Paper Publications

• [1]  . Bacterial Biosynthesis of Nitrile-Containing Natural Products: Basis for Recognition of Diversified Substrates.  ACS Catal.,  14,  17780-17793, 2024. 
• [2]  Chang, Yingjie. Simultaneous inhibition of FLT3 and HDAC by novel 6-ethylpyrazine-2-Carboxamide derivatives provides therapeutic advantages in acute myelocytic leukemia.  EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY,  279,  2024. 
• [3]  . Development of a First-in-Class DNMT1/HDAC Inhibitor with Improved Therapeutic Potential and Potentiated Antitumor Immunity.  Journal of Medicianal Chemistry,  67,  16480, 2024. 
• [4]  . Design and synthesis of novel benzoic acid derivatives as striatal-enriched protein tyrosine phosphatase (STEP) inhibitors with neuroprotective properties.  EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY,  2024. 
• [5]  Liang, Tao. Design, synthesis and biological evaluation of 3, 4-disubstituted-imidazolidine-2, 5-dione derivatives as HDAC6 selective inhibitors..  EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY,  221,  113526, 2021. 
• [6]  Liang, Tao. Targeting histone deacetylases for cancer therapy: Trends and challenges.  ACTA PHARMACEUTICA SINICA B,  2023. 
• [7]  Zhao, Yunpeng. Design, synthesis and bioactivity evaluations of 8-substituted-quinoli- ne-2-carboxamide derivatives as novel histone deacetylase (HDAC) inhibitors.  Bioorganic & medicinal chemistry,  85,  2023. 
• [8]  . Deciphering the Allosteric Activation Mechanism of SIRT6 Using Molecular Dynamics Simulations.  Journal of Chemical Information and Modeling,  63,  5896, 2023. 
• [9]  Liang, Tao. Potential applications of BPFP1 in Bcl-2 protein quantification, carcinoma cell visualization, cell sorting and early cancer diagnosis.  EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY,  224,  113725, 2021. 
• [10]  . Discovery of benzofuran-2-carboxylic acid derivatives as lymphoid tyrosine phosphatase (LYP) inhibitors for cancer immunotherapy.  EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY,  258,  2023. 
• [11]  Liu, Meng. Strategies to overcome drug resistance using SHP2 inhibitors..  ACTA PHARMACEUTICA SINICA B,  11,  3908-3924, 2021. 
• [12]  . Fast Identification of Novel Lymphoid Tyrosine Phosphatase Inhibitors Using Target-Ligand Interaction-Based Virtual Screening.  Journal of Medicianal Chemistry,  57,  9309-9322, 2014. 
• [13]  Wen Li. Recent advances in small molecule PROTACs for the treatment of cancer..  Curr Med Chem,  28,  4893-4909, 2020. 
• [14]  Liu, Meng. Discovery of a Novel Benzimidazole Derivative Targeting Histone Deacetylase to Induce Ferroptosis and Trigger Immunogenic Cell Death.  Journal of Medicianal Chemistry,  2024. 
• [15]  邱雪婷. An in-line method for high-throughput screening of protein tyrosine phosphatase receptor type O inhibitors by capillary electrophoresis based on electrophoretically mediated microanalysis.  Journal of chromatography A,  1713,  2024.