• 2009-06-01-2011-06-30
  山东大学
  人体解剖与组织胚胎学
• 2000-09-01-2003-07-01
  山东大学
  Biomedical Engineering
• 1995-09-01-2000-07-01
  山东大学
  Clinical Medicine

• 2003-07 — Now
  山东大学医学院

1. 基础医学类其他专业

(1)张艳敏. 对分课堂在组织学教学中的应用 .《解剖学杂志》 .2022 ,45 (6):573-575

(2)王立言. 聚苯乙烯纳米塑料暴露引发小鼠角膜氧化应激与线粒体依赖性凋亡 .中国组织化学与细胞化学杂志 .2025 ,34 (01):27

(3)苑辉卿. Cyclic bisbibenzyls induce growth arrest and apoptosis of Human Prostate Cancer PC3 cells .ACTA PHARMACOL SIN .2010 ,31 (5):609

(4)张艳敏. Downregulation of GRIM-19 promotes growth and migration of human glioma cells .CANCER SCIENCE .2011 ,102 (11):1991-1999

(5)王婧婧. 改良的动脉内皮细胞铺片技术-医学形态学与医学机能学的实验教学融合设计 .中国组织化学与细胞化学杂志 .2019 ,28 (6):564-568

(6)王子奇. The deubiquitinase cofactor UAF1 interacts with USP1 and plays an essential role in spermiogenesis .eScience .2024 (27)

(7)王立言. 医学电镜虚拟仿真实验教学系统的构建与应用 .中国组织化学与细胞化学杂志 .2023 ,32 (02):218

(8)王立言. 改良快速骨组织脱钙法在透射电镜样品制备中的应用 .中国组织化学与细胞化学杂志 .2022 ,31 (06):608

(9)王富武. 医学形态学实验教学改革的探索与实践 .基础医学教育 .2022 ,24 (06):409-411

(10) Deficiency of the Tmem232 Gene Causes Male Infertility with Morphological Abnormalities of the Sperm Flagellum in Mice .CELLS .2023 ,12 (12)

(11)刘倩. 翻转课堂在细胞信号转导课程中的探索 .《中国细胞生物学学报》 .2021 ,43 (08):1644-1649

(12)吴美玲. 转化医学共享平台大型仪器设备培训方法探索 .山东化工 .2021 ,50 (23):193-195

(13)郭雨霁. 翻转课堂教学模式在组织学实验数字化教学中的应用研究 .解剖学杂志 .2021 (1)

(14)郭雨霁. 基于思政育人目标的人体胚胎学“教-育-研”一体化教学改革的实践 .解剖学杂志 .2021 (4)

(15)王立言. 医学电镜技术系列化微课+翻转课堂实验教学初探 .《实验室科学》 .2022 ,25 (1):123

(16)郭雨霁. Blended learning model via small private online course improves active learning and academic performance of embryology .CLINICAL ANATOMY .2022 ,35 (2):211

(17)康宁. 线粒体靶向的载紫杉醇TPP-PEG-PE纳米胶束的体外评价及促肿瘤细胞凋亡研究 .中草药 .2018 (23)

(18)张向红. 离心沉淀法制备细胞透射电镜样品的技术改进 .解剖学杂志 .2021 ,第44卷 (第2期):159

(19)田蜜. Hepatic HuR protects against the pathogenesis of non-alcoholic fatty liver disease by targeting PTEN .Cell Death & Disease .2021 ,12 (3)

(20)刘珊杉. Smooth muscle-specific HuR knockout induces defective autophagy and atherosclerosis .Cell Death & Disease .2021 ,12 (4)

(21)王立言. 医学电镜数字化教学图库的建立与应用 .《解剖学杂志》 .2019 (2019.05.020)

(22)王立言. 依托组织学实验教学平台构建二维码电镜资源库的实践与思考 .中国组织化学与细胞化学杂志 .2020 (2020. 03. 016)

(23)王婧婧. 改良的动脉内皮细胞铺片技术— 医学形态学与医学 机能学的实验教学融合设计 .中国组织化学与细胞化学杂志 .2019 ,28 (6)

(24)李洪璇. Melatonin enhances atherosclerotic plaque stability by inducing prolyl-4-hydroxylase alpha 1 expression .Journal of Hypertension .2019 ,37 (5):964

