王一鹤，副研究员，硕士生导师，山东大学青年学者未来计划获得者。目前研究方向主要集中在以微流控技术为平台的交叉应用领域，如肿瘤类器官芯片、病原微生物检测、仿生高分子材料的开发与应用等研究。

发表论文三十余篇，其中以第一/通讯作者在Advanced Science、Journal of Nanobiotechnology、Advanced Healthcare Materials等国际权威期刊上发表SCI论文十余篇。作为主持人承担国家自然科学基金青年项目，山东省重点研发项目子课题等，作为骨干参与了国家自然科学基金面上项目、国家重点研发计划、青岛市关键技术攻关及产业化示范类项目等。

• 多伦多大学
  化学
  博士生
• 浙江大学
  化学
  硕士生
• 中国石油大学（华东）
  应用化学
  学士

•  机械与工业工程系  多伦多大学 
  博士后

1.肿瘤类器官芯片

2.病原微生物检测

3.仿生高分子材料

(1) 王帅.Concurrent Detection of Amyloid-β Biomarkers via Dual-Channel Graphene Field-Effect Transistor with Liquid-Metal Van Der Waals Contacts for Alzheimer Screening.ACS Sensors.2025,10 (7):5067–5076

(2) 李珺.Bipolar Ionic Diode with a Transformable Polyelectrolyte Network for High-Efficiency Ion Transport and Enhanced Sensitivity in Fluorescence-Based Heavy Metal Ion Detection.Analytical Chemistry.2025,97 (28):15018–15027

(3) 王一鹤.In situ and dynamic screening of extracellular vesicles as predictive biomarkers in immune-checkpoint inhibitor therapies.Journal of Nanobiotechnology.2025 (23):411

(4) 王一鹤,刘梦绮.A Microfluidic 3D-Tumor-Spheroid Model for the Evaluation of Targeted Therapies from Angiogenesis-Related Cytokines at the Single Spheroid Level.Advanced Healthcare Materials.2024,13 (31):2402321

(5) 王一鹤.Recent methods of droplet microfluidics and their applications in spheroids and organoids.Lab on a Chip.2023 (23):1080

(6) Yihe Wang.Prediction of DNA Integrity from Morphological Parameters Using a Single‐Sperm DNA Fragmentation Index Assay.Advanced Science.2019,6 :1900712

(7) Yihe Wang.Two-dimensional arrays of cell-laden polymer hydrogel modules.Biomicrofluidics.2016,10 :014110

(8) Yihe Wang.Exploring a direct injection method for microfluidic generation of polymer microgels.Lab on a Chip.2013,13 (13):2547-2553

(9) Yihe Wang.Excess Molar Volumes of 1,3-Diethyl Propanedioate with Methanol, Ethanol, Propan-1-ol, Propan-2-ol, Butan-2-ol, 2-Methyl-propan-1-ol, and Pentan-1-ol at T = (288.15, 298.15, 313.15, and 328.15) K.J. Chem. Eng. Data.2010,55 (9):4029–4032

(10) Yihe Wang.Excess molar enthalpies of diethyl malonate+ (1-butanol, 2-methyl-1-propanol, 1-pentanol, n-heptane, and ethyl acetate) at T= (288.2, 298.2, 313.2, 328.2, 338.2, and 348.2 K) and p = 101.3 kPa.Fluid Phase Equilibria.2010,291 (1):8-12

(11) Yihe Wang.Excess Molar Enthalpies of Diethyl Malonate + (Methanol, + Ethanol, + 1-Propanol, and + 2-Propanol) at T = (288.2, 298.2, 313.2, and 328.2) K and p = 101.3 kPa.J. Chem. Eng. Data.2009,55 (1):381–384

(12) Mohammad Simchi.High-throughput sperm DNA analysis at the single-cell and population levels.Analyst.2023,148 :3748-3757

(13) 褚玉金.Rapid and High-Throughput SARS-CoV-2 RNA Detection without RNA Extraction and Amplification by Using a Microfluidic Biochip.chemistry-a European journal.2022,28 (18):e202104054

(14) 宋方腾.Multi-Phenotypic Exosome Secretion Profiling Microfluidic Platform for Exploring Single-Cell Heterogeneity.Small Methods.2022 ( 2200717)

(15) 王超.High-Throughput, Living Single-Cell, Multiple Secreted Biomarker Profiling Using Microfluidic Chip and Machine Learning for Tumor Cell Classification.Advanced Healthcare Materials.2022,11 (13)

(16) Jiaoyan Qiu.Lys-AuNPs@MoS2 Nanocomposite Self-Assembled Microfluidic Immunoassay Biochip for Ultrasensitive Detection of Multiplex Biomarkers for Cardiovascular Diseases.Analytical Chemistry.2022,94 (11):4720-4728

(17) Elisabeth Prince.Microfluidic arrays of breast tumor spheroids for drug screening and personalized cancer therapies.Advanced Healthcare Materials.2021,11 (1):2101085

(18) Jae Bem You.Machine learning for sperm selection.Nat Rev Urol.2021,18 (7):387-403

(19) Mohammad Simchi.Selection of high-quality sperm with thousands of parallel channels.Lab on a Chip.2021,21 (12):2464-2475

(20) Jason Riordon.Two-Dimensional Planar Swimming Selects for High DNA Integrity Sperm.Lab on a Chip.2019,19 (13):2161-2167

(21) Christopher McCallum.Deep learning-based selection of human sperm with high DNA integrity.Commun Biol..2019,3 (2):250

1. 一种仿生超疏水-亲水集成孔板及基于该孔板的高通量自动化核酸建库仪

1. 基于微流控仿生三维多细胞肿瘤芯片和机器学习的肿瘤耐药机制研究, 2020/09/18-2023/12/31

2. 肿瘤和脑血管疾病标记物高通量低成本检测芯片与系统的研发-1, 2021/05/01-2024/06/30

3. 用于单细胞外泌体实时分析的传感芯片研究, 2021/10/12-2025/12/31

4. 小型自动化病原微生物建库仪开发及产业化, 2022/05/11-2025/05/10

5. 山东大学青年学者未来计划

1. 专业英语（理工）

2. 印象北美——留学生活见闻

3. 电子信息工程前沿案例分析

4. 毕业论文（设计）

5. 形势与政策

1.杨洪菲

2.孙悦

3.杨宁恺

4.刘梦绮

1.海洋研究院   光电信息工程、海洋应用与科学技术   2025  

2.海洋研究院   电子科学与技术   2024  

3.海洋研究院   电子科学与技术   2023