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个人信息Personal Information
教授 博士生导师 硕士生导师
主要任职：山东大学附属生殖医院辅助生殖实验室主任
其他任职：山东大学附属生殖医院院长助理
性别：男
毕业院校：山东大学
学历：研究生(博士)毕业
学位：博士生
在职信息：在职
所在单位：妇儿与生殖健康研究院
入职时间：2017-09-14
学科：细胞生物学
办公地点：山东大学附属生殖医院
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- [2] . The asymmetric expression of HSPA2 in blastomeres governs the first embryonic cell-fate decision. Elife, 13, 2025.
- [3] 史明泽. SHMT2 is essential for mammalian preimplantation embryonic development through de novo biosynthesis of nucleotide metabolites. MOLECULAR THERAPY-NUCLEIC ACIDS, 36, 2025.
- [4] 张鸿惠. CHK1 controls zygote pronuclear envelope breakdown by regulating F-actin through interacting with MICAL3. EMBO Reports, 2024.
- [5] 陈晓蕾. Rescue intracytoplasmic sperm injection improved cumulative live birth rate for cycles with second polar body extrusion rate <50% in young women: generalized addictive model. Fertility and Sterility, 2024.
- [6] . The critical role of ZP genes in female infertility characterized by empty follicle syndrome and oocyte degeneration. Fertility and Sterility, 115, 1259, 2021.
- [7] 张传鑫. 2-bromoacetamide exposure impairs oocyte maturation in mice and humans primarily via disrupting the cytoskeleton. Ecotoxicology and Environmental Safety, 272, 2024.
- [8] 袁慎立. Allelic reprogramming of chromatin states in human early embryos. National Science Review, 11, 2024.
- [9] 刘玉胜. Maternal mRNA deadenylation is defective in in vitro matured mouse and human oocytes. Nature Communications, 2024.
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- [11] Yao, Xuan. Tild-CRISPR Allows for Efficient and Precise Gene Knockin in Mouse and Human Cells. Developmental Cell, 45, 526-+, 2018.
- [12] . Developmental toxicity of 2-bromoacetamide on peri- and early post-implantation mouse embryos in vitro. Ecotoxicology and Environmental Safety, 252, 2023.
- [13] . Post-ovulatory aging affects mitochondria, spindle and protein metabolism in mouse oocytes. Reproduction, 2023.
- [14] . Dynamics of histone acetylation during human early embryogenesis. CELL DISCOVERY, 9, 2023.
- [15] . Remodeling of maternal mRNA through poly(A) tail orchestrates human oocyte-to-embryo transition. Nature Structural & Molecular Biology, 30, 200-+, 2023.
- [16] 袁慎立. Human zygotic genome activation is initiated from paternal genome. CELL DISCOVERY, 9, 2023.
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- [18] . Human cleaving embryos enable robust homozygotic nucleotide substitutions by base editors. GENOME BIOLOGY, 20, 101, 2019.
- [19] Zhu, Meng. Human embryo polarization requires PLC signaling to mediate trophectoderm specification. Elife, 10, 2021.
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