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Scientific Research
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Target-based drug design strategies to overcome resistance to antiviral agents: opportunities and challenges.
DRUG RESISTANCE UPDATES,
73,
2024.
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Revolutionizing viral disease treatment: Phase separation and lysosome/exosome targeting as new areas and new paradigms for antiviral drug research.
Drug Discov Today.,
29,
2024.
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Identification of a small-molecule Tim-3 inhibitor to potentiate T cell-mediated antitumor immunotherapy in preclinical mouse models.
SCIENCE TRANSLATIONAL MEDICINE,
15,
2024.
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SARS-CoV-2 NSP5 and N protein counteract the RIG-I signaling pathway by suppressing the formation of stress granules.
SIGNAL TRANSDUCTION AND TARGETED THERAPY,
2023.
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黄伯世.
Structure-Based Design and Discovery of Pyridyl-Bearing Fused Bicyclic HIV-1 Inhibitors: Synthesis, Biological Characterization, and Molecular Modeling Studies.
Journal of Medicianal Chemistry,
64,
13604-13621,
2023.
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黄伯世.
First discovery of a potential carbonate prodrug of NNRTI drug candidate RDEA427 with submicromolar inhibitory activity against HIV-1 K103N/Y181C double mutant strain.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,
28,
1348,
2023.