(25)纪淑芳,纪淑芳. Maternal hyperglycemia disturbs neocortical neurogenesis via epigenetic regulation in C57BL/6J mice .Cell Death & Disease .2019 ,10

(26)王岩. Changes of Serum Brain-derived Neurotrophic Factor in Children with Obstructive Sleep Apnoea–Hypopnoea Syndrome following Adenotonsillectomy. .The journal of International Medical Research .2010 ,38 (6):1942

(27)李昊元. Melatonin Enhances Proliferation and Modulates Differentiation of Neural Stem Cells Via Autophagy in Hyperglycemia .STEM CELLS .2019 ,37 (4):504

(28)王立言. 透射电镜下小鼠精子的形成过程 .医 药 .2018 ,06 (03):235

(29)王立言. 骨组织快速脱钙制备透射电镜样品方法探讨 .医药 .2018 ,07 (01):216

(30)张向红. 建立新型电镜实验教学模式,提高实验教学质量 .解剖学杂志 .2018 (05)

(31)郭雨霁. 基于混合式翻转课堂教学模式的人体胚胎学教学初探 .中国组织化学与细胞化学杂志 .2018 (05)

(32)李静媛. Nicotine induces endothelial dysfunction and promotes atherosclerosis via GTPCH1 .Journal of Cellular and Molecular Medicine .2018 ,22 (11):5406

(33)Du, Zhanhui. Genome-wide transcriptional analysis of BRD4-regulated genes and pathways in human glioma U251 cells .international journal of oncology .2018 ,52 (5):1415

(34)秦小腾. Heterotrimeric G Stimulatory Protein alpha Subunit Is Required for Intestinal Smooth Muscle Contraction in Mice .Gastroenterology .2017 ,152 (5):1114

(35)孔静. Melatonin attenuates angiotensin II-induced abdominal aortic aneurysm through the down-regulation of matrix metalloproteinases .ONCOTARGET .2017 ,8 (9):14283

(36)Shangming Liu. Melatonin prevents neural tube defects in the offspring of diabetic pregnancy. .《J Pineal Research》 .2015 ,59 (4):508

(37)Dexiang Liu. Anti-inflammatory effects of fluoxetine in lipopolysaccharide(LPS)-stimulated microglial cells .Neuropharmacology .2011 ,61 (4):592

(38)潘燕. 脑淋巴液滞留对大鼠前额叶皮质区诱导型一氧化氮合成酶表达量的影响及羟基红花黄素A对 .《山东大学学报》（医学版） .2014 ,6 (52):7

(39)郭雨霁. Granulocyte colony-stimulating factor improves alternative activation of microglia under microenvironment of spinal cord injury .neuroscience .2013 (238):1

(40)郭雨霁. Sox11 promotes endogenous neurogenesis and locomotor recovery in mice spinal cord injury .Biochem Biophys Res Commun. .2014 ,446 (4):830

(41)郝爱军. Melatonin promotes proliferation and differentiation of neural stem cells subjected to hypoxia in vitro .Copenhagen : Munksgaard International Publishers .2011 ,51 (1):104

(42)Shangming Liu. High glucose induces apoptosis in embryonic neural progenitor cells by a pathway involving protein PKCδ .Cellular Signalling .2011 ,23 (8):1366

(43)郭雨霁. G-CSF promotes autophagy and reduces neural tissue damage after spinal cord injury in mice .LAB INVEST .2015 ,95 (12):1439-49

(44)郝爱军. Downregulation of GRIM-19 promotes growth and migration of human glioma cells. .Cancer Science .2011 ,102 (11):1991

(45)Shangming Liu. Bone morphogenetic protein？2 regulates the differentiation of nitrergic enteric neurons by modulating Smad1 signaling in slow transit constipation .Mol Med Rep .2015 ,12 (5)

(46)Dexiang Liu. Saturated fatty acids activate microglia via Toll-like receptor 4/NF-kB signalling .British Journal of Nutrition .2012 ,2012, 107(2): 229-241 (2):229

(47)郭雨霁. Granulocyte colony-stimulating factor improves neuron survival in experimental spinal cord injury by regulating nucleophosmin-1 expression .J Neurosci Res. .2014 ,92 (6):751

(48)王富武. Calcitonin promotes mouse pre-implantation development: involvement of calcium mobilization and P38 mitogen-activated protein kinase activation .Reproduction in Domestic Animals .2013 ,48 (3):382

