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Fused heterocycles bearing bridgehead nitrogen as potent HIV-1 NNRTIs. Part 3: Optimization of [1,2,4]triazolo[1,5-a]pyrimidine core via structure-based and physicochemical property-driven approaches

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Affiliation of Author(s):药学院

Journal:EUR J MED CHEM

All the Authors:liuxinyong,zhanpeng,liuhuiqing

First Author:liuxinyong

Document Code:lw-171573

Volume:92C

Page Number:754

Translation or Not:no

Date of Publication:2015-01-22

Pre One:Synthesis and biological evaluation of a series of 2-((1-substituted-1H-1,2,3-triazol-4-yl)methylthio)-6-(naphthalen-1-ylmethyl)pyrimidin-4(3H)-one as potential HIV-1 inhibitors

Next One:Fused heterocycles bearing bridgehead nitrogen as potent HIV-1 NNRTIs. Part 4: Design, synthesis and biological evaluation of novel imidazo[1,2-a]pyrazines