• 2014-9 — 2015-9
  美国约翰霍普金斯大学
  外科学
  博士
• 2010-9 — 2016-7
  吉林大学
  外科学
  博士

• 2021-07 — 至今
   乳腺外科  山东大学第二医院 
  临床副教授
• 2022-09 — 至今
   乳腺外科  山东大学第二医院 
  副主任医师
• 2018-08 — 2022-08
   乳腺外科  山东大学第二医院 
  主治医师
• 2016-07 — 2018-07
   乳腺外科  山东大学第二医院 
  医师

• 山东预防医学会乳腺疾病防控分会常务委员兼秘书
• 山东省抗癌协会乳腺肿瘤分会委员兼秘书
• 山东省医学会外科学分会委员
• 山东省医学会科学普及分会委员
• 山东省健康管理协会乳腺疾病预防与控制专业委员会常务委员
• 山东药理学会化疗药理专业委员会常务委员
• 山东省卫生保健协会乳腺甲状腺专业委员会委员
• 山东省疼痛医学会乳腺癌专业委员会委员
• 山东中医药学会乳腺病专业委员会委员
• 山东省医学会乳腺疾病多学科联合委员会工作组委员
• 山东省医学会外科学分会实验外科学组委员
• 中国健康管理协会乳腺健康管理分会理事
• 中国医师协会健康传播工作委员会成员
• Advanced Science，Cancer Science，Talanta，Journal of Raman Spectroscopy, Analytical Methods等杂志审稿人

基于光谱学的乳腺癌早期诊断与发病机制研究

(1) Neoadjuvant pyrotinib and trastuzumab in HER2-positive breast cancer with no early response (NeoPaTHer): efficacy, safety and biomarker analysis of a prospective, multicentre, response-adapted study.Signal Transduction and Targeted Therapy.2025,10 (1):45

(2) 贾亦宁.Raman spectroscopy and exosomes-based machine learning predicts the efficacy of neoadjuvant therapy for HER2-positive breast cancer.Analytical Chemistry.2025,97 (2):1374-1385

(3) Recent progress in Surface-Enhanced Raman Spectroscopy detection of biomarkers in liquid biopsy for breast cancer.Frontiers in Oncology.2024,14 :1400498

(4) Label-free Raman spectroscopy reveals tumor microenvironmental changes induced by intermittent fasting for the prevention of breast cancer in animal model.Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy.2024 (317):124387

(5) Genomic and transcriptomic analysis of breast cancer identifies novel signatures associated with response to neoadjuvant chemotherapy.Genome Medicine.2024,16 (1):11

(6) Integrated SERS-Vertical Flow Biosensor Enabling Multiplexed Quantitative Profiling of Serological Exosomal Proteins in Patients for Accurate Breast Cancer Subtyping.ACS Nano.2023,17 (4):4077-4088

(7) 刘丽媛.Using machine learning to identify gene interaction networks associated with breast cancer.BMC cancer.2022 (1)

(8) Artificial Intelligent Label-Free SERS Profiling of Serum Exosomes for Breast Cancer Diagnosis and Postoperative Assessment.Nano Letters.2022,22 (19):7910-7918

(9) Near-infrared II plasmonic porous cubic nanoshells for in vivo noninvasive SERS visualization of sub-millimeter microtumors.Nature Communications.2022,13 (1):5249

(10) Label-Free Plasmon-Enhanced Spectroscopic HER2 Detection for Dynamic Therapeutic Surveillance of Breast Cancer.Analytical Chemistry.2022,94 (37):12762-12771

(11) Structural symmetry effects in plasmonic metal-semiconductor hybrid heterostructures for multimodal cancer phototheranostics.Chemical Engineering Journal.2022,44 :136707

(12) Prognostic value of gamma-interferon-inducible lysosomal thiol reductase expression in female patients diagnosed with breast cancer.International Journal of Cancer.2022,150 (4):705-717

(13) Relationship of lifestyle habits to health-related quality of life of recently diagnosed Breast Cancer patients: a comparison between younger and older women in China.Frontiers in Public Health.2021,9 :767151

(14) Clinical practice guidelines for pre-operative evaluation of breast cancer: Chinese Society of Breast Surgery (CSBrS) practice guidelines 2021.Chinese Medical Journal.2021,134 (18):2147-2149

(15) Spectroscopy-Assisted Label-free Molecular Analysis of Live Cell Surface with Vertically Aligned Plasmonic Nanopillars.Small.2021 :e2100161

(16) 于理想.XRCC5/6 polymorphisms and their interactions with smoking, alcohol consumption, and sleep satisfaction in breast cancer risk: A Chinese multi-center study.CANCER MEDICINE.2021,10 (8):2752

(17) 周飞.Comparison of Conservative versus Surgical Treatment Protocols in Treating Idiopathic Granulomatous Mastitis: A Meta-Analysis.BREAST CARE.2020,15 (4):415

(18) Rizwan, Asif.Mapping the genetic basis of breast microcalcifications and their role in metastasis.scientific reports.2018,8

(19) Gao, Pin.The Clinical Application of Raman Spectroscopy for Breast Cancer Detection.JOURNAL OF SPECTROSCOPY.2017

(20) Paidi, Santosh Kumar.Label-Free Raman Spectroscopy Detects Stromal Adaptations in Premetastatic Lungs Primed by Breast Cancer.cancer research.2017,77 (2):247

1. 基于拉曼光谱的ACAT2介导的乳腺癌前病变浸润转化可视化诊疗研究, 2023/12/01

2. ACAT2介导的基于拉曼光谱的乳腺癌前病变浸润转化可视化及干预关键技术研究, 2023/12/01

3. （包干项目）基于SERS技术的乳腺癌前病变浸润转化可视化标志物的筛选验证及干预机制研究, 2022/11/01-2025/12/30

4. 基于拉曼光谱的乳腺导管内癌浸润转化可视化及机制研究, 2021/06/01

5. Cyclin D1 介导的基于拉曼光谱的乳腺癌前病变浸润转化可视化及其干预机制研究, 2021/06/01

6. 乳腺癌前病变多模态可视化及机制研究, 2020/12/11-2023/12/31

7. 热休克蛋白90α在乳腺癌新辅助化疗早期疗效评价中的临床应用研究, 2020/12/01

8. uMtCK调控TGF-β/Smads通路促进胃癌发生发展的作用及分子机制研究, 2019/04/26-2022/06/30

9. 基于拉曼光谱的乳腺癌细胞微钙化形成机制研究, 2017/08/17-2020/12/31

1. 外科学

1.贾亦宁

2.李永琪

1.第二临床学院   普通外科   2025  

1. 中华医学会乳腺外科临床实践指南2021版