Journal:Angew. Chem. Int. Ed.
Abstract:Nanoscale curvature-dependent interactions are of
paramount importance in biological systems. Here, we report
that nanoscale curvature plays an important role in regulating
the chirality of self-assembled nanocomposites from chiral
organic molecules and achiral nanoparticles. Specifically, we
show that the supramolecular chirality of the nanocomposites
markedly depends on the nanoparticle curvature, where
small-sized nanoparticles of high curvature and large-sized
nanoparticles of low curvature lead to nanocomposites with
opposite chirality. Quantitative kinetic experiments and
molecular dynamics simulations reveal that nanoparticle
curvature plays a key role in promoting the pre-nucleation
oligomerization of chiral molecules, which consequently
regulates the supramolecular chirality of the nanocomposites.
We anticipate that this study will aid in rational design of an
artificial cooperative system giving rise to emergent assembling phenomena that can be surprisingly rich and often
cannot be understood by studying the conventional noncooperative systems.
First Author:巩彦君
Translation or Not:no
Date of Publication:2022-01-01
Included Journals:SCI
Date of Publication:2022-01-01