Hits:
Institution:药学院
Title of Paper:Design, synthesis, and antiviral evaluation of novel hydrazone-substituted thiophene[3,2-d]pyrimidine derivatives as potent human immunodeficiency virus-1 inhibitors
Journal:Chemical Biology & Drug Design
First Author:汪昭
All the Authors:展鹏,刘新泳
Document Code:2BBCC8DD65164DBC84E6EE9F3BF50435
Volume:92
Issue:6
Page Number:2009
Translation or Not:No
Date of Publication:2018-12
Release Time:2019-10-04
Prev One:Exploiting the Tolerant Region I of the Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI) Binding Pocket: Discovery of Potent Diarylpyrimidine-Typed HIV-1 NNRTIs against Wild-Type and E138K Mutant Virus with Significantly Improved Water Solubility and Favorable Safety Profiles
Next One:Structure-Based Optimization of N-Substituted Oseltamivir Derivatives as Potent Anti-Influenza A Virus Agents with Significantly Improved Potency against Oseltamivir-Resistant N1-H274Y Variant