王瑶 (教授)

教授 博士生导师

性别:男

毕业院校:兰州大学

学位:理学博士学位

在职信息:在职

所在单位:化学与化工学院

入职时间:2015-09-17

办公地点:新化学楼331

   

个人简介


王瑶,教授,博士生导师,山东大学杰出中青年学者,获山东省杰出青年科学基金、国家优秀青年科学基金。2006年6月获兰州大学化学专业理学学士学位,2012年6月获兰州大学有机化学专业理学博士学位(导师:许鹏飞教授)。2011年1月起优博计划留任兰州大学功能有机分子化学国家重点实验室从事科研工作,在洪堡科研奖学金的支持下,2013年1月起在德国马普分子生理学研究所从事博士后研究(Hosts: Herbert Waldmann & Kamal Kumar),2015年9月至今,在山东大学化学与化工学院从事教学科研工作,目前担任中国化学会超分子化学专业委员会委员。


联系方式

电话:            0531-88361558   

Email:          yaowang@sdu.edu.cn 

地址:            山东省济南市山大南路27号新化学楼331


课题组招收博士后,欢迎申请. Fully-funded post-doc positions are available for application.

欢迎对有机化学和化学生物学感兴趣的本科生、硕士生、博士生加入本课题组.


研究方向

1. 基于弱相互作用的有机合成化学

2. 弱相互作用在功能材料合成中的应用


王瑶课题组聚焦于非经典弱相互作用催化,是国际上该领域的主要研究团队之一,主要研究成果包括:(1) 发展了普适性硫键与碳键催化剂,并阐释了其作用机制;(2)提出并发展了硫属元素相互作用催化 (chalcogen-chalcogen bonding catalysis,原始文献:JACS2019141,9175)以及硫属元素和π体系弱作用催化模式(chalcogen···π bonding catalysis,原始文献:ACIE2021, 60, 9395),发展了系列新反应,解决了反应性与选择性问题,证明了硫键催化的独特性;(3)提出并验证了碳键催化模式(carbon-bonding catalysis,原始文献:ACIE, 202160, 22717),建立了碳键金属催化策略(carbon-bonding metal catalysis, CBMC,原始文献:JACS, 2023, 145, 21554),证明了碳键作用可以调控反应性与选择性,这些研究成果拓展了弱作用的能力范畴和研究边界。



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人才计划和获奖情况

国家优秀青年科学基金 (2020)

Thieme Chemistry Journals Award (2019)   

山东省杰出青年科学基金 (2019)                      

甘肃省自然科学一等奖(2/4) (2019)  

甘肃省科技进步一等奖(7/13) (2014)          

洪堡科研奖学金 (2013) 

甘肃省自然科学一等奖(4/5) (2010)                    

宝钢奖学金(2010)                                         


发表论文/专著@SDU

Weak Interaction Activates Esters: Reconciling Catalytic Activity and Turnover Contradiction by Tailored Chalcogen Bonding.

Ziqiang Zhao, Yi Liu, Yao Wang* 

J. Am. Chem. Soc. 2024, https://doi.org/10.1021/jacs.4c01541

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Carbon-Bonding Metal Catalysis (CBMC):  A Supramolecular Complex Directs Structural-Isomer Selection in Gold-Catalyzed Reactions.

Xinxin Li, Lingfei Hu, Gang Lu*, Yao Wang* 

J. Am. Chem. Soc. 2023, 145, 39, 21554–21561.

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  • This work was highlighted as a Front Cover by JACS (link).

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Supramolecular Catalysis with Ethers Enabled by Dual Chalcogen Bonding Activation.

Zhiguo Zhao, Yuanling Pang, Ziqiang Zhao, Pan-Pan Zhou, Yao Wang* 

Nat. Commun. 2023, 14, 6347.

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Chalcogen Bonding Catalysis with Phosphonium Chalcogenide (PCH).

Zhiguo Zhao, Yao Wang* 

Acc. Chem. Res. 202356, 5, 608–621.

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Activation of Alkynes by Chalcogen Bonding: a Se⋯π Interaction Catalyzed Intramolecular Cyclization of 1,6-Diynes.

Yuanling Pang, Zhiguo Zhao, Yao Wang*  

Chem. Commun. 202359, 12278-12281. (Invited contribution)

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  • HOT Article 2023.


Chalcogen Bonding Catalysis of the Cloke─Wilson Rearrangement.

Xinglong Yuan, Lintao Bao, Zhiguo Zhao, Yao Wang* 

Chem. Eur. J. 2023 29, e202203822.

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Cooperative Chalcogen Bonding Interactions in Confined Sites Activate Aziridines.

Haofu Zhu, Pan-Pan Zhou*, Yao Wang*

Nat. Commun. 2022, 13, 3563.

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A Selenide Catalyst for the Activation of Alkenes through Se•••π Bonding.

Xinglong Yuan, Yao Wang* 

Angew. Chem. Int. Ed. 2022e202203671.


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  • This work was selected as a Hot Paper and Frontispiece (link)

  • Highlighted by Synform, 2022, A163 (link).


Wei Wang, Yao Wang*, Chalcogen Bonding Catalysis (Chapter 29), in Supramolecular Catalysis: New Directions and Developments (Editors: van Leeuwen, P. W. N. M. & Raynal, M.),  Wiley-VCH, 2022. (Invited contribution)

A Se···O bonding catalysis approach to the synthesis of calix[4]pyrroles.

