Song Fengling
Professor
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Personal Information:
  • Name (English):
    Song Fengling
  • Name (Pinyin):
    Song Fengling
  • E-Mail:
    songfl@sdu.edu.cn
  • Date of Employment:
    2019-02-01
  • School/Department:
    Shandong University
  • Education Level:
    Postgraduate (Postdoctoral)
  • Gender:
    Male
  • Contact Information:
    songfl@sdu.edu.cn
  • Degree:
    Doctoral Degree in Engineering
  • Status:
    Employed
  • Alma Mater:
    Dalian University of Technology
  • Supervisor of Doctorate Candidates
  • Supervisor of Master's Candidates
Academic Honor:

2012    Winner of National Outstanding Youth Foundation;
2013    Candidate of the Program for New Century Excellent Talents of the Ministry of Education;
Biography

Prof. Dr. Fengling Song obtained his PhD degree from Dalian University of Technology in 2005. Then he did postdoc research at Wayne State University and University of Pittsburgh in USA from 2006-2009. From 2009 to 2023, he was a professor at State Key Laboratory of Fine Chemicals of Dalian University of Technology. Now he is working at  Institute of Frontier Chemistry, School of Chemistry and Chemical Engineering, Shandong University in Qingdao.  


Research Interests:

l   Nanophotosensitizers for PDT and PTT

l   Theranostic photosensizers based on organic compounds with Thermally Activated Delayed Fluorescence 

l   Fluorogenic Chemosensors for Hazard Chemicals.

l  Near-Infrared Fluorescent probes for Bioimaging

 

Representive Publications:

1.     Chen, Wenlong; Wang, Zehui; Tian, Mingyu; Hong, Gaobo; Wu, Yingnan; Sui, Mengzhang; Chen, Miaomiao; An, Jing; Song, Fengling;* Peng, Xiaojun. Integration of TADF Photosensitizer as “Electron Pump” and BSA as “Electron Reservoir” for Boosting Type I Photodynamic Therapy. J. Am. Chem. Soc. 2023, 145, 8130–8140.An, Jing; Tang, Shanliang; Hong, Gaobo; Chen, Wenlong; Chen, Miaomiao; Lv, Shibo; Song, Jitao Dapeng, Liu; Li, Zhiliang; Peng, Xiaojun; Song, Fengling;* Zheng, Wen-heng.* An Unexpected Strategy to Alleviate Hypoxia Limitation of Photodynamic Therapy by Biotination of Photosensitizers. Nature Communications, 2022, 13, 2225.

2.     Xiong, Xiaoqing; Song, Fengling;* Wang, Jingyun; Zhang, Yukang; Xue, Yingying; Sun, Liangliang; Jiang, Na; Gao, Pan; Tian, Lu; Peng, Xiaojun. Thermally Activated Delayed Fluorescence of Fluorescein Derivative for Time-Resolved and Confocal Fluorescence Imaging. J. Am. Chem. Soc. 2014, 136, 95909597.

3.     Song, Fengling; Watanabe, Shuji; Floreancig, Paul E.; Koide, Kazunori.* Oxidation-resistant fluorogenic probe for mercury based on alkyne oxymercuration. J. Am. Chem. Soc. 2008, 130, 16460–16461.

4.     Song, Fengling; Garner, Amanda L; Koide, Kazunori.* A highly sensitive fluorescent sensor for palladium based on the allylic oxidative insertion mechanism. J. Am. Chem. Soc. 2007, 129, 12354–12355.

5.     Peng, Xiaojun;* Song, Fengling; Lu, Erhu; Wang, Yanan; Zhou, Wei; Fan, Jiangli; Gao, Yunling. Heptamethine cyanine dyes with a large stokes shift and strong fluorescence: A paradigm for excited-state intramolecular charge transfer. J. Am. Chem. Soc. 2005, 127, 4170-4171.


Publications:

1.       Chen, Wenlong; Wang, Zehui; Tian, Mingyu; Du, Jianjun; Hong, Gaobo; Song, Fengling;* Peng, Xiaojun. Self-Assembly-Integrated Tumor Targeting and Electron Transfer Programming Towards Boosting Tumor Type I Photodynamic Therapy. Chem. Sci., 2024, ASAP.

2.       Chen, Wenlong; Wang, Zehui; Tian, Mingyu; Du, Jianjun; Hong, Gaobo; Song, Fengling;* Peng, Xiaojun. Space-Arranged Intramolecular Modular Assembled Dyad as Superior-Performance “Superoxide Anion Engine” for Boosting Photodynamic Therapy. ACS Materials Lett., 2024, 6, 2350-2359.

3.       Sun, Han; Li, Lukun; Guo, Ruihua; Wang, Zhe; Guo, Yanhui; Li, Zhiliang;* Song, Fengling.* Suppressing ACQ of molecular photosensitizers by distorting the conjugated-plane for enhanced tumor photodynamic therapy. Chem. Sci., 2024, 20, 606-615.

4.       Lv, Shibo; Wang,Bo; Wu, Yingnan; Zhang, Ruiling; Feng, Erting; Liu, Tianyu; Xie, Xiangyu; Jiang, Jiaru; Hou, Xincan; Liu,Dapeng;* Song, Fengling.* Configuration-mediated excited-state energy dissipation in metal-bridged dimeric D-A fluorophores for enhanced photothermal therapy. Acta Biomaterialia., 2024, 174, 400-411.

