宋锋玲

个人信息Personal Information

教授 博士生导师 硕士生导师

性别:男

毕业院校:大连理工大学

学历:研究生(博士后)

学位:工学博士学位

在职信息:在职

所在单位:前沿交叉科学青岛研究院

入职时间:2019-02-01

联系方式:songfl@sdu.edu.cn


电子邮箱:songfl@sdu.edu.cn

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个人简介Personal Profile

宋锋玲, 山东大学前沿交叉科学青岛研究院教授,博士生导师,山东大学杰出青年学者。首批国家自然科学基金优秀青年项目获得者,教育部新世纪优秀人才计划入选者,大连市杰出青年科技人才培育计划入选者。主要从事有机荧光染料的结构性能研究,并开展荧光染料及功能化荧光纳米粒子在生物医学领域的成像与光学治疗研究。研究成果获2007年全国百篇优秀博士学位论文提名奖; 2012年教育部自然科学一等奖;2012年辽宁省自然科学一等奖;2016年辽宁省自然科学学术成果论文类一等奖,2018年中国石油和化学工业联合会创新团队奖。

学习工作经历:
1995年09月至1999年07月大连理工大学应用化学专业,学士学位
1999年09月至2005年10月大连理工大学应用化学专业,博士学位
2006年01月至2006年11月美国Wayne State University化学系, 有机化学博士后
2006年12月至2009年11月美国University of Pittsburgh化学系, 有机化学博士后
2012年07月至2012年11月美国Washington University in St Louis医学院, 访问学者
2009年12月至2012年12月大连理工大学精细化工国家重点实验室副教授。
2012年12月至2019年大连理工大学精细化工国家重点实验室教授
2019年至今 山东大学前沿交叉科学青岛研究院教授


代表性论文:

1.  Jiao, Long; Liu, Yongzhuo; Zhang, Xiaoye; Hong, Gaobo; Zheng, Jing; Cui, Jingnan; Peng, Xiaojun Song, Fengling.* Constructing a Local Hydrophobic Cage in Dye-Doped Fluorescent Silica Nanoparticles to Enhance the Photophysical Properties. ACS Central Science 20206,747-759. 

2. Xiong, Xiaoqing; Song, Fengling;* Wang, Jingyun; Zhang, Yukang; Xue, Yingying; Sun, Liangliang; Jiang, Na; Gao, Pan; Tian, Lu; Peng, Xiaojun. Thermally Activated Delayed Fluorescence of Fluorescein Derivative for Time-Resolved and Confocal Fluorescence Imaging. J. Am. Chem. Soc. 2014, 136, 9590−9597. 

3. Song, Fengling; Watanabe, Shuji; Floreancig, Paul E.; Koide, Kazunori.* Oxidation-resistant fluorogenic probe for mercury based on alkyne oxymercuration. J. Am. Chem. Soc. 2008, 130, 16460–16461. 

4. Song, Fengling; Garner, Amanda L; Koide, Kazunori.* A highly sensitive fluorescent sensor for palladium based on the allylic oxidative insertion mechanism. J. Am. Chem. Soc. 2007, 129, 12354–12355. (Featured in C&E News 2007, October 1 issue, pg. 30.)

5. Peng, Xiaojun;* Song, Fengling; Lu, Erhu; Wang, Yanan; Zhou, Wei; Fan, Jiangli; Gao, Yunling. Heptamethine cyanine dyes with a large stokes shift and strong fluorescence: A paradigm for excited-state intramolecular charge transfer. J. Am. Chem. Soc. 2005, 127, 4170-4171.


逐年论文列表:

1.       Chen, Miaomiao; Liu, Dapeng; Liu, Fusheng; Wu,Yingnan; Peng, Xiaojun; Song, Fengling;* Recent advances of redox-responsive nanoplatforms for tumor theranostics. Journal of Controlled Release, 2021, 332,269-284.

2.       Jin, Lin; Lv, Shibo; Miao, Yuyang; Liu,Dapeng*; Song, Fengling;* Recent Development of Porous Porphyrin-based Nanomaterials for Photocatalysis. ChemCatChem, 2021, 13, 140—152.

