目前研究方向主要集中在以微流控技术为平台的交叉应用领域,如肿瘤类器官芯片、病原微生物检测、单细胞空间组学、仿生高分子材料的开发与应用等研究。
1.肿瘤类器官芯片
2.病原微生物检测
3.单细胞空间组学
(1) 刘梦绮,王一鹤.A Microfluidic 3D-Tumor-Spheroid Model for the Evaluation of Targeted Therapies from Angiogenesis-Related Cytokines at the Single Spheroid Level.Advanced Healthcare Materials.2024 (2402321)
(2) 王一鹤.Recent methods of droplet microfluidics and their applications in spheroids and organoids.Lab on a Chip.2023 (23):1080
(3) Yihe Wang.Prediction of DNA Integrity from Morphological Parameters Using a Single‐Sperm DNA Fragmentation Index Assay.Advanced Science.2019,6 :1900712
(4) Yihe Wang.Two-dimensional arrays of cell-laden polymer hydrogel modules.Biomicrofluidics.2016,10 :014110
(5) Yihe Wang.Exploring a direct injection method for microfluidic generation of polymer microgels.Lab on a Chip.2013,13 (13):2547-2553
(6) Yihe Wang.Excess Molar Volumes of 1,3-Diethyl Propanedioate with Methanol, Ethanol, Propan-1-ol, Propan-2-ol, Butan-2-ol, 2-Methyl-propan-1-ol, and Pentan-1-ol at T = (288.15, 298.15, 313.15, and 328.15) K.J. Chem. Eng. Data.2010,55 (9):4029–4032
(7) Yihe Wang.Excess molar enthalpies of diethyl malonate+ (1-butanol, 2-methyl-1-propanol, 1-pentanol, n-heptane, and ethyl acetate) at T= (288.2, 298.2, 313.2, 328.2, 338.2, and 348.2 K) and p = 101.3 kPa.Fluid Phase Equilibria.2010,291 (1):8-12
(8) Yihe Wang.Excess Molar Enthalpies of Diethyl Malonate + (Methanol, + Ethanol, + 1-Propanol, and + 2-Propanol) at T = (288.2, 298.2, 313.2, and 328.2) K and p = 101.3 kPa.J. Chem. Eng. Data.2009,55 (1):381–384
(9) Mohammad Simchi.High-throughput sperm DNA analysis at the single-cell and population levels.Analyst.2023,148 :3748-3757
(10) 褚玉金.Rapid and High-Throughput SARS-CoV-2 RNA Detection without RNA Extraction and Amplification by Using a Microfluidic Biochip.chemistry-a European journal.2022,28 (18):e202104054
(11) 宋方腾.Multi-Phenotypic Exosome Secretion Profiling Microfluidic Platform for Exploring Single-Cell Heterogeneity.Small Methods.2022 ( 2200717)
(12) 王超.High-Throughput, Living Single-Cell, Multiple Secreted Biomarker Profiling Using Microfluidic Chip and Machine Learning for Tumor Cell Classification.Advanced Healthcare Materials.2022,11 (13)
(13) Jiaoyan Qiu.Lys-AuNPs@MoS2 Nanocomposite Self-Assembled Microfluidic Immunoassay Biochip for Ultrasensitive Detection of Multiplex Biomarkers for Cardiovascular Diseases.Analytical Chemistry.2022,94 (11):4720-4728
(14) Elisabeth Prince.Microfluidic arrays of breast tumor spheroids for drug screening and personalized cancer therapies.Advanced Healthcare Materials.2021,11 (1):2101085
(15) Jae Bem You.Machine learning for sperm selection.Nat Rev Urol.2021,18 (7):387-403
(16) Mohammad Simchi.Selection of high-quality sperm with thousands of parallel channels.Lab on a Chip.2021,21 (12):2464-2475
(17) Jason Riordon.Two-Dimensional Planar Swimming Selects for High DNA Integrity Sperm.Lab on a Chip.2019,19 (13):2161-2167
(18) Christopher McCallum.Deep learning-based selection of human sperm with high DNA integrity.Commun Biol..2019,3 (2):250
1. 基于微流控仿生三维多细胞肿瘤芯片和机器学习的肿瘤耐药机制研究, 2020/09/18-2023/12/31
2. 肿瘤和脑血管疾病标记物高通量低成本检测芯片与系统的研发-1, 2021/05/01-2024/06/30
3. 用于单细胞外泌体实时分析的传感芯片研究, 2021/10/12-2025/12/31
4. 小型自动化病原微生物建库仪开发及产业化, 2022/05/11-2025/05/10
5. 山东大学青年学者未来计划
1. 专业英语(理工)
2. 专业英语(理工)
3. 印象北美——留学生活见闻
4. 电子信息工程前沿案例分析
5. 毕业论文(设计)
6. 形势与政策
1.孙悦
2.杨宁恺
3.刘梦绮
1.海洋研究院 电子科学与技术 2024
2.海洋研究院 电子科学与技术 2023