5.       Hao, Caiqing; Shao, Yutong; Tian, Jiarui; Song, Jitao;* Song, Fengling.* Dual-Responsive Hollow Mesoporous Organosilicon Nanocarriers for Photodynamic Therapy. Journal of Colloid and Interface Science 2024, 659, 582-593.

6.       Shao, Yutong; Hao, Caiqing; Guo, Yanhui; Song, Jitao;* Song, Fengling.* Stable Hybrid Nanocapsules with Gold Nanorods and Cyanine Dyes for Near-Infrared Photothermal Ablation of Subcutaneous Tumor. Adv. Therap. 2023, 6, 2300066.

7.       Guo, Yanhui; Li, Lukun; Huang, Shuheng;* Sun, Han; Shao, Yutong; Li, Zhiliang;* Song, Fengling.* Exploring Linker-Group-Guided Self-Assembly of Ultrathin 2D Supramolecular Nanosheets in Water for Synergistic Cancer Phototherapy. ACS Applied Materials & Interfaces 2023, 15, 54851–54862.

8.       Shao, Yutong; Luan, Yanfei; Hao, Caiqing; Song, Jitao;* Li, Li;* Song, Fengling.* Antimicrobial protection of two controlled release silver nanoparticles on simulated silk cultural relic. Journal of Colloid And Interface Science 2023, 652, 901–911.

9.       Sun, Qianqian; Chen, Weilin; Wang, Man; Zheng, Pan; Gao, Minghong;* Song, Fengling,* Li, Chunxia. * A “Chase and Block” Strategy for Enhanced Cancer Therapy with Hypoxia-Promoted Photodynamic Therapy and Autophagy Inhibition Based on Upconversion Nanocomposites. Adv. Healthcare Mater., 2023, 12, 2301087.

10.    Wu, Jingxi; Shang, Jingjing; An, Jing; Chen, Wenlong; Hong, Gaobo; Hou, Haoran; Zheng, Wen-Heng;* Song, Fengling;* Peng, Xiaojun. Jointly Depleting Glutathione based on Self-assembled Nanomicelles for Enhancing Photodynamic Therapy. ChemBioChem, 2023, 24, e202200323.

11.    Hong, Gaobo; Wu, Yingnan; An, Jing; Chen, Wenlong; Song, Fengling;* Peng, Xiaojun. A TADF-based purely organic heterogeneous photocatalyst with hydrophobic domains for efficient oxidation of sulfide into sulfoxide in water. Sustainable Energy & Fuels. 2023, 145, 8130–8140.

12.    Shao, Yutong; Chen, Miaomiao; Chen, Miaomiao; Wang, Zehui; Sui, Mengzhang; Tian, Mingyu; Wu, Yingnan; Song, Jitao;* Ji, Debin;* Song, Fengling.* Integration of Activation by Hypoxia and Inhibition Resistance of Tumor cells to Apoptosis for Precise and Augmented Photodynamic Therapy. Adv. Healthcare Mater., 2023, 12, 2300503.

13.    Peng, Lekai; Chen, Wenlong; Hou, Haoran; Tian, Mingyu; Song, Fengling;* Zheng, Wen-Heng;* Peng, Xiaojun. Red-to-near-infrared self-reporting photosensitizers with high photostability for photodynamic therapy. Dyes & Pigments. 2023, 217, 111426.

14.    Chen, Wenlong; Wang, Zehui; Tian, Mingyu; Hong, Gaobo; Wu, Yingnan; Sui, Mengzhang; Chen, Miaomiao; An, Jing; Song, Fengling;* Peng, Xiaojun. Integration of TADF Photosensitizer as “Electron Pump” and BSA as “Electron Reservoir” for Boosting Type I Photodynamic Therapy. J. Am. Chem. Soc. 2023, 145, 8130–8140.

15.    Lv, Fangyuan; Feng, Erting; Lv, Shibo; Liu, Dapeng;* Song, Fengling;* Metal-Coordination-Mediated H-Aggregates of Cyanine Dyes for Effective Photothermal Therapy. Chem. Eur. J. 2023, 29, e202301483

16.    Tian, Mingyu; Chen, Wenlong; Hong, Gaobo; Chen, Miaomiao; Song, Fengling;* Zheng, Wen-Heng;* Peng, Xiaojun. Efficient Photodynamic Therapy Nanocarriers with Oxygen Saving and Smart ReleasingTranslocating Properties. ACS Materials Letters 2023, 5, 1922-1928.

17.    Sun, Han; Guo, Ruihua; Guo, Yanhui; Song, Jitao; Li, Zhiliang;* Song, Fengling.* Boosting Type‑I and Type-II ROS Production of Water-Soluble Porphyrin for Efficient Hypoxic Tumor Therapy. Mol. Pharmaceutics, 2023, 20, 606-615

18.    Wu, Yingnan; Zhao, Yanliang; Hou, Haoran; Hong, Gaobo; Guo, Hanhui; Zhang, Ruiling; Chen, Wenlong; Tian, Jiarui; Lv, Shibo; Wang, Honglei; Wang, Meishan;* Wu, Chenyu;* Song, Fengling.* Oxygen-Insensitive Delayed Fluorescence Based on Singlet Manifold. Advanced Optical Materials, 2023, 11, 2202413.