3.       Lv, Shibo; Miao, Yuyang; Zheng, Daoyang; Li, Xiaoju; Liu,Dapeng*; Song, Fengling;* Self-Assembled Platinum Supramolecular Metallacycles Based on a Novel TADF Photosensitizer for Efficient Cancer Photochemotherapy. Mol. Pharmaceutics, 2021, 18, 1229−1237

4.       Liu, Yuhan; Lv, Shibo; Liu,Dapeng; Song, Fengling;* Recent development of amorphous metal coordination polymers for cancer therapy. Acta Biomaterialia, 2020, 116, 16-31.

5.       Lv, Shibo; Miao, Yuyang; Liu,Dapeng*; Song, Fengling;* Recent Development of Photothermal Agents (PTAs) Based on Small Organic Molecular Dyes. ChemBioChem, 2020, 21, 2098—2110.

6.       Ying, Huiyi; Wu,Yingnan; Peng, Xiaojun; Song, Fengling;* A turn-on TADF chemosensor for sulfite with a microsecond-scale luminescence lifetime. Chemical Communications, 2020, 56, 10549—10551.

7.       Wu,Yingnan; Zhao, Yanliang; Zhou, Panwang; Zheng, Daoyuan; Wang, Honglei; Tang, Shanliang; Tian, Jiarui; Yang, Songqiu; Deng, Weiqiao; Han, Keli; Song, Fengling.* Enhancing Intersystem Crossing to Achieve Thermally Activated Delayed Fluorescence in a Water-Soluble Fluorescein Derivative with a Flexible Propenyl Group. J. Phys. Chem. Lett. 202011, 5692–5698.

8.       Jiao, Long; Liu, Yongzhuo; Zhang, Xiaoye; Hong, Gaobo; Zheng, Jing; Cui, Jingnan; Peng, Xiaojun Song, Fengling.* Constructing a Local Hydrophobic Cage in Dye-Doped Fluorescent Silica Nanoparticles to Enhance the Photophysical Properties. ACS Central Science 2020, 6,747-759.

9.       Zheng, Jing; Liu, Yongzhuo; Song, Fengling;* Jiao, Long; Wu,Yingnan; Peng, Xiaojun. A nitroreductase-activatable near-infrared theranostic photosensitizer for photodynamic therapy under mild hypoxia. Chemical Communications, 2020, 56, 5819-5822.

10.    Wu,Yingnan; Jiao, Long; Song, Fengling;* Chen, Miaomiao; Liu, Dapeng;* Yang, Wei; Yuming, Sun; Hong, Gaobo; Wu,Yingnan; Liu, lingge; Peng, Xiaojun. Achieving Long-lived thermally activated delayed fluorescence in the atmospheric aqueous environment by nano-encapsulation. Chemical Communications, 2019, 55, 14522--14525

11.    Chen, Wenlong; Song, Fengling.* Thermally activated delayed fluorescence molecules and their new applications aside from OLEDs. Chinese Chemical Letters201930, 1717-1730.

12.    Liu, Zhiwei; Shi, Wenbo; Hong, Gaobo; Chen,Wenlong; Song, Bo; Peng, Xiaojun; Xiong, Xiaoqing;* Song, Fengling.* A dual-targeted theranostic photosensitizer based on a TADF fluorescein derivative. Journal of Controlled Release 2019, 310, 1−10.

13.    Jiao, Long; Zhang, Xiaoye; Cui, Jingnan; Peng, Xiaojun Song, Fengling.* Three-in-one Functional Silica Nanocarrier with Singlet Oxygen Generating, Storage/release and Self-monitoring for Enhanced Fractional Photodynamic Therapy. ACS Applied Materials & Interfaces 2019, 11, 27250-27257.

14.    Liu, Zhiwei; Song, Fengling;* Shi, Wenbo; Gurzadyan, Gagik; Yin, Huiyi; Song, Bo; Liang, Ri; Peng, Xiaojun. Nitroreductase-activatable theranostic molecules with high PDT efficiency under mild hypoxia based on a TADF fluorescein derivative. ACS Applied Materials & Interfaces 2019, 11, 15426−15435.

