武专昌
-
副研究员
硕士生导师
- 性别：男
- 学历：研究生(博士)毕业
- 学位：兽医博士专业学位
- 在职信息：在职
- 所在单位：基础医学院
- 入职时间： 2020-04-14
- 所属院系：
齐鲁医学院
,
基础医学院
- 学科：免疫学
- 办公地点：6号楼6536办公室
访问量：
-
[1]
.
Design and biochemical evaluation of 2-cyclopropyl-thioureidobenzamide (CP-TBA) derivatives as potent HBV capsid assembly modulators targeting a novel binding site.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY,
289,
2025.
-
[2]
.
Design, Synthesis, and Biological Evaluation of Novel Thioureidobenzamide (TBA) Derivatives as HBV Capsid Assembly Modulators.
Journal of Medicianal Chemistry,
66,
2023.
-
[3]
武专昌.
cccDNA Surrogate MC-HBV-Based Screen Identifies Cohesin Complex as a Novel HBV Restriction Factor..
CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY,
14,
1177-1198,
2022.
-
[4]
张召英.
Palmitoylation of TIM-3 promotes immune exhaustion and restrains antitumor immunity.
SCIENCE IMMUNOLOGY,
9,
2024.
-
[5]
任彩月.
DNA Sensor ABCF1 Phase Separates With cccDNA to Inhibit Hepatitis B Virus Replication.
Advanced Science,
2024.
-
[6]
.
Soluble Tim-3 serves as a tumor prognostic marker and therapeutic target for CD8 + T cell exhaustion and anti-PD-1 resistance.
CELL REPORTS MEDICINE,
5,
2024.
-
[7]
.
Urolithin A Hijacks ERK1/2-ULK1 Cascade to Improve CD8+ T Cell Fitness for Antitumor Immunity.
Advanced Science,
2024.
-
[8]
武专昌.
Peptide targeting the interaction of S protein cysteine-rich domain with Ezrin restricts pan-coronavirus infection.
SIGNAL TRANSDUCTION AND TARGETED THERAPY,
8,
2023.
-
[9]
.
Identification of a small-molecule Tim-3 inhibitor to potentiate T cell-mediated antitumor immunotherapy in preclinical mouse models.
SCIENCE TRANSLATIONAL MEDICINE,
15,
2023.
-
[10]
张言坤.
ZHX2 emerges as a negative regulator of mitochondrial oxidative phosphorylation during acute liver injury.
NATURE COMMUNICATIONS,
14,
2023.
-
[11]
丁璐.
Zhx2 maintains islet β-cell mass and function by transcriptionally regulating Pax6.
iScience,
26,
106871,
2023.
-
[12]
.
Tim-4 maintains adipose tissue homeostasis by orchestrating M2 macrophage polarization via NF-κB pathway..
168,
49-62,
2022.
-
[13]
王玉珍.
TIM-4 orchestrates mitochondrial homeostasis to promote lung cancer progression via ANXA2/PI3K/AKT/OPA1 axis.
Cell Death & Disease,
14,
2023.
-
[14]
焦德雁.
Lipid accumulation-mediated histone hypoacetylation drives persistent NK cell dysfunction in anti-tumor immunity.
Cell Reports,
42,
2023.
-
[15]
武专昌.
cccDNA Surrogate MC-HBV-Based Screen Identifies Cohesin Complex as a Novel HBV Restriction Factor.
Cell Mol Gastroenterol Hepatol,
2022.
-
[16]
武专昌.
Palmitoylation of SARS-CoV-2 S protein is essential for viral infectivity.
SIGNAL TRANSDUCTION AND TARGETED THERAPY,
6,
2021.
-
[17]
p53 promotes ZDHHC1-mediated IFITM3 palmitoylation to inhibit Japanese encephalitis virus replication.
Plos Pathogens,
2020.
-
[18]
武专昌.
Tumor suppressor ZHX2 inhibits NAFLD-HCC progression via blocking LPL-mediated lipid uptake.
Cell Death and Differentiation,
27,
1693,
2020.
-
[19]
杜宪红.
Increased Tim-3 expression alleviates liver injury by regulating macrophage activation in MCD-induced NASH mice.
CELLULAR & MOLECULAR IMMUNOLOGY,
16,
878,
2019.