Qingzhe Tong‡, Zhiguo Zhao‡, Yao Wang* (‡ equal contributors)

Beilstein J. Org. Chem. 2022, 18, 325-330. (Invited contribution)

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Catalysis with Supramolecular Carbon-Bonding Interactions.

Wei Wang, Xinxin Li, Pan-Pan Zhou, Yao Wang* 

Angew. Chem. Int. Ed. 2021, 60, 22717–22721.

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Chalcogen•••π Bonding Catalysis.

Xiangjin Kong, Pan-Pan Zhou, Yao Wang* 

Angew. Chem. Int. Ed. 2021, 60, 9395-9400.

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Direct Use of Unprotected Aliphatic Amines to Generate N-Heterocycles via β-C–H Malonylation with Iodonium Ylide. 

Zhiguo Zhao, Xiangjin Kong, Wei Wang, Jingcheng Hao, Yao Wang*

Org. Lett. 2020, 22, 230-233.


Noncovalent Chalcogen‐Bonding Catalysis Using ppm‐Level Catalyst Loading to Achieve Cyanosilylation of Ketones.

Lintao Bao, Xiangjin Kong, Yao Wang*

Asian J. Org. Chem. 2020, 9, 757-760 

  • Cover Feature: ppm-Level Catalysis in a Sigma-Hole World.


Dual Chalcogen-Chalcogen Bonding Catalysis.

Wei Wang, Haofu Zhu, Lei Feng, Qun Yu, Jingcheng Hao, Rongxiu Zhu, Yao Wang*

J. Am. Chem. Soc. 2020, 142, 3117-3124.



Chalcogen–Chalcogen Bonding Catalysis Enables Assembly of Discrete Molecules.

Wei Wang, Haofu Zhu, Shuya Liu, Zhiguo Zhao, Liang Zhang, Jingcheng Hao, Yao Wang*

J. Am. Chem. Soc. 2019, 141, 9175-9179.

     

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Succinimide-Promoted Malonylamination of Alkenes with Amines and Iodonium Ylides via Trapping of Transient Aminium Radical Cations.

Liang Zhang, Xiangjin Kong, Shuya Liu, Zhiguo Zhao, Qun Yu, Wei Wang, Yao Wang*

Org. Lett. 2019, 21, 2923-2926.



Construction of N‐Heterocycles through Cyclization of Tertiary Amines.

Shuya Liu, Zhiguo Zhao, Yao Wang*

Chem. Eur. J. 2019, 25, 2423-2441. (Invited contribution)


Uncovering Multifaceted Iodonium Ylides: Versatile Reactivity Enables Cyclization of Simple Arylamines.

Liang Zhang, Yao Wang*

Synlett 2018, 29, 2337–2341. (Invited Synpacts Highlight)

(Salen)Mn(III)-Catalyzed Chemoselective Acylazidation of Olefins.

Liang Zhang, Shuya Liu, Zhiguo Zhao, Hongmei Su, Jingcheng Hao, Yao Wang*

Chem. Sci. 2018, 9, 6085-6090.

  • RSC主编推荐为有机领域精彩文章https://www.x-mol.com/news/13341

Direct Cyclization of Tertiary Aryl Amines with Iodonium Ylides.

Zhiguo Zhao, Yongrui Luo, Shuya Liu, Liang Zhang, Lei Feng, Yao Wang*

Angew. Chem. Int. Ed. 2018, 57, 3792-3796.



  • ACIE 2018年3月Top 10 Most Accessed Article

  • Highlighted by Synpacts

  • Highlighted by Chin. J. Org. Chem. 

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Selected Publications Before SDU

Yao Wang, Hong Lu, Peng-Fei Xu*, Asymmetric Catalytic Cascade Reactions for Constructing Diverse Scaffoldsand Complex Molecules.

Acc. Chem. Res. 2015, 48, 1832-1844.

 

Yun Gu#, Yao Wang#, Yong-Min Liang, Peng-Fei Xu*, Rationally Designed Multifunctional Supramolecular Iminium Catalysis: the Direct Vinylogous Michael Addition with Unmodified Linear Dienol Substrates.

Angew. Chem. Int. Ed. 2014, 53, 14128–14131. (#:Co-first author.)


Yao Wang, Jonathan O. Bauer, Carsten Strohmann, Kamal Kumar*, A Bioinspired Catalytic Oxygenase Cascade to Generate Complex Oxindoles.

Angew. Chem. Int. Ed. 2014, 53, 7514–7518.

 

Yao Wang, Tian-Yang Yu, Hong-Bo Zhang, Yong-Chun Luo, Peng-Fei Xu*, Hydrogen-Bond-Mediated Supramolecular Iminium Ion Catalysis.

Angew. Chem. Int. Ed. 2012, 51, 12339–12342.

(Highlighted by Synfacts and Chin. J. Org. Chem.)

 

Yao Wang, Rong-Gang Han, Yong-Long Zhao, Shu Yang, Peng-Fei Xu* and Darren J. Dixon*, Asymmetric Organocatalytic Relay Cascades: Catalyst-Controlled Stereoisomer Selection in the Synthesis of Functionalized Cyclohexanes.

Angew. Chem. Int. Ed. 2009, 48, 9834–9838.

(Highlighted by Synfacts and Chin. J. Org. Chem.)   

教育经历

[1]   2006.9-2012.6

兰州大学  |  有机化学  |  理学博士学位

[2]   2002.9-2006.6

兰州大学  |  化学  |  理学学士学位