Zhuanchang Wu 山东大学主页平台管理系统--Home

Zhuanchang Wu

兽医博士专业学位

Postgraduate (Doctoral)

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Gender:Male
Date of Employment:2020-04-14
Business Address:6号楼6536办公室

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Paper Publications MORE+

. Soluble Tim-3 serves as a tumor prognostic marker and therapeutic target for CD8 + T cell exhaustion and anti-PD-1 resistance. CELL REPORTS MEDICINE, 5, 2024.
. Urolithin A Hijacks ERK1/2-ULK1 Cascade to Improve CD8+ T Cell Fitness for Antitumor Immunity. Advanced Science, 2024.
武专昌. Peptide targeting the interaction of S protein cysteine-rich domain with Ezrin restricts pan-coronavirus infection. SIGNAL TRANSDUCTION AND TARGETED THERAPY, 8, 2024.
. Identification of a small-molecule Tim-3 inhibitor to potentiate T cell-mediated antitumor immunotherapy in preclinical mouse models. SCIENCE TRANSLATIONAL MEDICINE, 15, 2024.
张言坤. ZHX2 emerges as a negative regulator of mitochondrial oxidative phosphorylation during acute liver injury. NATURE COMMUNICATIONS, 14, 2024.

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. Soluble Tim-3 serves as a tumor prognostic marker and therapeutic target for CD8 + T cell exhaustion and anti-PD-1 resistance. CELL REPORTS MEDICINE, 5, 2024.

. Urolithin A Hijacks ERK1/2-ULK1 Cascade to Improve CD8+ T Cell Fitness for Antitumor Immunity. Advanced Science, 2024.

武专昌. Peptide targeting the interaction of S protein cysteine-rich domain with Ezrin restricts pan-coronavirus infection. SIGNAL TRANSDUCTION AND TARGETED THERAPY, 8, 2024.

. Identification of a small-molecule Tim-3 inhibitor to potentiate T cell-mediated antitumor immunotherapy in preclinical mouse models. SCIENCE TRANSLATIONAL MEDICINE, 15, 2024.

张言坤. ZHX2 emerges as a negative regulator of mitochondrial oxidative phosphorylation during acute liver injury. NATURE COMMUNICATIONS, 14, 2024.

一种人可溶性TIM-4蛋白在制备抗肿瘤药物中的应用

一种靶向Siglec-9促进免疫细胞抗肿瘤和抗病毒功能小分子抑制剂及其应用

一种Toll样受体激动剂纳米粒子及其制备方法和应用

一种 i-CS/HAp-NK 复合体及其制备方法和应用

一种TIM-3棕榈酰化修饰及靶向多肽在肿瘤免疫治疗中的应用

感染与免疫

感染与免疫

乙肝病毒感染临床转归关键调控网络的精准绘制及干预新策略子课题-绘制乙肝治愈和再激活的关键分子调控网络及治疗新方案, 2022-12-01-2025-11-30

Tim-3棕榈酰化修饰调控CTL/NK细胞功能耗竭的作用及机制研究, 2022-09-07-2026-12-31

Tim-3棕榈酰化修饰调控CTL/NK细胞功能耗竭的作用及机制研究, National Natural Science Foundation of China (NSFC)-2026-12-31

介导HBV肝脏免疫耐受/耗竭的关键卡控点的发现与验证, 2021-12-01-2024-11-30

Personal Information:

. Soluble Tim-3 serves as a tumor prognostic marker and therapeutic target for CD8 + T cell exhaustion and anti-PD-1 resistance. CELL REPORTS MEDICINE, 5, 2024.

. Urolithin A Hijacks ERK1/2-ULK1 Cascade to Improve CD8+ T Cell Fitness for Antitumor Immunity. Advanced Science, 2024.

武专昌. Peptide targeting the interaction of S protein cysteine-rich domain with Ezrin restricts pan-coronavirus infection. SIGNAL TRANSDUCTION AND TARGETED THERAPY, 8, 2024.

. Identification of a small-molecule Tim-3 inhibitor to potentiate T cell-mediated antitumor immunotherapy in preclinical mouse models. SCIENCE TRANSLATIONAL MEDICINE, 15, 2024.

张言坤. ZHX2 emerges as a negative regulator of mitochondrial oxidative phosphorylation during acute liver injury. NATURE COMMUNICATIONS, 14, 2024.

一种人可溶性TIM-4蛋白在制备抗肿瘤药物中的应用

一种靶向Siglec-9促进免疫细胞抗肿瘤和抗病毒功能小分子抑制剂及其应用

一种Toll样受体激动剂纳米粒子及其制备方法和应用

一种 i-CS/HAp-NK 复合体及其制备方法和应用

一种TIM-3棕榈酰化修饰及靶向多肽在肿瘤免疫治疗中的应用

感染与免疫

感染与免疫

乙肝病毒感染临床转归 关键调控网络的精准绘制及干预新策略子课题-绘制乙肝治愈和再激活的关键分子调控网络及治疗新方案, 2022-12-01-2025-11-30

Tim-3棕榈酰化修饰调控CTL/NK细胞功能耗竭的作用及机制研究, 2022-09-07-2026-12-31

Tim-3棕榈酰化修饰调控CTL/NK细胞功能耗竭的作用及机制研究, National Natural Science Foundation of China (NSFC)-2026-12-31

介导HBV肝脏免疫耐受/耗竭的关键卡控点的发现与验证, 2021-12-01-2024-11-30

乙肝病毒感染临床转归关键调控网络的精准绘制及干预新策略子课题-绘制乙肝治愈和再激活的关键分子调控网络及治疗新方案, 2022-12-01-2025-11-30