(49)Shangming Liu. Expression profile of embryonic stem cell-associated genes Oct4, Sox2 and Nanog in human gliomas .Histopathology .2011 ,59 (4):763

(50)郝爱军. Expression of OCT4 pseudogenes in human tumours: lessons from glioma and breast carcinoma .The Journal of Pathology .2011 ,223 (5):672

(51)王婧婧. A novel effect of lobeline on vascular smooth muscle cell: inhibition of proliferation induced by endothelin-1 .PHARMAZIE .2007 ,62 (8):620

(52)郝爱军. Roles of activated astrocytes in bone marrow stromal cell proliferation and differentiation .neuroscience .2009 ,160 (2):319

(53)Shangming Liu. 心电图检测与辨识的人工神经网络方法 .实验室研究与探索 .2005 ,24 (11):15

(54)郭雨霁. 胚胎干细胞关键因子Nanog在人胶质瘤中的表达及意义 .《解剖学报》 .2013 ,44 :1

(55)张艳敏. Melatonin antagonizes hypoxia-mediated glioblastoma cell migration and invasion via inhibition of HIF-1α .Journal of pineal research .2013 ,55 (2):121

(56)李静媛. Nicotine induces endothelial dysfunction and promotes atherosclerosis via GTPCH1 .Journal of Cellular and Molecular Medicine .2018 ,22 (11):5406

(57)郝爱军. Melatonin promotes proliferation and differentiation of neural stem cells subjected to hypoxia in vitro .Copenhagen : Munksgaard International Publishers .2011 ,51 (1):104

(58)郝爱军. Downregulation of GRIM-19 promotes growth and migration of human glioma cells. .Cancer Science .2011 ,102 (11):1991

(59)郭雨霁. Granulocyte colony-stimulating factor improves neuron survival in experimental spinal cord injury by regulating nucleophosmin-1 expression .J Neurosci Res. .2014 ,92 (6):751

(60)郝爱军. Expression of OCT4 pseudogenes in human tumours: lessons from glioma and breast carcinoma .The Journal of Pathology .2011 ,223 (5):672

(61)王婧婧. A novel effect of lobeline on vascular smooth muscle cell: inhibition of proliferation induced by endothelin-1 .PHARMAZIE .2007 ,62 (8):620

(62)郭雨霁. 胚胎干细胞关键因子Nanog在人胶质瘤中的表达及意义 .《解剖学报》 .2013 ,44 :1

(63)张艳敏. Melatonin antagonizes hypoxia-mediated glioblastoma cell migration and invasion via inhibition of HIF-1α .Journal of pineal research .2013 ,55 (2):121

(64)李昊元. Melatonin Enhances Proliferation and Modulates Differentiation of Neural Stem Cells Via Autophagy in Hyperglycemia .STEM CELLS .2019 ,37 (4):504

(65)郝爱军. Roles of activated astrocytes in bone marrow stromal cell proliferation and differentiation .neuroscience .2009 ,160 (2):319

(66)郝爱军. Downregulation of GRIM-19 promotes growth and migration of human glioma cells. .Cancer Science .2011 ,102 (11):1991

(67)Du, Zhanhui. Genome-wide transcriptional analysis of BRD4-regulated genes and pathways in human glioma U251 cells .international journal of oncology .2018 ,52 (5):1415

(68)张艳敏. Melatonin antagonizes hypoxia-mediated glioblastoma cell migration and invasion via inhibition of HIF-1α .Journal of pineal research .2013 ,55 (2):121

(69)孔静. Melatonin attenuates angiotensin II-induced abdominal aortic aneurysm through the down-regulation of matrix metalloproteinases .ONCOTARGET .2017 , 8 (9):14283

(70)王富武. Calcitonin promotes mouse pre-implantation development: involvement of calcium mobilization and P38 mitogen-activated protein kinase activation .Reproduction in Domestic Animals .2013 ,48 (3):382

(71)王立言. 透射电镜下小鼠精子的形成过程 .医 药 .2018 ,06 (03):235

(72)王立言. 骨组织快速脱钙制备透射电镜样品方法探讨 .医药 .2018 ,07 (01):216

(73)郝爱军. Expression of OCT4 pseudogenes in human tumours: lessons from glioma and breast carcinoma .The Journal of Pathology .2011 ,223 (5):672

