Title : In situ click chemistry-based rapid discovery of novel HIV-1 NNRTIs by exploiting the hydrophobic channel and tolerant regions of NNIBP
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Affiliation of Author(s):药学院
Title of Paper:In situ click chemistry-based rapid discovery of novel HIV-1 NNRTIs by exploiting the hydrophobic channel and tolerant regions of NNIBP
Journal:EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
First Author:康东伟
Document Code:3423B1A68F9E4D4E991CC3BC4577D04C
Volume:193
Translation or Not:no
Date of Publication:2020-05-01
Pre One : Structure-Based Bioisosterism Yields HIV-1 NNRTIs with Improved Drug-Resistance Profiles and Favorable Pharmacokinetic Properties
Next One : Exploring the hydrophobic channel of NNIBP leads to the discovery of novel piperidine-substituted thiophene[3,2-d]pyrimidine derivatives as potent HIV-1 NNRTIs
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