Title : Identification of novel potent HIV-1 inhibitors by exploiting the tolerant regions of the NNRTIs binding pocket
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Affiliation of Author(s):药学院
Title of Paper:Identification of novel potent HIV-1 inhibitors by exploiting the tolerant regions of the NNRTIs binding pocket
Journal:EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
First Author:孙彦莹
Document Code:A9B63B9A92324DFEB3F82320DC1DF5D1
Volume:214
Translation or Not:no
Date of Publication:2021-03-15
Pre One : Exploiting the tolerant region I of the non-nucleoside reverse transcriptase inhibitor (NNRTI) binding pocket. Part 2: Discovery of diarylpyrimidine derivatives as potent HIV-1 NNRTIs with high Fsp(3) values and favorable drug-like properties
Next One : Novel indolylarylsulfone derivatives as covalent HIV-1 reverse transcriptase inhibitors specifically targeting the drug-resistant mutant Y181C
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