教师简介


韩冰,男,理学博士,中共党员,山东大学病原生物学系副主任,教授、博士研究生导师,美国阿尔伯特.爱因斯坦医学院客座助理教授,山东大学齐鲁青年学者、北京市青年人才托举工程青托人才。韩冰博士20176月获得西南大学博士学位,2014年9月年至20199月分别以公派联合培养博士研究生以及博士后的身份在Albert Einstein College of Medicine病理学系进行学习和工作,并于2020年入职山东大学基础医学院。韩冰教授长期从事微孢子虫及弓形虫致病机制相关研究,近年来以第一作者身份在Clinical Microbiology ReviewsIF=22.556)、pLoS PathogensIF=6.218)、mBioIF=6.784)等国际权威杂志发表多篇病原致病机制研究相关SCI论文,总影响因子大于55分,相关成果曾被重庆新闻联播以及新华社等国内主流媒体头版报道,在国内外病原生物学研究领域具有重要影响力。


研究概况

微孢子虫以及弓形虫致病机制。

论文成果

(1) Host cell manipulation by microsporidia secreted effectors: Insights into intracellular pathogenesis.JOURNAL OF EUKARYOTIC MICROBIOLOGY.2024

(2) 关靖宇.Microsporidian EnP1 alters host cell H2B monoubiquitination and prevents ferroptosis facilitating microsporidia survival.PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF T.2024,121 (34)

(3) Overcoming research challenges: In vitro cultivation of Ameson portunus (Phylum Microsporidia).JOURNAL OF INVERTEBRATE PATHOLOGY.2024,204

(4) Anti-Toxoplasma gondii effect of tylosin in vitro and in vivo.Parasite&Vectors.2024,17 (1)

(5) 韩冰.Microsporidiosis in Humans.CLINICAL MICROBIOLOGY REVIEWS.2021,34 (4)

(6) 王永亮.Upregulation of lncRNA147410.3 in the Brain of Mice With Chronic Toxoplasma Infection Promoted Microglia Apoptosis by Regulating Hoxb3.FRONTIERS IN CELLULAR NEUROSCIENCE.2021,15

(7) 韩冰.Invasion of Host Cells by Microsporidia.Frontiers in Microbiology.2020,11

(8) 周春雪.Quantitative Peptidomics of Mouse Brain After Infection With Cyst-Forming Toxoplasma gondii.Frontiers in Immunology.2021,12

(9) 周春雪.Quantitative Peptidomics of Mouse Brain After Infection With Cyst-Forming Toxoplasma gondii.Frontiers in Immunology.2021 (12)

(10) Bing Han.Encephalitozoon: Tissue Culture, Cryopreservation, and Murine Infection.Current protocols in microbiology.2018,52 (1)

(11) Bing Han.Microsporidia: Obligate intracellular pathogens within the fungal kingdom.Microbiology Spectrum.2017,5 (2)

(12) Bing Han.Therapeutic targets for the treatment of microsporidiosis in humans.Expert opinion on therapeutic targets.2018,22 (11)

(13) Bing Han.An Ultrastructural Study of the Extruded Polar Tube of Anncaliia algerae (Microsporidia).Journal of Eukaryotic Microbiology.2019 (67)

(14) Bing Han.The role of microsporidian polar tube protein 4 (PTP4) in host cell infection.Plos pathogens.2017,13 (4)

(15) Bing Han.Microsporidia Interact with Host Cell Mitochondria via Voltage-Dependent Anion Channels Using Sporoplasm Surface Protein 1.mBio.2019,10 (4)

(16) Bing Han.Invasion of Host Cells by Microsporidia.Frontiers in Microbiology.2020,11 (172)

(17) Bing Han.Microsporidiosis in humans.Clinical Microbiology Reviews.2021

(18) Cui, Lin-Lin.Urine proteomics for profiling of mouse toxoplasmosis using liquid chromatography tandem mass spectrometry analysis.Parasites & Vectors.2021,14 (1)

(19) Yongliang Wang.Upregulation of lncRNA147410.3 in the Brain of Mice With Chronic Toxoplasma Infection Promoted Microglia Apoptosis by Regulating Hoxb3..Frontiers in cellular neurosciense.2021 (648047)

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