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Discovery of 4,6-O-Thenylidene-beta-D-glucopyranoside-(2 ''-acetamido, 3 ''-acetyl-di-S-5-fluorobenzothizole/5-fluorobenzoxazole)-4 '-demethylepipodophyllotoxin as Potential Less Toxic Antitumor Candidate Drugs by Reducing DNA Damage and Less Inhibition of PI3K

发布时间：2021-04-29 点击次数：

所属单位：微生物技术研究院
论文名称：Discovery of 4,6-O-Thenylidene-beta-D-glucopyranoside-(2 ''-acetamido, 3 ''-acetyl-di-S-5-fluorobenzothizole/5-fluorobenzoxazole)-4 '-demethylepipodophyllotoxin as Potential Less Toxic Antitumor Candidate Drugs by Reducing DNA Damage and Less Inhibition of PI3K
发表刊物：《Journal of Medicinal Chemistry》
第一作者：Cheng, Jie
论文类型：基础研究
论文编号：6F0E83F4B08D4E42B5439DD8A10AD9D4
卷号：63
期号：6
页面范围：2877
是否译文：否
发表时间：2020-03-26
发表时间：2020-03-26

上一条：A CRISPR/Cas9-mediated, homology-independent tool developed for targeted genome integration in Yarrowia lipolytica

下一条：A novel podophyllotoxin derivative with higher anti-tumor activity produced via 4 '-demethylepipodophyllotoxin biotransformation by Penicillium purpurogenum

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论文成果

Discovery of 4,6-O-Thenylidene-beta-D-glucopyranoside-(2 ''-acetamido, 3 ''-acetyl-di-S-5-fluorobenzothizole/5-fluorobenzoxazole)-4 '-demethylepipodophyllotoxin as Potential Less Toxic Antitumor Candidate Drugs by Reducing DNA Damage and Less Inhibition of PI3K