15.    Chen, Wenlong; Song, Fengling;* Tang, Shanliang; Hong, Gaobo; Wu,Yingnan; Peng, Xiaojun. Red-to-blue photon up-conversion with high efficiency based on a TADF fluorescein derivative. Chemical Communications, 2019, 55, 4375 - 4378

16.    Tang, Shanliang; Song, Fengling;* Lu, Meiheng; Han, Keli; Peng, Xiaojun. Rational design of a visible-light photochromic diarylethene: a simple strategy by extending conjugation with electron donating groups. SCIENCE CHINA Chemistry 2019, 62, 451-459.

17.    Jiao, Long; Song, Fengling;* Cui, Jingnan; Peng, Xiaojun. A near infrared heptamethine aminocyanine dye with a long-living excited triplet state for photodynamic therapy. Chemical Communications, 2018, 54, 9198 – 9201.

18.    Liu, Zhiwei; Song, Fengling;* Song, Bo; Jiao, Long; An, Jing; Yuan, Jingli; Peng, Xiaojun. A FRET chemosensor for hypochlorite with large Stokes Shifts and long-lifetime emissions. Sensors & Actuators: B. Chemical 2018, 262958-965.

19.    An, Jing; Wu, Yingnan; Lu, Meiheng; Han, Keli; Song, Fengling;* Peng, Xiaojun. Long-Wavelength Chromophores with Thermally Activated Delayed Fluorescence Based on Fluorescein Derivatives. Journal of Photonics for Energy20188(3), 032103.

20.    Song, Fengling;* Liang, Ri; Deng, Jundie; Liu, Zhiwei, Peng, Xiaojun. Fine-tailoring the linker of near-infrared fluorescence probes for nitroreductase imaging in hypoxic tumour cells. Chinese Chemical Letters201728, 1997-2000.

21.    Jiao, Long; Song, Fengling;* Zhang, Biyou; Ning, Houfu; Cui, Jingnan;* Peng, Xiaojun. Improving brightness and photostability of NIR fluorescent silica nanoparticles through rational fine-tuning of the covalent encapsulation methods. Journal of Materials Chemistry B2017, 5, 5278 - 5283

22.    Wu, Yingnan; Song, Fengling;* Luo, Wenfang; Liu, Zhiwei; Song, Bo; Peng, Xiaojun. Enhanced Thermally Activated Delayed Fluorescence in New Fluorescein Derivatives By Introducing Aromatic Carbonyl Groups. ChemPhotoChem 20171, 79-83.

23.    Wang, Xu; Song, Fengling;* Peng, Xiaojun. A versatile fluorescent probe for imaging viscosity and hypochlorite in living cells. Dyes & Pigments. 2016125, 89-94

24.    Xiong, Xiaoqing; Zheng, Laijiu;* Yan, Jun; Ye, Fang; Qian, Yongfang; Song, Fengling.*A turn-on and colorimetric metal-free long lifetime fluorescent probe and its application for time-resolved luminescent detection and bioimaging of cysteine. RSC Adv.20155, 53660-53664.

25.    Xiong, Xiaoqing; Song, Fengling;* Wang, Jingyun; Zhang, Yukang; Xue, Yingying; Sun, Liangliang; Jiang, Na; Gao, Pan; Tian, Lu; Peng, Xiaojun. Thermally Activated Delayed Fluorescence of Fluorescein Derivative for Time-Resolved and Confocal Fluorescence Imaging. J. Am. Chem. Soc. 2014136, 95909597

26.    Song, Fengling;* Ning, Houfu; She, Haiying; Wang, Jingyun; Peng, Xiaojun. A turn-on fluorescent probe for Au3+ based on rodamine derivative and its bioimaging application. Science China Chemistry. 201457, 10431047

27.    Song, Fengling;* Xue,Yingying; Wang, Xu; Wang, Jingyun; Xiong, Xiaoqing; Peng, Xiaojun. Ratiometric fluorescent probe based on novel red-emission BODIPY for determination of bovine serum albumin. Chemical Research in Chinese Universities. 201430, 738742.

