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李祥乾

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助理研究员

性别：男

在职信息：在职

所在单位：微生物技术研究院

入职时间：2019-09-23

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当前位置中文主页 >> 科学研究 >> 论文成果

[1] 孙昊. Small Molecule SHP2 Inhibitor LXQ-217 affects Lung Cancer Cell Proliferation in Vitro and in Vivo. Chemistry & Biodiversity, 2024.
[2] . Design of Selective PARP-1 Inhibitors and Antitumor Studies. Journal of Medicianal Chemistry, 2024.
[3] 张众. Visible-Light-Promoted Oxy-difluoroalkylation of Aryl Alkynes for the Synthesis of beta-Fluoroenones. Advanced Synthesis & Catalysis, 363, 3348, 2021.
[4] 王泽敏. Photo-induced versatile aliphatic C–H functionalization via electron donor–acceptor complex. science bulletin, 2023.
[5] . Advances in Development of Selective Antitumor Inhibitors That Target PARP？1. J. Med. Chem. , 66, 16464, 2023.
[6] . MNK, mTOR or eIF4E-selecting the best anti-tumor target for blocking translation initiation. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 260, 2023.
[7] 李晓伟. Nickel-catalyzed stereoselective reductive cross-coupling of <i>gem</i>-difluoroalkenes with alkenyl. 化学通讯, 59, 6893, 2023.
[8] 李晓伟. Nickel-Catalyzed Stereoselective Cascade C-F Functionalizations of gem-Difluoroalkenes. ACS Catalysis, 2023.
[9] 张众. <i>S</i>-Trifluoromethyl thioesters as bifunctional reagents for acyl-trifluoromethylthiolation of a. GREEN CHEMISTRY, 25, 2723, 2023.
[10] 李晓伟. Nickel-Catalyzed Stereoselective Cascade C-F Functionalizations of gem-Difluoroalkenes. ACS Catalysis, 13, 2135, 2023.
[11] 张众. S-Trifluoromethyl thioesters as bifunctional reagents for acyl-trifluoromethylthiolation of alkenes . GREEN CHEMISTRY, 2723, 2023.
[12] 刘瑞华. Visible light–initiated radical 1,3-difunctionalization of β,γ-unsaturated ketones. Science Advances, 8, 2022.
[13] 史婷. Bioactivity-Guided Screening of Antimicrobial Secondary Metabolites from Antarctic Cultivable Fungus. Marine Drugs, 20, 2022.
[14] 虞燕燕. Self-developed NF-κB inhibitor 270 protects against LPS-induced acute kidney injury and lung injury. Biomedicine & Pharmacotherapy, 147, 112615, 2022.
[15] 李超. Highly Selective Protein Tyrosine Phosphatase Inhibitor, 2,2 ',3,3 '-Tetrabromo-4,4 ',5,5 '-tetrahyd. Molecular Pharmaceutics, 1839, 2019.
[16] 李祥乾. Rational Multitargeted Drug Design Strategy from the Perspective of a Medicinal Chemist. Journal of Medicinal Chemistry, 10581, 2021.
[17] 史晓琳. Palladium-Catalyzed Remote C-H Phosphonylation of Indoles at the C4 and C6 Positions by a Radical Ap. Angew. Chem. Int. Ed, 13871, 2021.
[18] 戴佳佳. Toward a Treatment of Cancer: Design and In Vitro/In Vivo Evaluation of Uncharged Pyrazoline Derivat. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES , 23, 2022.
[19] 李宇修. Highly E-Selective Synthesis of alpha-Fluoro-beta-arylalkenyl Sulfones from gem-Difluoroalkenes with. The Journal of Organic Chemistry, 6983, 2021.
[20] 史大永. Palladium-Catalyzed Remote C-H Phosphonylation of Indoles at the C4 and C6 Positions by a Radical Ap. Angew. Chem. Int. Ed, 60, 13871, 2021.

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