19.    Lv, Fangyuan; Fan, Xiaoxue; Liu, Dapeng;* Song, Fengling;* Photothermal agents based on small organic fluorophores with intramolecular motion. Acta Biomaterialia 2022, 149, 16-29.

20.    Feng, Erting; Liu, Yuhan; Lv, Shibo; Dapeng, Liu;* Huang, Shuheng; Li, Zhiliang; Song, Fengling.* Fine-Tuning Cu (II)-Induced Self-Assembly of Hydrophilic Cyanine Dyes for Enhanced Tumor Photothermal Therapy. Adv. Funct. Mater., 2022,32, 2209258.

21.    Lv, Shibo; Liu, Yuhan; Zhao, Yanliang; Fan, Xiaoxue; Lv, Fangyuan; Feng, Erting; Dapeng, Liu;* Song, Fengling.* Rational design of a small organic photosensitizer for NIR-I imaging-guided synergistic photodynamic and photothermal therapy. Biomater. Sci., 2022, 10, 4785-4795.

22.    Jin, Lin; Miao, Yuyang; Dapeng, Liu;* Song, Fengling.* Fe/Mn-Porphyrin Coordination Polymer Nanoparticles for Magnetic Resonance Imaging (MRI) Guided-Combination Therapy between Photodynamic Therapy and Chemodynamic Therapy. ChemistrySelect, 2022, 7, e202104366.

23.    Guo, Yanhui; Huang, Shuheng; Sun, Han; Wang, Zhe; Shao, Yutong; Li, Lukun; Li, Zhiliang;* Song, Fengling.*  Tuning the aqueous self-assembly of porphyrins by varying the number of cationic side chains. J. Mater. Chem. B, 2022, 105, 5968–5975.

24.    Sun, Jinghan; Feng, Erting; Shao, Yutong; Lv, Fangyuan; Wu, Yingnan; Tian, Jiarui; Sun, Han; Song, Fengling.* A selenium-substituted heptamethine cyanine photosensitizer for near-infrared photodynamic therapy. ChemBioChem, 2022, 23, e202200421.

25.    Wang, Donghui; Hou, Haoran; Chen, Wenlong; Wu, Yingnan; Peng, Xiaojun; Song, Fengling.* A turn-on fluorescent probe for palladium(II) detection with a large Stokes shift and lysosomes-targeting ability. Tetrahedron Letters, 2022, 102,153932.

26.    Chen, Miaomiao; Zhao, Shuju; Zhu, Jialong; Feng, Erting; Lv, Fangyuan; Chen, Wenlong; Lv, Shibo; Wu, Yingnan; Peng, Xiaojun; Song, Fengling.* Open-Source and Reduced-Expenditure Nanosystem with ROS Self-Amplification and Glutathione Depletion for Simultaneous Augmented Chemodynamic/Photodynamic Therapy. ACS Applied Materials & Interfaces 2022, 14, 20682-20692.

27.    An, Jing; Tang, Shanliang; Feng, Erting; Tian, Mingyu; Chen, Wenlong; Chen, Miaomiao; Hong, Gaobo; Peng, Xiaojun; Song, Fengling.* Naphthofluorescein-Based Organic Nanoparticles with Superior Stability for Near-Infrared Photothermal Therapy. Nanoscale, 2022, 14, 10051–10059.

28.    An, Jing; Tang, Shanliang; Hong, Gaobo; Chen, Wenlong; Chen, Miaomiao; Lv, Shibo; Song, Jitao Dapeng, Liu; Li, Zhiliang; Peng, Xiaojun; Song, Fengling;* Zheng, Wen-heng.* An Unexpected Strategy to Alleviate Hypoxia Limitation of Photodynamic Therapy by Biotinylation of Photosensitizers. Nature Communications, 2022, 13, 2225.

29.    Tian, Mingyu; Chen, Wenlong; Wu, Yingnan; An, Jing; Hong, Gaobo; Chen, Miaomiao; Song, Fengling;* Zheng, Wen-heng;* Peng, Xiaojun. Liposome-Based Nanoencapsulation of a Mitochondria-Stapling Photosensitizer for Efficient Photodynamic Therapy. ACS Applied Materials & Interfaces 2022, 14, 12050-12058.

30.    Zhao, Yanliang; Wu,Yingnan; Chen, Wenlong; Zhang, Ruiling; Hong, Gaobo; Tian, Jiarui; Wang, Honglei; Zheng, Daoyuan; Zhou, Wu, Chenyu; Jiang, Xiao; Huo, Xinming; Sun, Lei;*; Deng, Weiqiao; Han, Keli; Song, Fengling.* The Second Excited Triplet−State Facilitates TADF and Triplet−Triplet Annihilation Photon Upconversion via a Thermally Activated Reverse Internal Conversion. Advanced Optical Materials, 2022,10, 2102275.

31.    Feng, Erting; Jiao, Long; Tang, Shanliang; Chen, Miaomiao; Lv, Shibo; Dapeng, Liu; Song, Jitao; Peng, Xiaojun; Song, Fengling.* Anti-Photobleaching Cyanine-Based Nanoparticles with Simultaneous PET and ACQ Effects for Improved Tumor Photothermal Therapy. Chemical Engineering Journal, 2022, 432, 134355.

