无机纳米复合仿生酶的构建及其抗菌性能研究（2020.01-2023.12） 主持
2. 国家自然科学基金面上项目：基于卟啉骨架分子的共价有机框架的设计、制备及功能化研究（2015.01-2018.12） 主持
3. 山东省重点研发计划（重大科技创新工程竞争择优类）：船舶污水高效处理智能化关键技术及装备研制（2019.09-2021.12） 主持
4. 山东省重点研发计划（公益类科技攻关）：紫外/可见光辅助多相Fenton氧化工艺降解船舶生活污水研发（2019.09-2021.12） 主持
主要论著
【2022年】
1. Xiaojun Guo, Fei Yang,*, Lu Jing, Jie Li, Yanhong Li, Rui Ding, Binqiu Duan, Xiaomei Zhang,* “In-situ generation of highly active and four-in-one CoFe2O4/H2PPOP nanozyme: Mechanism and its application for fast colorimetric detection of Cr (VI)”, Journal of Hazardous Materials 2022, 431, 128621.
2. Rui Ding, Yanli Chen, Yanhong Li, Yancheng Zhu, Cheng Song, Xiaomei Zhang,* “Highly Efficient and Selective Gold Recovery Based on HypercrossLinking and Polyamine-Functionalized Porous Organic Polymers”, ACS Appl. Mater. Interfaces 2022, 14, 11803−11812.
3. Yanli Chen, Zhiwen Li, Rui Ding, Tingting Liu, Huijuan Zhao, Xiaomei Zhang,* “Construction of porphyrin and viologen-linked cationic porous organic polymer for efficient and selective gold recovery”, Journal of Hazardous Materials, 2022, 426, 128073.
【2021年】
1. Tingting Liu, Zhiwen Li, Mohan Chen, Huijuan Zhao, Zekun Zheng, Lin Cui,** Xiaomei Zhang,* “Sensitive electrochemical biosensor for Uracil-DNA glycosylase detection based on self-linkable hollow Mn/Ni layered doubled hydroxides as oxidase-like nanozyme for cascade signal amplification”, Biosensors and Bioelectronics, 2021, 194, 113607.
2. Huijuan Zhao, Tingting Liu, Lin Cui,* Yanhong Li, Fei Yang,* Xiaomei Zhang,* “Label-free and dual-amplified electrochemical bioanalysis of MUC1 based on an inorganic-organic polymer hybrid mimic peroxidase (AuNPs@Cu7S4@Cu/Mn-AzoPPOP) and catalytic hairpin assembly”, Sensors & Actuators: B. Chemical, 2021, 345, 130332.
3. Xiaojun Guo, Mohan Chen, Lu Jing, Jie Li, Yanhong Li, Rui Ding, Xiaomei Zhang,* “Porous polymers from octa(amino-phenyl)silsesquioxane and metalloporphyrin as peroxidase-mimicking enzyme for malathion colorimetric sensor”, Colloids and Surfaces B: Biointerfaces, 2021, 207, 112010.
4. Yanli Chen, Yishan Fang, Jingkun Yu, Wenqiang Gao, Huijuan Zhao, Xiaomei Zhang,* “A silsesquioxane-porphyrin-based porous organic polymer as a highly efficient and recyclable absorbent for wastewater treatment”, Journal of Hazardous Materials 2021, 406, 124769.
【2020年】
1. Dekang Li, Yishan Fang, Xiaomei Zhang* “Bacterial Detection and Elimination Using a Dual-Functional Porphyrin-Based Porous Organic Polymer with Peroxidase-Like and High Near-Infrared-Light-Enhanced Antibacterial Activity”, ACS Appl. Mater. Interfaces 2020, 12, 8989−8999.
2. Tingting Liu, Lin Cui,* Dekang Li, Wenqiang Gao, Lili Wu, Xiaomei Zhang,* “An enzyme-free and substrate-free electrochemical biosensor with robust porphyrin-based covalent-linked nanomaterial as nanoelectrocatalyst and efficient support for sensitive detection of uracil-DNA glycosylase”, Biosensors and Bioelectronics, 2020, 154, 112014.
3. Tingting Liu, Lin Cui,* Huijuan Zhao, Xiaomei Zhang,* “In situ generation of regularly ordered 2D ultrathin covalent organic framework films for highly sensitive photoelectrochemical bioanalysis”, ACS Appl. Mater. Interfaces 2020, 12, 47090−47098.
4. Yanhong Li, Yishan Fang, Wenqiang Gao, Xiaojun Guo, Xiaomei Zhang* “Porphyrin-Based Porous Organic Polymer as Peroxidase Mimics for Sulfide-Ion Colorimetric Sensing”, ACS Sustainable Chem. Eng. 2020, 8, 10870−10880.
5. Chao Cui, Quanbo Wang,* Cehua Xin, Qingyun Liu, Xiao Deng, Tingting Liu, Xiaohong Xu, Xiaomei Zhang,* “Covalent organic framework with bidentate ligand sites as reliable fluorescent sensor for Cu2+”, Microporous and Mesoporous Materials, 2020, 299, 110122.
6. Wenqiang Gao, Jing Tian, Yishan Fang, Tingting Liu, Xiumei Zhang, Xiaohong Xu, Xiaomei Zhang* “Visible-light-driven photo-Fenton degradation of organic pollutants by a novel porphyrin-based porous organic polymer at neutral pH”, Chemosphere, 2020, 243, 125334.
【2019年】
1. Tingting Liu, Jing Tian, Lin Cui, Qingyun Liu, Lili Wu, Xiaomei Zhang* “Facile strategy to prepare a metalloporphyrin-based hydrophilic porous organic polymer with enhanced peroxidase-like activity and high stability for colorimetric detection of H2O2 and glucose”, Colloids and Surfaces B: Biointerfaces, 2019, 178, 137–145.
【2018年】
1. Chao Cui, Quanbo Wang, Qingyun Liu, Xiao Deng, Tingting Liu, Dekang Li, Xiaomei Zhang,* “Porphyrin-based porous organic framework: An efficient and stable peroxidase-mimicking nanozyme for detection of H2O2 and evaluation of antioxidant”, Sensors & Actuators: B. Chemical, 2018, 277, 86–94.
2. Tingting Liu, Lu Jing, Lin Cui, Qingyun Liu, Xiaomei Zhang,* “Facile one-pot synthesis of a porphyrin-based hydrophilic porous organic polymer and application as recyclable absorbent for selective separation of methylene blue”, Chemosphere, 2018, 212, 1038-1046.
【2017年】
1. Xiao Deng, Yishan Fang, Sha Lin, Qian Cheng, Qingyun Liu,* Xiaomei Zhang* "Porphyrin-Based Porous Organic Frameworks as a Biomimetic Catalyst for Highly Efficient Colorimetric Immunoassay" ACS Appl. Mater. Interfaces 2017, 9, 3514-3523.
2. Tingting Liu, Xinyuan Hu, Yanfeng Wang,* Liyang Meng, Yanan Zhou, Jixiang Zhang, Min Chen,* Xiaomei Zhang,* “Triazine-based covalent organic frameworks for photodynamic inactivation of bacteria as type-II photosensitizers”, J. Photochemistry & Photobiology, B: Biology, 2017, 175, 156-162.
授权专利
1. 一种共价有机材料薄膜及其制备方法与应用
2. 一种卟啉聚合物的制备方法及应用
3. 检测尿嘧啶-DNA糖基化酶的、基于非酶纳米材料信号放大的无底物电化学生物传感器
4. 一种具有细菌检测与清除双功能的卟啉基多孔聚合物
