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李祥乾

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助理研究员

性别：男

在职信息：在职

所在单位：微生物技术研究院

入职时间：2019-09-23

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当前位置中文主页 >> 科学研究 >> 论文成果

[1] . Design, synthesis and activity evaluation of dual-target inhibitors against papain-like and main pro. JOURNAL OF ADVANCED RESEARCH, 2025.
[2] 秦宏云. Photoinduced Bartoli Indole Synthesis by the Oxidative Cleavage of Alkenes with Nitro(hetero)arenes. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2024.
[3] 单文龙. Visible light-induced cobalt-catalyzed 1,3-diphosphination of alkenes. GREEN CHEMISTRY, 2024.
[4] 石聪. Radical Addition-Enabled C-C σ-Bond Cleavage/Reconstruction to Access Functional Indanones: Total S. organic letters, 2024.
[5] 石聪. Anaerobic 1,2-/1,3-Hydroxytrifluoromethylation of Unactivated Alkenes Enabled by Photoexcited Nitroa. Organic letters, 2025.
[6] 袁磊峰. Organometallic Reagent-Free Iron-Catalyzed C-Cl Bond Activation of Aryl Chlorines. ORGANIC LETTERS, 27, 3725-3730, 2025.
[7] . Allosteric inhibition of PTP1B by bromocatechol-chalcone derivatives. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 117053, 2024.
[8] 孙昊. Small Molecule SHP2 Inhibitor LXQ-217 affects Lung Cancer Cell Proliferation in Vitro and in Vivo. Chemistry & Biodiversity, 2024.
[9] . Design of Selective PARP-1 Inhibitors and Antitumor Studies. Journal of Medicianal Chemistry, 2024.
[10] 张众. Visible-Light-Promoted Oxy-difluoroalkylation of Aryl Alkynes for the Synthesis of beta-Fluoroenones. Advanced Synthesis & Catalysis, 363, 3348, 2021.
[11] 王泽敏. Photo-induced versatile aliphatic C–H functionalization via electron donor–acceptor complex. science bulletin, 2023.
[12] . Advances in Development of Selective Antitumor Inhibitors That Target PARP？1. J. Med. Chem. , 66, 16464, 2023.
[13] . MNK, mTOR or eIF4E-selecting the best anti-tumor target for blocking translation initiation. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 260, 2023.
[14] 李晓伟. Nickel-catalyzed stereoselective reductive cross-coupling of <i>gem</i>-difluoroalkenes with alkenyl. 化学通讯, 59, 6893, 2023.
[15] 李晓伟. Nickel-Catalyzed Stereoselective Cascade C-F Functionalizations of gem-Difluoroalkenes. ACS Catalysis, 2023.
[16] 张众. <i>S</i>-Trifluoromethyl thioesters as bifunctional reagents for acyl-trifluoromethylthiolation of a. GREEN CHEMISTRY, 25, 2723, 2023.
[17] 李晓伟. Nickel-Catalyzed Stereoselective Cascade C-F Functionalizations of gem-Difluoroalkenes. ACS Catalysis, 13, 2135, 2023.
[18] 张众. S-Trifluoromethyl thioesters as bifunctional reagents for acyl-trifluoromethylthiolation of alkenes . GREEN CHEMISTRY, 2723, 2023.
[19] 刘瑞华. Visible light–initiated radical 1,3-difunctionalization of β,γ-unsaturated ketones. Science Advances, 8, 2022.
[20] 史婷. Bioactivity-Guided Screening of Antimicrobial Secondary Metabolites from Antarctic Cultivable Fungus. Marine Drugs, 20, 2022.

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