Dr. Bing Han finished his Ph.D project in Dr. Louis Weiss laboratory of pathology department in Albert Einstein College of Medicine, New York, USA, as a joint student founded by Chinese Scholarship Council and obtained his Ph.D in Southwest University, Chongqing, China, in 2017. He remained in Dr. Louis Weiss laboratory as a postdoctoral research fellow, working on the microsporidia and host cell interaction during cell invasion. Dr. Han is currently Full Professor at the School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, China. His research interests include the molecular mechanism of microsporidia polar tube infecting host cells, the interaction of host mitochondria with microsporidia sporoplasm during cell development and the interaction of Toxoplasma gondii with host during infection. He has published more than 20 peer-reviewed papers in the Journal Clinical Microbiology Reviews、pLoS Pathogens、mBio、Frontiers in Microbiology、Expert opinion on therapeutic targets.

The pathogenesis of Microsporidia and Toxoplasma gondii.

(1) Host cell manipulation by microsporidia secreted effectors: Insights into intracellular pathogenesis .JOURNAL OF EUKARYOTIC MICROBIOLOGY .2024

(2)关靖宇. Microsporidian EnP1 alters host cell H2B monoubiquitination and prevents ferroptosis facilitating microsporidia survival .PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF T .2024 ,121 (34)

(3) Overcoming research challenges: In vitro cultivation of Ameson portunus (Phylum Microsporidia) .JOURNAL OF INVERTEBRATE PATHOLOGY .2024 ,204

(4) Anti-Toxoplasma gondii effect of tylosin in vitro and in vivo .Parasite&Vectors .2024 ,17 (1)

(5)韩冰. Microsporidiosis in Humans .CLINICAL MICROBIOLOGY REVIEWS .2021 ,34 (4)

(6)王永亮. Upregulation of lncRNA147410.3 in the Brain of Mice With Chronic Toxoplasma Infection Promoted Microglia Apoptosis by Regulating Hoxb3 .FRONTIERS IN CELLULAR NEUROSCIENCE .2021 ,15

(7)韩冰. Invasion of Host Cells by Microsporidia .Frontiers in Microbiology .2020 ,11

(8)周春雪. Quantitative Peptidomics of Mouse Brain After Infection With Cyst-Forming Toxoplasma gondii .Frontiers in Immunology .2021 ,12

(9)周春雪. Quantitative Peptidomics of Mouse Brain After Infection With Cyst-Forming Toxoplasma gondii .Frontiers in Immunology .2021 (12)

(10)Bing Han. Encephalitozoon: Tissue Culture, Cryopreservation, and Murine Infection .Current protocols in microbiology .2018 ,52 (1)

(11)Bing Han. Microsporidia: Obligate intracellular pathogens within the fungal kingdom .Microbiology Spectrum .2017 ,5 (2)

(12)Bing Han. Therapeutic targets for the treatment of microsporidiosis in humans .Expert opinion on therapeutic targets .2018 ,22 (11)

(13)Bing Han. An Ultrastructural Study of the Extruded Polar Tube of Anncaliia algerae (Microsporidia) .Journal of Eukaryotic Microbiology .2019 (67)

(14)Bing Han. The role of microsporidian polar tube protein 4 (PTP4) in host cell infection .Plos pathogens .2017 ,13 (4)

(15)Bing Han. Microsporidia Interact with Host Cell Mitochondria via Voltage-Dependent Anion Channels Using Sporoplasm Surface Protein 1 .mBio .2019 ,10 (4)

(16)Bing Han. Invasion of Host Cells by Microsporidia .Frontiers in Microbiology .2020 ,11 (172)

(17)Bing Han. Microsporidiosis in humans .Clinical Microbiology Reviews .2021

(18)Cui, Lin-Lin. Urine proteomics for profiling of mouse toxoplasmosis using liquid chromatography tandem mass spectrometry analysis .Parasites & Vectors .2021 ,14 (1)

(19)Yongliang Wang. Upregulation of lncRNA147410.3 in the Brain of Mice With Chronic Toxoplasma Infection Promoted Microglia Apoptosis by Regulating Hoxb3. .Frontiers in cellular neurosciense .2021 (648047)

1. 一种微孢子虫荧光染色标记方法及应用

2. 一种微孢子虫荧光染色标记方法及应用

1. （包干项目）lncRNA11496靶向Mef2c调节神经突触在弓形虫感染引起宿主精神行为异常中的作用及调控机制研究, 2021/12/23-2024/12/31

2. 脑炎微孢子虫与宿主线粒体VDAC蛋白的互作机制研究, 2020/09/18-2023/12/31