Paper Publications
Title of Award : 2,4,5-Trisubstituted Pyrimidines as Potent HIV-1 NNRTIs: Rational Design, Synthesis, Activity Evaluation, and Crystallographic Studies
Hits :
Institution:药学院
Title of Paper:2,4,5-Trisubstituted Pyrimidines as Potent HIV-1 NNRTIs: Rational Design, Synthesis, Activity Evaluation, and Crystallographic Studies
Journal:《Journal of Medicinal Chemistry》
First Author:康东伟
Document Code:B6CD2C31617A48FAABE36D596B435BCD
Volume:64
Issue:7
Page Number:4239
Translation or Not:No
Date of Publication:2021-04
Release Time:2021-05-29
Prev One:Exploring the hydrophobic channel of NNIBP leads to the discovery of novel piperidine-substituted thiophene[3,2-d]pyrimidine derivatives as potent HIV-1 NNRTIs
Next One:Design, synthesis, and evaluation of "dual-site"-binding diarylpyrimidines targeting both NNIBP and the NNRTI adjacent site of the HIV-1 reverse transcriptase