方浩

-
教授
博士生导师
硕士生导师
- 主要任职:山东大学药学院药物化学研究所教授、博士生导师
- 性别:男
- 毕业院校:中国药科大学
- 学历:博士研究生毕业
- 学位:博士生
- 在职信息:在职
- 所在单位:药学院
- 入职时间: 2004-12-23
- 所属院系:
齐鲁医学院
- 学科:药物化学
- 电子邮箱:9466efb0b56ed53efa51cab15719235b9e368529417a48e0fe4e7cfb1a190e4fbf10138590fba56312a2be57014de7e16b507a013cbc9f583d7a4fea81564e229ffda4fd1cbc9bfa3fd69b79fe9ac554f72909e549431f67b3431a97ac5e92d822cd2a43654316c101de7ae6dc75e386c8c3844550c5b5788903167350fe1717
访问量:
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[1]
王海钠.
五育融合视域下药学专业实验教学体系建设实践.
《药学教育》,
41,
27,
2025.
-
[2]
Chang, Yingjie.
Simultaneous inhibition of FLT3 and HDAC by novel 6-ethylpyrazine-2-Carboxamide derivatives provides therapeutic advantages in acute myelocytic leukemia.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY,
279,
2024.
-
[3]
.
Development of a First-in-Class DNMT1/HDAC Inhibitor with Improved Therapeutic Potential and Potentiated Antitumor Immunity.
Journal of Medicianal Chemistry,
67,
16480,
2024.
-
[4]
.
Design and synthesis of novel benzoic acid derivatives as striatal-enriched protein tyrosine phosphatase (STEP) inhibitors with neuroprotective properties.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY,
2024.
-
[5]
Liang, Tao.
Design, synthesis and biological evaluation of 3, 4-disubstituted-imidazolidine-2, 5-dione derivatives as HDAC6 selective inhibitors..
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY,
221,
113526,
2021.
-
[6]
Liang, Tao.
Targeting histone deacetylases for cancer therapy: Trends and challenges.
ACTA PHARMACEUTICA SINICA B,
2023.
-
[7]
Zhao, Yunpeng.
Design, synthesis and bioactivity evaluations of 8-substituted-quinoli- ne-2-carboxamide derivatives as novel histone deacetylase (HDAC) inhibitors.
Bioorganic & medicinal chemistry,
85,
2023.
-
[8]
.
Deciphering the Allosteric Activation Mechanism of SIRT6 Using Molecular Dynamics Simulations.
Journal of Chemical Information and Modeling,
63,
5896,
2023.
-
[9]
Liang, Tao.
Potential applications of BPFP1 in Bcl-2 protein quantification, carcinoma cell visualization, cell sorting and early cancer diagnosis.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY,
224,
113725,
2021.
-
[10]
.
Discovery of benzofuran-2-carboxylic acid derivatives as lymphoid tyrosine phosphatase (LYP) inhibitors for cancer immunotherapy.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY,
258,
2023.
-
[11]
Liu, Meng.
Strategies to overcome drug resistance using SHP2 inhibitors..
ACTA PHARMACEUTICA SINICA B,
11,
3908-3924,
2021.
-
[12]
.
Fast Identification of Novel Lymphoid Tyrosine Phosphatase Inhibitors Using Target-Ligand Interaction-Based Virtual Screening.
Journal of Medicianal Chemistry,
57,
9309-9322,
2014.
-
[13]
Wen Li.
Recent advances in small molecule PROTACs for the treatment of cancer..
Curr Med Chem,
28,
4893-4909,
2020.
-
[14]
Liu, Meng.
Discovery of a Novel Benzimidazole Derivative Targeting Histone Deacetylase to Induce Ferroptosis and Trigger Immunogenic Cell Death.
Journal of Medicianal Chemistry,
2024.
-
[15]
邱雪婷.
An in-line method for high-throughput screening of protein tyrosine phosphatase receptor type O inhibitors by capillary electrophoresis based on electrophoretically mediated microanalysis.
Journal of chromatography A,
1713,
2024.
-
[16]
.
Discovery of benzofuran-2-carboxylic acid derivatives as lymphoid tyrosine phosphatase (LYP) inhibitors for cancer immunotherapy.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY,
2023.
-
[17]
聂义明.
Development of QSRR model for hydroxamic acids using PCA-GA-BP algorithm incorporated with molecular interaction-based features.
FRONTIERS IN CHEMISTRY,
2022.
-
[18]
Liang, Xiao.
Design, synthesis and biological evaluation of hydantoin derivatives as Mcl-1 selective inhibitors.
Bioorganic Chemistry,
121,
105643,
2022.
-
[19]
侯旭奔.
Discovery of Novel Src Homology-2 Domain-Containing Phosphatase 2 and Histone Deacetylase Dual Inhibitors with Potent Antitumor Efficacy and Enhanced Antitumor Immunity.
Journal of Medicinal Chemistry,
2022.
-
[20]
侯旭奔.
PTPRO is a therapeutic target and correlated with immune infiltrates in pancreatic cancer.
Journal of Cancer,
12,
7445-7453,
2021.