Yihe Wang, Associate Research Scientist and Master's Supervisor, is a recipient of the Young Scholars Future Program of Shandong University. Her current research focuses on interdisciplinary applications based on microfluidic technology, including tumor-on-a-chip models, pathogen detection, and the development and application of biomimetic polymer materials.

She has published over 30 papers, including more than 10 SCI-indexed articles as first or corresponding author in internationally renowned journals such as Advanced Science, Journal of Nanobiotechnology, and Advanced Healthcare Materials. She has presided over projects including the National Natural Science Foundation of China (Youth Program) and a sub-project of the Key R&D Program of Shandong Province. Additionally, she has participated as a key member in several major research initiatives, such as the General Program of the National Natural Science Foundation of China, the National Key R&D Program of China, and Key Technology R&D and Industrialization Demonstration Projects of Qingdao.

• University of Toronto
  Chemistry
• Zhejiang University
  Chemistry
• China University of Petroleum (East China)
  Applied Chemistry

• Department of Mechanical & Industrial EngineeringUniversity of Toronto
  Postdoctoral Fellow

1. Organ and organoid on a chip

2. Microfluidic systems for pathogenic microorganism detection

3. Biomimetic polymer materials

(1)Shuai Wang. Concurrent Detection of Amyloid-β Biomarkers via Dual-Channel Graphene Field-Effect Transistor with Liquid-Metal Van Der Waals Contacts for Alzheimer Screening .ACS Sensors .2025 ,10 (7):5067–5076

(2)Jun Li. Bipolar Ionic Diode with a Transformable Polyelectrolyte Network for High-Efficiency Ion Transport and Enhanced Sensitivity in Fluorescence-Based Heavy Metal Ion Detection .Analytical Chemistry .2025 ,97 (28):15018–15027

(3)Yihe Wang. In situ and dynamic screening of extracellular vesicles as predictive biomarkers in immune-checkpoint inhibitor therapies .Journal of Nanobiotechnology .2025 (23):411

(4)Yihe Wang,Mengqi Liu. A Microfluidic 3D-Tumor-Spheroid Model for the Evaluation of Targeted Therapies from Angiogenesis-Related Cytokines at the Single Spheroid Level .Advanced Healthcare Materials .2024 ,13 (31):2402321

(5)Yihe Wang. Recent methods of droplet microfluidics and their applications in spheroids and organoids .Lab on a Chip .2023 (23):1080

(6)Yihe Wang. Prediction of DNA Integrity from Morphological Parameters Using a Single‐Sperm DNA Fragmentation Index Assay .Advanced Science .2019 ,6 :1900712

(7)Yihe Wang. Two-dimensional arrays of cell-laden polymer hydrogel modules .Biomicrofluidics .2016 ,10 :014110

(8)Yihe Wang. Exploring a direct injection method for microfluidic generation of polymer microgels .Lab on a Chip .2013 ,13 (13):2547-2553

(9)Yihe Wang. Excess Molar Volumes of 1,3-Diethyl Propanedioate with Methanol, Ethanol, Propan-1-ol, Propan-2-ol, Butan-2-ol, 2-Methyl-propan-1-ol, and Pentan-1-ol at T = (288.15, 298.15, 313.15, and 328.15) K .J. Chem. Eng. Data .2010 ,55 (9):4029–4032

(10)Yihe Wang. Excess molar enthalpies of diethyl malonate+ (1-butanol, 2-methyl-1-propanol, 1-pentanol, n-heptane, and ethyl acetate) at T= (288.2, 298.2, 313.2, 328.2, 338.2, and 348.2 K) and p = 101.3 kPa .Fluid Phase Equilibria .2010 ,291 (1):8-12

(11)Yihe Wang. Excess Molar Enthalpies of Diethyl Malonate + (Methanol, + Ethanol, + 1-Propanol, and + 2-Propanol) at T = (288.2, 298.2, 313.2, and 328.2) K and p = 101.3 kPa .J. Chem. Eng. Data .2009 ,55 (1):381–384

(12)Mohammad Simchi. High-throughput sperm DNA analysis at the single-cell and population levels .Analyst .2023 ,148 :3748-3757

(13)褚玉金. Rapid and High-Throughput SARS-CoV-2 RNA Detection without RNA Extraction and Amplification by Using a Microfluidic Biochip .chemistry-a European journal .2022 ,28 (18):e202104054

(14)宋方腾. Multi-Phenotypic Exosome Secretion Profiling Microfluidic Platform for Exploring Single-Cell Heterogeneity .Small Methods .2022 ( 2200717)

(15)王超. High-Throughput, Living Single-Cell, Multiple Secreted Biomarker Profiling Using Microfluidic Chip and Machine Learning for Tumor Cell Classification .Advanced Healthcare Materials .2022 ,11 (13)

(16)Jiaoyan Qiu. Lys-AuNPs@MoS2 Nanocomposite Self-Assembled Microfluidic Immunoassay Biochip for Ultrasensitive Detection of Multiplex Biomarkers for Cardiovascular Diseases .Analytical Chemistry .2022 ,94 (11):4720-4728

(17)Elisabeth Prince. Microfluidic arrays of breast tumor spheroids for drug screening and personalized cancer therapies .Advanced Healthcare Materials .2021 ,11 (1):2101085

(18)Jae Bem You. Machine learning for sperm selection .Nat Rev Urol .2021 ,18 (7):387-403

(19)Mohammad Simchi. Selection of high-quality sperm with thousands of parallel channels .Lab on a Chip .2021 ,21 (12):2464-2475

(20)Jason Riordon. Two-Dimensional Planar Swimming Selects for High DNA Integrity Sperm .Lab on a Chip .2019 ,19 (13):2161-2167

(21)Christopher McCallum. Deep learning-based selection of human sperm with high DNA integrity .Commun Biol. .2019 ,3 (2):250

1. 一种仿生超疏水-亲水集成孔板及基于该孔板的高通量自动化核酸建库仪

1. Research on tumor drug resistance mechanism based on microfluidic biomimetic three-dimensional multicellular tumor chip and machine learning., 2020/09/18-2023/12/31

2. Research on high-throughput low-cost detection chips and systems for tumor and cerebrovascular disease markers-1, 2021/05/01-2024/06/30

3. Sensor microfluidic chip for real-time analysis of single-cell exosomes, 2021/10/12-2025/12/31

4. 小型自动化病原微生物建库仪开发及产业化, 2022/05/11-2025/05/10

5. 山东大学青年学者未来计划