Current position: Home >> Scientific Research >> Paper Publications

Identification of novel potent HIV-1 inhibitors by exploiting the tolerant regions of the NNRTIs binding pocket

Hits:

Institution:药学院

Title of Paper:Identification of novel potent HIV-1 inhibitors by exploiting the tolerant regions of the NNRTIs binding pocket

Journal:EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

First Author:孙彦莹

Document Code:A9B63B9A92324DFEB3F82320DC1DF5D1

Volume:214

Translation or Not:No

Date of Publication:2021-03

Release Time:2021-05-30

Prev One:Exploiting the tolerant region I of the non-nucleoside reverse transcriptase inhibitor (NNRTI) binding pocket. Part 2: Discovery of diarylpyrimidine derivatives as potent HIV-1 NNRTIs with high Fsp(3) values and favorable drug-like properties

Next One:Novel indolylarylsulfone derivatives as covalent HIV-1 reverse transcriptase inhibitors specifically targeting the drug-resistant mutant Y181C