32.    Chen, Shuang; Liu, Yongzhuo; Liang, Ri; Hong, Gaobo; An, Jing; Peng, Xiaojun; Zheng, Wen-heng;* Song, Fengling.* Self-assembly of amphiphilic peptides to construct activatable nanophotosensitizers for theranostic photodynamic therapy. Chinese Chemical Letters, 2021, 32, 3903-3906.

33.    Tang, Shanliang; An, Jing; Song, Fengling;* Lv, Meiheng; Han, Keli; Peng, Xiaojun. Extending the legible time of light-responsive rewritable paper with a tunable photochromic diarylethene molecule. ACS Applied Materials & Interfaces 2021, 13, 51441-51425.

34.    Chen, Miaomiao; Song, Jitao;* Zhu, Jialong; Hong, Gaobo; An, Jing; Feng, Erting; Peng, Xiaojun; Song, Fengling.* A Dual-Nanozyme-Catalyzed Cascade Reactor for Enhanced Photodynamic Oncotherapy against Tumor Hypoxia. Adv. Healthcare Mater., 2021, 10, 2101049.

35.    Shao, Yutong; Song, Jitao;* Li, Xiaorong; Ren, Guoqing; Song, Fengling;* Synthesis of Noble Metal M@YSiO 2 Yolk−Shell Nanoparticles with Thin Organic/Inorganic Hybrid Outer Shells via an Aqueous Medium Phase. Langmuir 2021, 37, 7237-7245.

36.    Liu, Yuhan; Chen, Miaomiao; Zhao,Yanliang; Lv, Shibo; Zheng, Daoyuan; Dapeng, Liu;* Song, Fengling;* A Novel D-A-D Photosensitizer for Efficient NIR Imaging and Photodynamic Therapy. ChemBioChem 2021, 22, 2161-2167.

37.    Lv, Fangyuan; Liu, Dapeng;* Zheng, Wen-heng; Zhao,Yanliang; Song, Fengling;* BOPHY-Based Aggregation-Induced-Emission Nanoparticle Photosensitizers for Photodynamic Therapy. ACS Appl. Nano Mater. 2021, 4, 6012-6019.

38.    Li, Xiaorong; Shao, Yutong; Lv, Shibo; Tian, Jiarui; Zheng, Daoyuan; Song, Jitao;* Song, Fengling;* Au@mSiO 2 core–shell nanoparticles loaded with fluorescent dyes: synthesis and application for imaging performance. Dalton Trans., 2021, 50, 5624-5631.

39.    Miao, Yuyang; Lv, Shibo; Zheng, Daoyuan; Liu, Yuhan; Liu, Dapeng;* Song, Fengling;* Porphyrin-based metal coordination polymers with self-assembly pathway-dependent properties for photodynamic and photothermal therapy. Biomater. Sci., 2021, 9, 2533-2541.

40.    Chen, Miaomiao; Liu, Dapeng; Liu, Fusheng; Wu,Yingnan; Peng, Xiaojun; Song, Fengling.* Recent advances of redox-responsive nanoplatforms for tumor theranostics. Journal of Controlled Release, 2021, 332,269-284.

41.    Jin, Lin; Lv, Shibo; Miao, Yuyang; Liu,Dapeng*; Song, Fengling;* Recent Development of Porous Porphyrin-based Nanomaterials for Photocatalysis. ChemCatChem, 2021, 13, 140—152.

42.    Lv, Shibo; Miao, Yuyang; Zheng, Daoyang; Li, Xiaoju; Liu,Dapeng*; Song, Fengling;* Self-Assembled Platinum Supramolecular Metallacycles Based on a Novel TADF Photosensitizer for Efficient Cancer Photochemotherapy. Mol. Pharmaceutics, 2021, 18, 1229−1237

43.    Liu, Yuhan; Lv, Shibo; Liu, Dapeng;* Song, Fengling;* Recent development of amorphous metal coordination polymers for cancer therapy. Acta Biomaterialia, 2020, 116, 16-31.

44.    Lv, Shibo; Miao, Yuyang; Liu,Dapeng*; Song, Fengling.* Recent Development of Photothermal Agents (PTAs) Based on Small Organic Molecular Dyes. ChemBioChem, 2020, 21, 2098—2110.

45.    Ying, Huiyi; Wu,Yingnan; Peng, Xiaojun; Song, Fengling.* A turn-on TADF chemosensor for sulfite with a microsecond-scale luminescence lifetime. Chemical Communications, 2020, 56, 10549—10551.

46.    Wu,Yingnan; Zhao, Yanliang; Zhou, Panwang; Zheng, Daoyuan; Wang, Honglei; Tang, Shanliang; Tian, Jiarui; Yang, Songqiu; Deng, Weiqiao; Han, Keli; Song, Fengling.* Enhancing Intersystem Crossing to Achieve Thermally Activated Delayed Fluorescence in a Water-Soluble Fluorescein Derivative with a Flexible Propenyl Group. J. Phys. Chem. Lett. 2020, 11, 5692–5698.

47.    Jiao, Long; Liu, Yongzhuo; Zhang, Xiaoye; Hong, Gaobo; Zheng, Jing; Cui, Jingnan; Peng, Xiaojun Song, Fengling.* Constructing a Local Hydrophobic Cage in Dye-Doped Fluorescent Silica Nanoparticles to Enhance the Photophysical Properties. ACS Central Science 2020, 6,747-759.