(74)潘燕. 脑淋巴液滞留对大鼠前额叶皮质区诱导型一氧化氮合成酶表达量的影响及羟基红花黄素A对 .《山东大学学报》（医学版） .2014 ,6 (52):7

(75)郭雨霁. 胚胎干细胞关键因子Nanog在人胶质瘤中的表达及意义 .《解剖学报》 .2013 ,44 :1

(76)郭雨霁. Granulocyte colony-stimulating factor improves alternative activation of microglia under microenvironment of spinal cord injury .neuroscience .2013 (238):1

(77)Dexiang Liu. Saturated fatty acids activate microglia via Toll-like receptor 4/NF-kB signalling .British Journal of Nutrition .2012 ,2012, 107(2): 229-241 (2):229

(78)张向红. 建立新型电镜实验教学模式,提高实验教学质量 .解剖学杂志 .2018 (05)

(79)郝爱军. Melatonin promotes proliferation and differentiation of neural stem cells subjected to hypoxia in vitro .Copenhagen : Munksgaard International Publishers .2011 ,51 (1):104

(80)王婧婧. A novel effect of lobeline on vascular smooth muscle cell: inhibition of proliferation induced by endothelin-1 .PHARMAZIE .2007 ,62 (8):620

(81)郭雨霁. G-CSF promotes autophagy and reduces neural tissue damage after spinal cord injury in mice .LAB INVEST .2015 ,95 (12):1439-49

(82)郭雨霁. Granulocyte colony-stimulating factor improves neuron survival in experimental spinal cord injury by regulating nucleophosmin-1 expression .J Neurosci Res. .2014 ,92 (6):751

(83)郭雨霁. Sox11 promotes endogenous neurogenesis and locomotor recovery in mice spinal cord injury .Biochem Biophys Res Commun. .2014 ,446 (4):830

(84)Dexiang Liu. Anti-inflammatory effects of fluoxetine in lipopolysaccharide(LPS)-stimulated microglial cells .Neuropharmacology .2011 ,61 (4):592

(85)郭雨霁. 基于混合式翻转课堂教学模式的人体胚胎学教学初探 .中国组织化学与细胞化学杂志 .2018 (05)

(86)秦小腾. Heterotrimeric G Stimulatory Protein alpha Subunit Is Required for Intestinal Smooth Muscle Contraction in Mice .Gastroenterology .2017 , 152 (5):1114

(87)李静媛. Nicotine induces endothelial dysfunction and promotes atherosclerosis via GTPCH1 .Journal of Cellular and Molecular Medicine .2018 ,22 (11):5406

(88)Shangming Liu. 心电图检测与辨识的人工神经网络方法 .实验室研究与探索 .2005 ,24 (11):15

(89)Shangming Liu. Bone morphogenetic protein？2 regulates the differentiation of nitrergic enteric neurons by modulating Smad1 signaling in slow transit constipation .Mol Med Rep .2015 ,12 (5)

(90)Shangming Liu. Melatonin prevents neural tube defects in the offspring of diabetic pregnancy. .《J Pineal Research》 .2015 ,59 (4):508

(91)Shangming Liu. Expression profile of embryonic stem cell-associated genes Oct4, Sox2 and Nanog in human gliomas .Histopathology .2011 ,59 (4):763

(92)Shangming Liu. High glucose induces apoptosis in embryonic neural progenitor cells by a pathway involving protein PKCδ .Cellular Signalling .2011 ,23 (8):1366

