论文成果
Mechanisms regulating oocyte meiotic resumption: roles of mitogen-activated protein kinase
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发表刊物：
Mol Endocrinol
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刊物所在地：
UK
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摘要：
Oocyte meiotic maturation is one of the important physiological requirements for species survival. However, little is known about the detailed events occurring during this process. A number of studies have demonstrated that MAPK plays a pivotal role in the regulation of meiotic cell cycle progression in oocytes, but controversial findings have been reported in both lower vertebrates and mammals. In this review, we summarized the roles of MAPK cascade and related signal pathways in oocyte meiotic reinitiation in both lower vertebrates and mammals. We also tried to reconcile the paradoxical results and highlight the new findings concerning the function of MAPK in both oocytes and the surrounding follicular somatic cells. The unresolved questions and future research directions regarding the role of MAPK in meiotic resumption are addressed.
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全部作者：
You-Qiang Su, Heng-Yu Fan, Heide Schatten
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第一作者：
Cheng-Guang Liang
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论文类型：
Minireview
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通讯作者：
Qing-Yuan Sun
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论文编号：
10.1210/me.2006-0408
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卷号：
21
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期号：
9
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页面范围：
2037-2055
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ISSN号：
0888-8809
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是否译文：
否
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发表时间：
2007-09-01
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