48.    Zheng, Jing; Liu, Yongzhuo; Song, Fengling;* Jiao, Long; Wu,Yingnan; Peng, Xiaojun. A nitroreductase-activatable near-infrared theranostic photosensitizer for photodynamic therapy under mild hypoxia. Chemical Communications, 2020, 56, 5819-5822.

49.    Wu,Yingnan; Jiao, Long; Song, Fengling;* Chen, Miaomiao; Liu, Dapeng;* Yang, Wei; Yuming, Sun; Hong, Gaobo; Wu,Yingnan; Liu, lingge; Peng, Xiaojun. Achieving Long-lived thermally activated delayed fluorescence in the atmospheric aqueous environment by nano-encapsulation. Chemical Communications, 2019, 55, 14522--14525

50.    Chen, Wenlong; Song, Fengling.* Thermally activated delayed fluorescence molecules and their new applications aside from OLEDs. Chinese Chemical Letters, 2019, 30, 1717-1730.

51.    Liu, Zhiwei; Shi, Wenbo; Hong, Gaobo; Chen,Wenlong; Song, Bo; Peng, Xiaojun; Xiong, Xiaoqing;* Song, Fengling.* A dual-targeted theranostic photosensitizer based on a TADF fluorescein derivative. Journal of Controlled Release 2019, 310, 1−10.

52.    Jiao, Long; Zhang, Xiaoye; Cui, Jingnan; Peng, Xiaojun Song, Fengling.* Three-in-one Functional Silica Nanocarrier with Singlet Oxygen Generation, Storage/release and Self-monitoring for Enhanced Fractional Photodynamic Therapy. ACS Applied Materials & Interfaces 2019, 11, 27250-27257.

53.    Liu, Zhiwei; Song, Fengling;* Shi, Wenbo; Gurzadyan, Gagik; Yin, Huiyi; Song, Bo; Liang, Ri; Peng, Xiaojun. Nitroreductase-activatable theranostic molecules with high PDT efficiency under mild hypoxia based on a TADF fluorescein derivative. ACS Applied Materials & Interfaces 2019, 11, 15426−15435.

54.    Chen, Wenlong; Song, Fengling;* Tang, Shanliang; Hong, Gaobo; Wu,Yingnan; Peng, Xiaojun. Red-to-blue photon up-conversion with high efficiency based on a TADF fluorescein derivative. Chemical Communications, 2019, 55, 4375 - 4378

55.    Tang, Shanliang; Song, Fengling;* Lu, Meiheng; Han, Keli; Peng, Xiaojun. Rational design of a visible-light photochromic diarylethene: a simple strategy by extending conjugation with electron donating groups. SCIENCE CHINA Chemistry 2019, 62, 451-459.

56.    Jiao, Long; Song, Fengling;* Cui, Jingnan; Peng, Xiaojun. A near infrared heptamethine aminocyanine dye with a long-living excited triplet state for photodynamic therapy. Chemical Communications, 2018, 54, 9198 – 9201.

57.    Liu, Zhiwei; Song, Fengling;* Song, Bo; Jiao, Long; An, Jing; Yuan, Jingli; Peng, Xiaojun. A FRET chemosensor for hypochlorite with large Stokes Shifts and long-lifetime emissions. Sensors & Actuators: B. Chemical 2018, 262958-965.

58.    An, Jing; Wu, Yingnan; Lu, Meiheng; Han, Keli; Song, Fengling;* Peng, Xiaojun. Long-Wavelength Chromophores with Thermally Activated Delayed Fluorescence Based on Fluorescein Derivatives. Journal of Photonics for Energy, 2018, 8(3), 032103.

59.    Song, Fengling;* Liang, Ri; Deng, Jundie; Liu, Zhiwei, Peng, Xiaojun. Fine-tailoring the linker of near-infrared fluorescence probes for nitroreductase imaging in hypoxic tumour cells. Chinese Chemical Letters, 2017, 28, 1997-2000.

60.    Jiao, Long; Song, Fengling;* Zhang, Biyou; Ning, Houfu; Cui, Jingnan;* Peng, Xiaojun. Improving brightness and photostability of NIR fluorescent silica nanoparticles through rational fine-tuning of the covalent encapsulation methods. Journal of Materials Chemistry B, 2017, 5, 5278 - 5283

61.    Wu, Yingnan; Song, Fengling;* Luo, Wenfang; Liu, Zhiwei; Song, Bo; Peng, Xiaojun. Enhanced Thermally Activated Delayed Fluorescence in New Fluorescein Derivatives By Introducing Aromatic Carbonyl Groups. ChemPhotoChem 2017, 1, 79-83.

62.    Wang, Xu; Song, Fengling;* Peng, Xiaojun. A versatile fluorescent probe for imaging viscosity and hypochlorite in living cells. Dyes & Pigments. 2016, 125, 89-94

63.    Xiong, Xiaoqing; Zheng, Laijiu;* Yan, Jun; Ye, Fang; Qian, Yongfang; Song, Fengling.*A turn-on and colorimetric metal-free long lifetime fluorescent probe and its application for time-resolved luminescent detection and bioimaging of cysteine. RSC Adv., 2015, 5, 53660-53664.