28.    Chen, Bo; Song, Fengling;* Sun, Shiguo; Fan, Jiangli; Peng, Xiaojun. A Highly Sensitive Fluorescent Chemosensor for Ruthenium: Oxidation Plays Triple Roles. Chem. A Eur. J.201319,10115-10118.

29.    She, Haiying; Song, Fengling;* Xu, Juan; Xiong, Xiaoqing; Chen,Gengwen; Fan, Jiangli; Sun, Shiguo; Peng, Xiaojun.* A New Tridentate Sulfur Receptor as A Highly Selective and Sensitive Fluorescent Sensor for Cu2+ ions. Chem. An Asian J.20138,2762-2767.

30.    Wang, Junyu; Song, Fengling;* Wang, Jingyun; Peng, Xiaojun.* A Near-infrared and Ratiometric Fluorescent Chemosensor for Palladium. Analyst2013138, 3667-3672.

31.    Chen,Gengwen; Song, Fengling;* Xiong, Xiaoqing; Peng, Xiaojun.* Fluorescent Nanosensors Based on Fluorescence Resonance Energy Transfer (FRET). Ind. Eng. Chem. Res.201352, 11228-112245..

32.    Xiong, Xiaoqing; Song, Fengling;* Chen, Gengwen; Sun, Wen; Wang, Jingyun; Gao, Pan; Zhang, Yukang; Qiao,Bo; Li, Wenfang; Sun, Shiguo; Fan, Jiangli; Peng, Xiaojun.* Construction of Long-Wavelength Fluorescein Analogues and Their Application as Fluorescent Probes. Chem. A Eur. J.2013,19, 6538-6545.

33.    Xiong, Xiaoqing; Song, Fengling;* Sun, Shiguo; Fan, Jiangli; Qiang, Xinxin; Wang, Xu; Dou, Bairui; Peng, Xiaojun.* Red-Emissive Fluorescein Derivatives and Detection of Bovine Serum Albumin. Asian J. Org. Chem.20132, 145 – 149.

34.    Chen,Gengwen; Song, Fengling;* Wang, Jingyun; Yang, Zhigang; Sun,Shiguo; Fan, Jiangli; Qiang, Xinxin; Wang, Xu; Dou, Bairui; Peng, Xiaojun.* FRET spectral unmixing: a ratiometric fluorescent nanoprobe for hypochlorite. Chem.Commun.201248 (24), 2949 – 2951.

35.    Chen,Gengwen; Song, Fengling;* Wang, Xu; Fan, Jiangli; Sun,Shiguo; Qiang, Xinxin; Dou, Bairui; Peng, Xiaojun.* Bright and Stable Cy3-Encapsulated Fluorescent Silica Nanoparticles with a Large Stokes Shift. Dyes & Pigments. 2012,93,1532-1537

36.    Koide, Kazunori;* Osman, Sami; Garner, Amanda L; Song, Fengling; Dixon, Tracy; Greenberger, Joel S; Epperly, Michael W. The Use of 3,5,40-Tri-O-acetylresveratrol as a Potential Prodrug for Resveratrol Protects Mice from γ-Irradiation-Induced Death. ACS Med. Chem. Lett. 2011, 2, 270–274

37.    Peng, Xiaojun;* Yang, Zhigang; Wang, Jingyun; Fan, Jiangli; He, Yanxia; Song, Fengling; Wang, Bingshuai; Sun, Shiguo; Qu, Junle; Qi, Jing; Yan, Meng. Fluorescence Ratiometry and Fluorescence Lifetime Imaging: Using a Single Molecular Sensor for Dual Mode Imaging of Cellular Viscosity. J. Am. Chem. Soc.2011, 133, 6626–6635

38.    Peng, Xiaojun;* Wu, Tong; Fan, Jiangli; Wang, Jingyun; Zhang, Si; Song, Fengling; Sun, Shiguo. An Effective Minor Groove Binder as a Red Fluorescent Marker for Live-Cell DNA Imaging and Quantification. Angew. Chem. Int. Ed. 2011, 50, 4180 4183

39.    Song, Fengling; Carder, Evan J.; Kohler, Clare C.; Koide, Kazunori.* Studies Toward an Ideal Fluorescence Method to Measure Palladium in Functionalized Organic Molecules: Effects of Sodium Borohydride, Temperature, Phosphine Ligand, and Phosphate Ions on Kinetics. Chem.-Eur. J., 201016,13500-13508.

