刘冰玉教授
刘冰玉，教授，博士生导师，兼任山东免疫学会常务理事、山东免疫学会青工会副主任委员等职务。先后入选国家优青、山东省优青、全国博新计划、山东大学杰出中青年学者等人才支持计划。主要研究方向为：抗感染固有免疫信号转导调控机制研究，相关成果以第一或者通讯作者身份发表于Nat Immunol、Nat Commun、Cell Death Differ、Adv Sci、Autophagy、Curr Opin Immunol等国际顶级及权威免疫学期刊。作为项目负责人承担国家自然基金优秀青年金、国家自然基金面上项目、国家自然基金青年... More+
- [1] . Lipid droplets restrict phagosome formation in antifungal immunity. CELLULAR & MOLECULAR IMMUNOLOGY, 2025.
- [2] . E3 ubiquitin ligase TRIM31 alleviates dopaminergic neurodegeneration by promoting proteasomal degradation of VDAC1 in Parkinson's Disease model. Cell Death and Differentiation, 2024.
- [3] 赵贵民. TRIM26 alleviates fatal immunopathology by regulating inflammatory neutrophil infiltration during Candida infection. PLOS Pathogens, 20, 2024.
- [4] 刘峰. MAVS-loaded unanchored Lys63-linked polyubiquitin chains activate the RIG-I-MAVS signaling cascade. Cellular & Molecular Immunology, 20, 1186, 2023.
- [5] 陈恬. The nucleotide receptor STING translocates to the phagosomes to negatively regulate anti-fungal immunity. Immunity, 56, 1727, 2023.
- [6] . CD-NTase family member MB21D2 promotes cGAS-mediated antiviral and antitumor immunity. Cell Death and Differentiation, 30, 1-13, 2023.
- [7] 陈恬. The nucleotide receptor STING translocates to the phagosomes to negatively regulate anti-fungal immunity. Immunity, 1727, 2023.
- [8] 庄万欣. USP3 deubiquitinates and stabilizes the adapter protein ASC to regulate inflammasome activation. Cellular & Molecular Immunology, 2022.
- [9] . The protein arginine methyltransferase PRMT1 promotes TBK1 activation through asymmetric arginine methylation. cell reports, 36, 2021.
- [10] 李炎. The overexpression of Tipe2 in CRC cells suppresses survival while endogenous Tipe2 accelerates AOM/DSS induced-tumor initiation. Cell Death & Disease, 12, 2021.
- [11] 刘冰玉. The protein arginine methyltransferase PRMT9 attenuates MAVS activation through arginine methylation. NATURE COMMUNICATIONS, 2022.
- [12] 曾圣兰. The E3 ubiquitin ligase TRIM31 is involved in cerebral ischemic injury by promoting degradation of TIGAR. Redox Biology, 45, 2021.
- [13] 秦菲. Methyltransferase-Like Protein 14 Attenuates Mitochondrial Antiviral Signaling Protein Expression to Negatively Regulate Antiviral Immunity via N-6-methyladenosine Modification. Advanced Science, 8, 2021.
- [14] 宋慧. The E3 ubiquitin ligase TRIM31 attenuates NLRP3 inflammasome activation by promoting proteasomal degradation of NLRP3. NATURE COMMUNICATIONS, 2016.
- [15] 宋慧. The E3 ubiquitin ligase TRIM31 attenuates NLRP3 inflammasome activation by promoting proteasomal degradation of NLRP3. NATURE COMMUNICATIONS, 2016.
- [16] 宋慧. The E3 ubiquitin ligase TRIM31 attenuates NLRP3 inflammasome activation by promoting proteasomal degradation of NLRP3. NATURE COMMUNICATIONS, 2016.
- [17] 刘冰玉. USP5 attenuates NLRP3 inflammasome activation by promoting autophagic degradation of NLRP3. Autophagy, 2021.
- [18] 刘冰玉. Methyltransferase-Like Protein 14 Attenuates Mitochondrial Antiviral Signaling Protein Expression to Negatively Regulate Antiviral Immunity via N 6 -methyladenosine Modification. Advanced Science, 15, 2021.
- [19] 刘冰玉. TRIM26 positively regulates the inflammatory immune response through K11-linked ubiquitination of TAB1. Cell Death and Differentiation, 2021.
- [20] 侯金秀. USP18 positively regulates innate antiviral immunity by promoting K63-linked polyubiquitination of MAVS. NATURE COMMUNICATIONS, 12, 2021.