64.    Xiong, Xiaoqing; Song, Fengling;* Wang, Jingyun; Zhang, Yukang; Xue, Yingying; Sun, Liangliang; Jiang, Na; Gao, Pan; Tian, Lu; Peng, Xiaojun. Thermally Activated Delayed Fluorescence of Fluorescein Derivative for Time-Resolved and Confocal Fluorescence Imaging. J. Am. Chem. Soc. 2014, 136, 95909597

65.    Song, Fengling;* Ning, Houfu; She, Haiying; Wang, Jingyun; Peng, Xiaojun. A turn-on fluorescent probe for Au3+ based on rodamine derivative and its bioimaging application. Science China Chemistry. 2014, 57, 10431047

66.    Song, Fengling;* Xue,Yingying; Wang, Xu; Wang, Jingyun; Xiong, Xiaoqing; Peng, Xiaojun. Ratiometric fluorescent probe based on novel red-emission BODIPY for determination of bovine serum albumin. Chemical Research in Chinese Universities. 2014, 30, 738742.

67.    Chen, Bo; Song, Fengling;* Sun, Shiguo; Fan, Jiangli; Peng, Xiaojun. A Highly Sensitive Fluorescent Chemosensor for Ruthenium: Oxidation Plays Triple Roles. Chem. A Eur. J., 2013, 19,10115-10118.

68.    She, Haiying; Song, Fengling;* Xu, Juan; Xiong, Xiaoqing; Chen,Gengwen; Fan, Jiangli; Sun, Shiguo; Peng, Xiaojun.* A New Tridentate Sulfur Receptor as A Highly Selective and Sensitive Fluorescent Sensor for Cu2+ ions. Chem. An Asian J., 2013, 8,2762-2767.

69.    Wang, Junyu; Song, Fengling;* Wang, Jingyun; Peng, Xiaojun.* A Near-infrared and Ratiometric Fluorescent Chemosensor for Palladium. Analyst, 2013, 138, 3667-3672.

70.    Chen,Gengwen; Song, Fengling;* Xiong, Xiaoqing; Peng, Xiaojun.* Fluorescent Nanosensors Based on Fluorescence Resonance Energy Transfer (FRET). Ind. Eng. Chem. Res., 2013, 52, 11228-112245..

71.    Xiong, Xiaoqing; Song, Fengling;* Chen, Gengwen; Sun, Wen; Wang, Jingyun; Gao, Pan; Zhang, Yukang; Qiao,Bo; Li, Wenfang; Sun, Shiguo; Fan, Jiangli; Peng, Xiaojun.* Construction of Long-Wavelength Fluorescein Analogues and Their Application as Fluorescent Probes. Chem. A Eur. J., 2013,19, 6538-6545.

72.    Xiong, Xiaoqing; Song, Fengling;* Sun, Shiguo; Fan, Jiangli; Qiang, Xinxin; Wang, Xu; Dou, Bairui; Peng, Xiaojun.* Red-Emissive Fluorescein Derivatives and Detection of Bovine Serum Albumin. Asian J. Org. Chem., 2013, 2, 145 – 149.

73.    Chen,Gengwen; Song, Fengling;* Wang, Jingyun; Yang, Zhigang; Sun,Shiguo; Fan, Jiangli; Qiang, Xinxin; Wang, Xu; Dou, Bairui; Peng, Xiaojun.* FRET spectral unmixing: a ratiometric fluorescent nanoprobe for hypochlorite. Chem.Commun., 2012, 48 (24), 2949 – 2951.

74.    Chen,Gengwen; Song, Fengling;* Wang, Xu; Fan, Jiangli; Sun,Shiguo; Qiang, Xinxin; Dou, Bairui; Peng, Xiaojun.* Bright and Stable Cy3-Encapsulated Fluorescent Silica Nanoparticles with a Large Stokes Shift. Dyes & Pigments. 2012,93,1532-1537

75.    Koide, Kazunori;* Osman, Sami; Garner, Amanda L; Song, Fengling; Dixon, Tracy; Greenberger, Joel S; Epperly, Michael W. The Use of 3,5,40-Tri-O-acetylresveratrol as a Potential Prodrug for Resveratrol Protects Mice from γ-Irradiation-Induced Death. ACS Med. Chem. Lett. 2011, 2, 270–274

76.    Peng, Xiaojun;* Yang, Zhigang; Wang, Jingyun; Fan, Jiangli; He, Yanxia; Song, Fengling; Wang, Bingshuai; Sun, Shiguo; Qu, Junle; Qi, Jing; Yan, Meng. Fluorescence Ratiometry and Fluorescence Lifetime Imaging: Using a Single Molecular Sensor for Dual Mode Imaging of Cellular Viscosity. J. Am. Chem. Soc.. 2011, 133, 6626–6635

77.    Peng, Xiaojun;* Wu, Tong; Fan, Jiangli; Wang, Jingyun; Zhang, Si; Song, Fengling; Sun, Shiguo. An Effective Minor Groove Binder as a Red Fluorescent Marker for Live-Cell DNA Imaging and Quantification. Angew. Chem. Int. Ed. 2011, 50, 4180 4183

78.    Song, Fengling; Carder, Evan J.; Kohler, Clare C.; Koide, Kazunori.* Studies Toward an Ideal Fluorescence Method to Measure Palladium in Functionalized Organic Molecules: Effects of Sodium Borohydride, Temperature, Phosphine Ligand, and Phosphate Ions on Kinetics. Chem.-Eur. J., 2010, 16,13500-13508.

