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More >>Professor Supervisor of Doctorate Candidates Supervisor of Master's Candidates
Gender:Male
Biography
袁中尚,男,生物统计学教授、博士生导师,概率论与数理统计专业博士毕业,国家青年拔尖人才、山东省杰出青年基金获得者、山东省泰山学者青年专家、山东大学杰出中青年学者,中国卫生信息与健康医疗大数据学会统计理论与方法专委会副主委,中国卫生信息与健康医疗大数据学会卫生统计教育专委会常委,中国数学会医学数学专委会委员。2009年5月-2009年6月,参加新加坡国立大学(NUS)基因组暑期班,2009年10月-2010年10月,作为国家公派联合培养博士生访问美国北卡大学教堂山分校(UNC-CH)生物统计系,2011年7月-2013年7月在山东大学公共卫生学院生物统计学系完成了师资博士后研究,2014年7月-2020年7月,在山东省内分泌代谢研究所从事博士后研究,2017年10月-2019年12月,美国密歇根大学生物统计学系访问学者。主要研究方向为跨组学数据整合与系统流行病学统计理论方法,先后主持国家自然科学基金面上项目4项、山东省自然科学基金重大基础研究1项、国家自然科学基金青年项目、国家重点研发计划子课题、国家科技支撑计划子课题、中国博士后科学基金面上项目、山东省博士后创新专项等,以第一作者或通讯作者在国内外发表SCI论文31篇,参编专著2部。
主要代表性成果:
1. Lu Liu, Ran Yan, Ping Guo, Jiadong Ji, Weiming Gong, Fuzhong Xue, Zhongshang Yuan*, Xiang Zhou*, Conditional transcriptome-wide association study for fine-mapping candidate causal genes, Nature Genetics, 2024, 56: 348–356
2. Zhongshang Yuan, Huanhuan Zhu, Ping Zeng, Sheng Yang, Shiquan Sun, Can Yang, Jin Liu, Xiang Zhou*, Testing and controlling for horizontal pleiotropy with probabilistic Mendelian randomization in transcriptome-wide association studies, Nature Communications, 2020, 11(1): 3861
3. Zhongshang Yuan, Lu Liu, Ping Guo, Ran Yan, Fuzhong Xue, Xiang Zhou*, Likelihood-based Mendelian randomization analysis with automated instrument selection and horizontal pleiotropic modeling, Science Advances, 2022, 8(9)
4. Lu Liu, Ping Zeng, Fuzhong Xue, Zhongshang Yuan*, Xiang Zhou*, Multi-trait transcriptome-wide association studies with probabilistic Mendelian randomization, The American Journal of Human Genetics, 2021, 108(2): 240-256
5. Jiadong Ji, Zhendong Hou, Yong He, Lei Liu, Fuzhong Xue, Hao Chen*, Zhongshang Yuan*, Differential network knockoff filter with application to brain connectivity analysis, Statistic in Medicine, 2024, 43(20):3830-3861
6. Weiming Gong+, Ping Guo+, Yuanming Li, Lu Liu, Ran Yan, Shuai Liu, Shukang Wang, Fuzhong Xue, Xiang Zhou, Zhongshang Yuan*, Role of the Gut-Brain Axis in the Shared Genetic Etiology Between Gastrointestinal Tract Diseases and Psychiatric Disorders: A Genome-Wide Pleiotropic Analysis, JAMA Psychiatry, 2023, 80(4):360-370
7. Ping Guo+, Weiming Gong+, Yuanming Li, Lu Liu, Ran Yan, Yanjun Wang, Yanan Zhang, Zhongshang Yuan*, Pinpointing novel risk loci for Lewy body dementia and the shared genetic etiology with Alzheimer’s disease and Parkinson’s disease: a large-scale multi-trait association analysis, BMC Medicine, 2022, 20:214
8. Yanan Zhang, Meng Zhao, Ping Guo, Yanjun Wang, Lu Liu, Jinghua Zhao, Ling Gao, Zhongshang Yuan*, Fuzhong Xue*, Jiajun Zhao*, Mendelian randomisation highlights hypothyroidism as a causal determinant of idiopathic pulmonary fibrosis, EBioMedicine, 2021, 73: 2352-3964