Scientific Research
Working-Papers
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Paper Publications
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. Dual targeting PPARα and NPC1L1 metabolic vulnerabilities blocks tumorigenesis. Cancer letters, 612, 2025.
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. HDAC11 Inhibition as a Potential Therapeutic Strategy for AML: Target Identification, Lead Discovery, Antitumor Potency, and Mechanism Investigation. Journal of Medicinal Chemistry, 2025.
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. MFSD7C protects hemolysis-induced lung impairments by inhibiting ferroptosis. NATURE COMMUNICATIONS, 15, 2025.
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. Discovery of epigenetic modulators targeting HDACs and EZH2 simultaneously for the treatment of hematological malignancies. Bioorganic Chemistry, 153, 2025.
Patents
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Research Projects
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(包干项目)谷氨酰胺代谢在急性髓系白血病患者 吉瑞替尼耐药中的作用和机制研究 , 2025-05-01 -2028-04-30
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PADI2在急性髓系白血病糖代谢重编程及化疗敏感性中的作用及分子机制研究 , 2024-08-23 -2028-12-31
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NrasG12D与Asxl1G643WfsX12协同参与慢性粒单核细胞白血病急性转化的机制及治疗研究 , 2022-09-07 -2026-12-31
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(包干项目)白血病发生发展机制研究及靶向治疗 , 2022-03-30 -2025-03-01
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(包干项目)Sos1变构位点作为Kras介导的血液恶性肿瘤治疗靶点的研究 , 2021-10-12 -2024-12-31
Research Team
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