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Identification of novel potent HIV-1 inhibitors by exploiting the tolerant regions of the NNRTIs binding pocket

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Affiliation of Author(s):药学院

Journal:European Journal of Medicinal Chemistry

First Author:孙彦莹

Indexed by:Unit Twenty Basic Research

Document Code:A9B63B9A92324DFEB3F82320DC1DF5D1

Volume:214

Translation or Not:no

Date of Publication:2021-03-15

Pre One:Exploiting the tolerant region I of the non-nucleoside reverse transcriptase inhibitor (NNRTI) binding pocket. Part 2: Discovery of diarylpyrimidine derivatives as potent HIV-1 NNRTIs with high Fsp(3) values and favorable drug-like properties

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