1. 一种细胞表型诊断系统、介质、设备及程序产品

2. 一种基于深度学习与高光谱图像的肿瘤早期识别系统

3. 半边莲生物碱在制备抗血管生成类药物中的应用

1. 血液多维成分高效质感分离装备系统开发与产业化, 2024-09-01-2027-08-31

2. 半边莲生物碱抗血管生成的应用研究, 2023-11-01-2026-10-30

3. 人脐带间充质干细胞移植联合基因疗法治疗帕金森病的应用基础研究, 2022-01-01-2024-12-31

4. “双一流”背景下高校大型设备公共技术平台建设模式研究与探索, 2021-08-04-2023-06-30

5. 蛋白的质谱鉴定, 2021-07-28-2021-09-30

6. 表观遗传修饰调控妊娠糖尿病致胚胎神经系统异常发育及其机制研究, 2020-12-12-2023-12-31

7. GB/T 16886.6《医疗器械生物学评价 第6部分：植入后局部反应》标准验证, 2020-06-10-2020-12-31

8. 妊娠糖尿病致胚胎神经干细胞过早分化及其机制研究, 2010-11-01-2013-11-01

9. NeuroLSD1介导的表观遗传调控网络在脊髓损伤Sox11再表达中作用的研究, 2019-07-08-2021-12-31

10. AMPK通路激活剂抗血管新生内膜增生的作用研究, 2019-10-28-2022-10-28

11. 神经退行性疾病机制研究, 2019-04-26-2022-06-30

12. 孕期肥胖致胚胎神经系统发育异常及其机制研究, 2014-08-15-2018-12-31

13. G-CSF对脑瘫内源性神经干细胞的作用及作用机制研究, 2011-01-01-2013-12-31

14. ILT4在非小细胞肺癌细胞中表达的作用及其上调VEGF-C表达的分子机制, 2013-08-15-2017-12-31

15. 缺血预处理诱导内质网应激保护肥大心肌的机制研究, 2010-01-01-2012-12-31

16. 利用条件基因敲除技术研究内源性H2S调控Shh通路对HIBD后新生小鼠海马神经再生的影响, 2016-08-17-2020-12-31

17. NOD2介导的免疫炎症反应在帕金森病中的作用及调控机制, 2015-08-17-2019-12-31

18. 人源化小鼠腘窝淋巴结试验模型构建及其在药物超敏反应机制研究中的应用, 2012-07-31-2015-07-31

19. 叶酸用于脑瘫治疗的实验研究, 2012-01-01-2014-12-31

20. 钙调神经磷酸酶参与低氧后处理对内质网应激诱导骨骼肌细胞损伤的保护作用及, 2011-07-01-2014-07-01

21. 蛋白H在神经发育中作用的研究, 2008-01-01-2010-12-31

22. 慢性间歇低氧环境中BDNF介导的海马突触可塑性调控机制的研究, 2018-04-01-2021-07-01

23. G-CSF经自噬对小鼠脊髓损伤内源性神经再生的作用及机制的研究, 2015-07-01-2017-12-31

24. 小胶质细胞对骨髓间充质干细胞迁移的影响及其机制探讨, 2012-07-31-2015-07-31

25. 半边莲生物碱防治动脉粥样硬化的机制研究及其有效成分筛选, 2010-11-01-2013-11-01

26. 携带转录因子Sox11的自组装IKVAV多肽纳米纤维对大鼠脊髓损伤修复的作用, 2010-10-01-2013-10-01

27. 妊娠糖尿病致神经管畸形发生机理的研究, 2007-01-01-2009-12-31

28. 肿瘤微环境中Tim-3调控CD8+ T细胞功能和耗竭的作用机制, 2016-08-17-2019-12-31

29. Sox19b在神经管发育缺陷中的新作用及机制研究, 2015-08-17-2019-12-31

30. 持续机械应力刺激对内淋巴囊上皮细胞免疫功能影响的研究, 2015-08-17-2019-12-31

31. 小分子化合物对胚胎神经干细胞作用的新发现及机制研究, 2014-08-15-2015-12-31

32. 孕期肥胖致胚胎神经干细胞异常分化及其机制研究, 2013-10-01-2016-10-31

33. 神经细胞中信号转导分子stat3的调控与功能分析, 2004-12-10-2006-12-30

34. 妊娠糖尿病致胚胎神经损伤作用机理的研究, 2007-01-01-2009-12-30

35. 叶酸对脑瘫内源性神经干细胞的作用及作用机制研究, 2012-01-01-2015-12-31

36. Oct4在脑肿瘤干细胞发生中的作用及其机制的研究, 2008-12-01-2011-12-31

37. 半边莲单体山梗菜碱防治动脉粥样硬化的实验研究, 2009-01-01-2011-12-30

38. 蛋白H在神经元蛋白棕榈酰化中作用的研究, 2007-12-01-2010-12-31

39. 褪黑素对缺血缺氧性脑病内源性神经干细胞的作用及机制研究, 2012-01-01-2014-12-01

40. 妊娠糖尿病致胚胎神经系统异常发育及其机制研究, 2012-01-01-2014-12-31