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方浩
-
教授
博士生导师
硕士生导师
- 主要任职：山东大学药学院药物化学研究所教授、博士生导师
- 性别：男
- 毕业院校：中国药科大学
- 学历：博士研究生毕业
- 学位：博士生
- 在职信息：在职
- 所在单位：药学院
- 入职时间： 2004-12-23
- 学科：药物化学
- 电子邮箱：phenopro@163.com
访问量：
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[1]
Chang, Yingjie.
Simultaneous inhibition of FLT3 and HDAC by novel 6-ethylpyrazine-2-Carboxamide derivatives provides.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY,
279,
2024.
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[2]
.
Development of a First-in-Class DNMT1/HDAC Inhibitor with Improved Therapeutic Potential and Potenti.
Journal of Medicianal Chemistry,
67,
16480-16504,
2024.
-
[3]
.
Design and synthesis of novel benzoic acid derivatives as striatal-enriched protein tyrosine phospha.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY,
283,
2024.
-
[4]
Liang, Tao.
Design, synthesis and biological evaluation of 3, 4-disubstituted-imidazolidine-2, 5-dione derivativ.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY,
221,
113526,
2021.
-
[5]
Liang, Tao.
Targeting histone deacetylases for cancer therapy: Trends and challenges.
ACTA PHARMACEUTICA SINICA B,
2023.
-
[6]
Zhao, Yunpeng.
Design, synthesis and bioactivity evaluations of 8-substituted-quinoli- ne-2-carboxamide derivatives.
Bioorganic & medicinal chemistry,
85,
2023.
-
[7]
.
Deciphering the Allosteric Activation Mechanism of SIRT6 Using Molecular Dynamics Simulations.
Journal of Chemical Information and Modeling,
63,
5896,
2023.
-
[8]
Liang, Tao.
Potential applications of BPFP1 in Bcl-2 protein quantification, carcinoma cell visualization, cell .
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY,
224,
113725,
2021.
-
[9]
.
Discovery of benzofuran-2-carboxylic acid derivatives as lymphoid tyrosine phosphatase (LYP) inhibit.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY,
258,
2023.
-
[10]
Liu, Meng.
Strategies to overcome drug resistance using SHP2 inhibitors..
ACTA PHARMACEUTICA SINICA B,
11,
3908-3924,
2021.
-
[11]
.
Fast Identification of Novel Lymphoid Tyrosine Phosphatase Inhibitors Using Target-Ligand Interactio.
Journal of Medicianal Chemistry,
57,
9309-9322,
2014.
-
[12]
Wen Li.
Recent advances in small molecule PROTACs for the treatment of cancer..
Curr Med Chem,
28,
4893-4909,
2020.
-
[13]
Liu, Meng.
Discovery of a Novel Benzimidazole Derivative Targeting Histone Deacetylase to Induce Ferroptosis an.
Journal of Medicianal Chemistry,
2024.
-
[14]
邱雪婷.
An in-line method for high-throughput screening of protein tyrosine phosphatase receptor type O inhi.
Journal of chromatography A,
1713,
2024.
-
[15]
.
Discovery of benzofuran-2-carboxylic acid derivatives as lymphoid tyrosine phosphatase (LYP) inhibit.
EUR J MED CHEM,
2023.
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[16]
聂义明.
Development of QSRR model for hydroxamic acids using PCA-GA-BP algorithm incorporated with molecular.
FRONTIERS IN CHEMISTRY,
2022.
-
[17]
Liang, Xiao.
Design, synthesis and biological evaluation of hydantoin derivatives as Mcl-1 selective inhibitors.
Bioorganic Chemistry,
121,
105643,
2022.
-
[18]
侯旭奔.
Discovery of Novel Src Homology-2 Domain-Containing Phosphatase 2 and Histone Deacetylase Dual Inhib.
Journal of Medicinal Chemistry,
2022.
-
[19]
侯旭奔.
PTPRO is a therapeutic target and correlated with immune infiltrates in pancreatic cancer.
Journal of Cancer,
12,
7445-7453,
2021.
-
[20]
梁翰之.
Structure-Based Design of 2-Aminopurine Derivatives as CDK2 Inhibitors for Triple-Negative Breast Ca.
FRONT PHARMACOL,
13,
864342,
2022.