79.    Li, Honglin; Fan, Jiangli; Song, Fengling; Zhu, Hao; Du, Jianjun; Sun, Shiguo; Peng, Xiaojun.* Fluorescent Probes for Pd2+ Detection by AllylideneHydrazone Ligands with Excellent Selectivity and Large Fluorescence Enhancement. Chem.-Eur. J., 2010, 16,12349-12356.

80.    Song, Fengling; Wang, Li; Qiao, Xiaoqiang; Wang, Bingshuai; Sun, Shiguo; Fan, Jiangli; Zhang, Lihua; Peng, Xiaojun.* Asymmetric trimethine 3H-indocyanine dyes: efficient synthesis and protein Labeling. Org. Biomol. Chem., 2010, 8, 4249–4251

81.    Garner, Amanda L; Song, Fengling; Koide, Kazunori.* Enhancement of a Catalysis-Based Fluorometric Detection method for palladium through rational fine-tuning of the palladium species.  J. Am. Chem. Soc. 2009, 131, 5163-5171.

82.    Song, Fengling; Watanabe, Shuji; Floreancig, Paul E.; Koide, Kazunori.* Oxidation-resistant fluorogenic probe for mercury based on alkyne oxymercuration.  J. Am. Chem. Soc. 2008, 130, 16460–16461.

83.    Koide, Kazunori;* Song, Fengling; de Groh, Eric D.; Garner, Amanda L.; Mitchell, Valerie D.; Davidson, Lance A.; Hukriede, Neil A. Scalable and concise synthesis of dichlorofluorescein derivatives displaying tissue permeation in live zebrafish embryos. ChemBioChem 2008, 9, 214128.

84.    Song, Fengling; Garner, Amanda L; Koide, Kazunori.* A highly sensitive fluorescent sensor for palladium based on the allylic oxidative insertion mechanism.  J. Am. Chem. Soc. 2007, 129, 12354–12355. (Featured in C&E News 2007, October 1 issue, pg. 30.)

85.    Wang, Yanan; Guo, Xinwen;* Zhang, Chen; Song, Fengling; Wang, Xiangsheng; Liu, Hai-ou; Xu, Xiaochun; Song, Chunshan; Zhang, Weiping; Liu, Xiumei; Han, Xiuwen; Bao, Xinhe.   Influence of calcination temperature on the stability of fluorinated nanosized HZSM-5 in the methylation of biphenyl. Catal. Lett. 2006, 107, 209-214.

86.    Peng, Xiaojun;* Song, Fengling; Lu, Erhu; Wang, Yanan; Zhou, Wei; Fan, Jiangli; Gao, Yunling. Heptamethine cyanine dyes with a large stokes shift and strong fluorescence: A paradigm for excited-state intramolecular charge transfer. J. Am. Chem. Soc. 2005, 127, 4170-4171.

87.    Song, Fengling; Peng, Xiaojun;* Lu, Erhu; Wang, Yanan; Zhou, Wei; Fan, Jiangli. Tuning the photoinduced electron transfer in near-infrared heptamethine cyanine dyes. Tetrahedron Lett. 2005, 46, 4817-4820.

88.    Lu, Erhu; Peng, Xiaojun;* Song, Fengling; Fan, Jiangli. A novel fluorescent sensor for triplex DNA. Bioorg. Med. Chem. Lett. 2005, 15(2), 255-257.

89.    Song, Fengling; Peng, Xiaojun;* Lu, Erhu; Zhang, Rong; Chen, Xiuying; Song, Bo. Syntheses, spectral properties and photostabilities of novel water-soluble near-infrared cyanine dyes. J. of Photochem. & Photobio. A: Chem. 2004, 168, 53–57.

90Wang, Liqiu; Peng, Xiaojun;* Song, Fengling; Lu, Erhu; Cui, Jingnan; Gao, Xinqin; Lu, Rongwen. New near-infrared indocyanines and their spectral properties in SiO2 sol-gel. Dyes and Pigments. 2004, 61(2), 103-107.


Education
  • 1999-9 — 2005-10
    大连理工大学
    应用化学
    Doctoral Degree in Engineering
  • 1995-9 — 1999-7
    大连理工大学
    应用化学
    Bachelor's Degree in Science
Publication
Research direction

No contents

Papers

1. 孙涵. Boosting Type-I and Type-II ROS Production of Water-Soluble Porphyrin for Efficient Hypoxic Tumor Therapy .Molecular Pharmaceutics .2023,20 (1):606

2. . Antimicrobial protection of two controlled release silver nanoparticles on simulated silk cultural relic .Journal of Colloid and Interface Science 2012.2023,652 :901

3. . Stable Hybrid Nanocapsules with Gold Nanorods and Cyanine Dyes for Near-Infrared Photothermal Ablation of Subcutaneous Tumor .ADVANCED THERAPEUTICS.2023

4. Shao, Yutong. Integration of Activation by Hypoxia and Inhibition Resistance of Tumor cells to Apoptosis for Precise and Augmented Photodynamic Therapy .Advanced Healthcare Materials.2023

5. . A "Chase and Block" Strategy for Enhanced Cancer Therapy with Hypoxia-Promoted Photodynamic Therapy and Autophagy Inhibition Based on Upconversion Nanocomposites .Advanced Healthcare Materials.2023

