location: Current position: Home >> Scientific Research >> Paper Publications

Strategies for the Discovery of Target-Specifific or Isoform-Selective Modulators

Hits:

Affiliation of Author(s):药学院

Journal:Journal of Medicinal Chemistry

All the Authors:zhanpeng

First Author:liuxinyong

Indexed by:Unit Twenty Basic Research

Document Code:E331779E89B140EE98E97C9BD9B2D63D

Translation or Not:no

Date of Publication:2015-06-18

Pre One:Exploiting the Tolerant Region I of the Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI) Binding Pocket: Discovery of Potent Diarylpyrimidine-Typed HIV-1 NNRTIs against Wild-Type and E138K Mutant Virus with Significantly Improved Water Solubility and Favorable Safety Profiles

Next One:Structure-Based Optimization of N-Substituted Oseltamivir Derivatives as Potent Anti-Influenza A Virus Agents with Significantly Improved Potency against Oseltamivir-Resistant N1-H274Y Variant