40.    Li, Honglin; Fan, Jiangli; Song, Fengling; Zhu, Hao; Du, Jianjun; Sun, Shiguo; Peng, Xiaojun.* Fluorescent Probes for Pd2+ Detection by AllylideneHydrazone Ligands with Excellent Selectivity and Large Fluorescence Enhancement. Chem.-Eur. J., 201016,12349-12356.

41.    Song, Fengling; Wang, Li; Qiao, Xiaoqiang; Wang, Bingshuai; Sun, Shiguo; Fan, Jiangli; Zhang, Lihua; Peng, Xiaojun.* Asymmetric trimethine 3H-indocyanine dyes: efficient synthesis and protein Labeling. Org. Biomol. Chem., 20108, 4249–4251

42.    Garner, Amanda L; Song, Fengling; Koide, Kazunori.* Enhancement of a Catalysis-Based Fluorometric Detection method for palladium through rational fine-tuning of the palladium species.  J. Am. Chem. Soc2009131, 5163-5171.

43.    Song, Fengling; Watanabe, Shuji; Floreancig, Paul E.; Koide, Kazunori.* Oxidation-resistant fluorogenic probe for mercury based on alkyne oxymercuration.  J. Am. Chem. Soc2008130, 16460–16461.

44.    Koide, Kazunori;* Song, Fengling; de Groh, Eric D.; Garner, Amanda L.; Mitchell, Valerie D.; Davidson, Lance A.; Hukriede, Neil A. Scalable and concise synthesis of dichlorofluorescein derivatives displaying tissue permeation in live zebrafish embryos. ChemBioChem 20089, 214128.

45.    Song, Fengling; Garner, Amanda L; Koide, Kazunori.* A highly sensitive fluorescent sensor for palladium based on the allylic oxidative insertion mechanism.  J. Am. Chem. Soc. 2007129, 12354–12355. (Featured in C&E News 2007, October 1 issue, pg. 30.)

46.    Wang, Yanan; Guo, Xinwen;* Zhang, Chen; Song, Fengling; Wang, Xiangsheng; Liu, Hai-ou; Xu, Xiaochun; Song, Chunshan; Zhang, Weiping; Liu, Xiumei; Han, Xiuwen; Bao, Xinhe.   Influence of calcination temperature on the stability of fluorinated nanosized HZSM-5 in the methylation of biphenyl. Catal. Lett. 2006107, 209-214.

47.    Peng, Xiaojun;* Song, Fengling; Lu, Erhu; Wang, Yanan; Zhou, Wei; Fan, Jiangli; Gao, Yunling. Heptamethine cyanine dyes with a large stokes shift and strong fluorescence: A paradigm for excited-state intramolecular charge transfer. J. Am. Chem. Soc. 2005127, 4170-4171.

48.    Song, Fengling; Peng, Xiaojun;* Lu, Erhu; Wang, Yanan; Zhou, Wei; Fan, Jiangli. Tuning the photoinduced electron transfer in near-infrared heptamethine cyanine dyes. Tetrahedron Lett200546, 4817-4820.

49.    Lu, Erhu; Peng, Xiaojun;* Song, Fengling; Fan, Jiangli. A novel fluorescent sensor for triplex DNA. Bioorg. Med. Chem. Lett2005, 15(2), 255-257.

50.    Song, Fengling; Peng, Xiaojun;* Lu, Erhu; Zhang, Rong; Chen, Xiuying; Song, Bo. Syntheses, spectral properties and photostabilities of novel water-soluble near-infrared cyanine dyes. J. of Photochem. & Photobio. A: Chem. 2004168, 53–57.

51.Wang, Liqiu; Peng, Xiaojun;* Song, Fengling; Lu, Erhu; Cui, Jingnan; Gao, Xinqin; Lu, Rongwen. New near-infrared indocyanines and their spectral properties in SiO2 sol-gel. Dyes and Pigments200461(2), 103-107.




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