6. 孙涵. Boosting Type-I and Type-II ROS Production of Water-Soluble Porphyrin for Efficient Hypoxic Tumor Therapy. .Molecular Pharmaceutics.2022,20 (1):606-615

7. . Antimicrobial protection of two controlled release silver nanoparticles on simulated silk cultural relic .Journal of Colloid and interface science.2023 (652)

8. 方旭. Poly(ionic liquid)s for Photo-Driven CO2 Cycloaddition: Electron Donor-Acceptor Segments Matter .ADVANCED SCIENCE.2023,10 (8)

9. Feng, Erting. Anti-photobleaching cyanine-based nanoparticles with simultaneous PET and ACQ effects for improved tumor photothermal therapy .Chemical Engineering Journal.2022,432

10. . Poly(ionic liquid)s for Photo-Driven CO2 Cycloaddition: Electron Donor-Acceptor Segments Matter .ADVANCED SCIENCE.2023,10 (8)

11. An, Jing. An unexpected strategy to alleviate hypoxia limitation of photodynamic therapy by biotinylation of photosensitizers .NATURE COMMUNICATIONS.2022,13 (1):2225

12. 吕世博. Rational design of a small organic photosensitizer for NIR-I imaging-guided synergistic photodynamic and photothermal therapy .BIOMATERIALS SCIENCE .2022,10 (17):4785

13. 吕方圆. Photothermal agents based on small organic fluorophores with intramolecular motion. .2022

14. 吕世博. Rational design of a small organic photosensitizer for NIR-I imaging-guided synergistic photodynamic and photothermal therapy .2022

15. 赵沿亮. The Second Excited Triplet-State Facilitates TADF and Triplet-Triplet Annihilation Photon Upconversion via a Thermally Activated Reverse Internal Conversion .Advanced Optical Materials.2022,10 (6)

16. 吕方圆. BOPHY-Based Aggregation-Induced-Emission Nanoparticle Photosensitizers for Photodynamic Therapy .ACS Applied Nano Materials.2021,4 (6):6012

17. 邵宇童. Synthesis of Noble Metal M@YSiO2 Yolk-Shell Nanoparticles with Thin Organic/Inorganic Hybrid Outer Shells via an Aqueous Medium Phase .LANGMUIR.2021,37 (23):7237

18. 李晓蓉. Au@mSiO(2) core-shell nanoparticles loaded with fluorescent dyes: synthesis and application for imaging performance .DaltonTrans.2021

19. Chen, Miaomiao. A Dual-Nanozyme-Catalyzed Cascade Reactor for Enhanced Photodynamic Oncotherapy against Tumor Hypoxia .Advanced Healthcare Materials.2021

20. 靳琳. Recent Development of Porous Porphyrin-based Nanomaterials for Photocatalysis .ChemCatChem.2021,13 (1):140

21. 刘雨涵. Recent development of amorphous metal coordination polymers for cancer therapy .Acta Biomaterialia.2020,116 :16

22. 吴蓥男. Enhancing Intersystem Crossing to Achieve Thermally Activated Delayed Fluorescence in a Water-Soluble Fluorescein Derivative with a Flexible Propenyl Group .Journal of Physical Chemistry Letters.2020,11 (14):5692

23. 吕世博. Recent Development of Photothermal Agents (PTAs) Based on Small Organic Molecular Dyes .Chembiochem.2020,21 (15):2098

24. 刘雨涵. A Novel D-A-D Photosensitizer for Efficient NIR Imaging and Photodynamic Therapy .Chembiochem.2021

25. 李晓蓉. Au@mSiO(2) core-shell nanoparticles loaded with fluorescent dyes: synthesis and application for imaging performance .DaltonTrans.2021

26. 苗钰阳. Porphyrin-based metal coordination polymers with self-assembly pathway-dependent properties for photodynamic and photothermal therapy .BIOMATERIALS SCIENCE .2021,9 (7):2533

27. 吕世博. Self-Assembled Platinum Supramolecular Metallacycles Based on a Novel TADF Photosensitizer for Efficient Cancer Photochemotherapy .Molecular Pharmaceutics .2021,18 (3):1229

28. 吴蓥男. Achieving long-lived thermally activated delayed fluorescence in the atmospheric aqueous environment by nano-encapsulation .chemical communications.2019,55 (96):14522

29. Dapeng Liu , Song Fengling  and 吴蓥男. Achieving Long-lived thermally activated delayed fluorescence in the atmospheric aqueous environment by nanoencapsulation .CHEMICAL COMMUNICATIONS Journal.2019

30. Dapeng Liu , Song Fengling  and 吴蓥男. Achieving Long-lived thermally activated delayed fluorescence in the atmospheric aqueous environment by nanoencapsulation .CHEMICAL COMMUNICATIONS Journal.2019

31. Song Fengling  and Chen, Wenlong. Red- to- blue photon up- conversion with high efficiency based on a TADF fluorescein derivative .chemical communications.2019,55 (30):4375

32. Song Fengling  and Liu, Zhiwei. Nitroreductase-Activatable Theranostic Molecules with High PDT Efficiency under Mild Hypoxia Based on a TADF Fluorescein Derivative .ACS Applied Materials & Interfaces.2019,11 (17):15426

Patens
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