于晓强

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Biography

于晓强教授个人经历介绍

于晓强博士 山东大学晶体材料国家重点实验室教授，学术带头人，博士生导师 先后 承担1项国家重大科学研究计划项目-973子课题、1项国家自然科学基金/香港资助局  联合基金、4项国家自然科学基金、1项山东省自然科学基金重大基础研究项目和1项山东省自然科学基金重点项目，发表高水平论文30余篇，专利10余件。

主要研究方向：

     （1）活细胞荧光探针

     （2）双光子荧光探针

     （3）生物组织荧光探针

     （4）细胞器与代谢分子荧光探针

     （5）肿瘤诊断荧光探针

 教育经历：

1999/7-2001/7，山东大学，博士后，合作导师：蒋民华院士

1996/9–1999/7， 吉林大学， 物理化学，    博士，  导师：孙家钟院士、汤心颐教授

1985/9–1988/7， 清华大学， 化学工程与应用化学，    硕士，   导师：孙以实教授

1981/9–1985/7， 吉林大学， 高分子化学与物理，     学士，   指导老师：张雪松副教授

科研与学术工作经历：

2001/7-至今，山东大学，晶体材料研究所，副教授、教授、博士生导师

1988/9-1996/9，山东工业大学，材料科学与工程系，讲师

Email:yuxq@sdu.edu.cn .

课题组热烈欢迎具有化学、材料、生物以及多学科交叉背景的硕士、博士和博士后加入，每年拟招生1-2名硕士和1-2名博士。有意者请发邮件至yuxq@sdu.edu.cn .

课题组网站：https://faculty.sdu.edu.cn/kytdcnmb3/index.ID446675.jsp?wbtreeid=1022&tstreeid=89B2094E66514B30B56004E9DC5FE452&_t_uid=41993&a=ID446675&h=-1628893899&language=zh_CN&homepageuuid=7134AF30C5D2439EA87FF8C35D5397A1&templateuuid=A104E950731B48C89EE0B8AE184C02D4&producttype=4&_tmode_=99&tsitesapptype=index

Education Background

• 1981-09-01-1985-07-01
  吉林大学
  高分子化学
• 1985-09-01-1987-07-01
  清华大学
  应用化学
• 1996-09-01-1999-07-01
  吉林大学
  物理化学

Work Experience

• 1999-09 — Now
  山东大学晶体材料研究所
• 1987-07 — 1996-09
  山东工业大学

Publication

Research direction

1. 功能荧光材料的设计、合成及其在生物医学成像中的应用​

2. 材料科学类

Papers

(1)孟芳芳. Simultaneous visualization of lipid droplets and lysosomes using a single fluorescent probe .SENSORS AND ACTUATORS B-CHEMICAL .2020 (129148)

(2)曹世仙. Super-Resolution FLIM Imaging of Intracellular Lipid Microenvironments with a Dual-Responsive Polarity-and pH Sensitive Fluorescent Probe .ANALYTICAL CHEMISTRY .2025 (24)

(3)王雨梦. Lighting Up Nucleolus To Report Mitochondria Damage Using a Mitochondria-to-Nucleolus Migration Probe .ANALYTICAL CHEMISTRY .2024 (24)

(4) Simultaneous multi-color visualizing and real-time monitoring of cellular viscosity during ferroptosis via fluorescence lifetime microscopy .SENSORS AND ACTUATORS B-CHEMICAL .2025 (138116)

(5)曹明月. Ultra Photostable Fluorescent Boron-Bridged Near-Infrared Probes to Reveal New Mode of Lipid Droplet-Mitochondria Interaction at STED Super-Resolution .ANALYTICAL CHEMISTRY .2025 (30)

(6) Novel fluorescent probes for highly selective two-photon imaging of mitochondria in living cells .Biosensors & Bioelectronics .2013 (55)

(7) Low molecular weight fluorescent probes with good photostability for imaging RNA-rich nucleolus and RNA in cytoplasm in living cells .Biomaterials .2013 ,35 (7):2103

(8)郭丽方. Simultaneous Two-Color Visualization of Lipid Droplets and Endoplasmic Reticulum and Their Interplay by Single Fluorescent Probes in Lambda Mode .Journal of the American Chemical Society .2021 (143)

(9)张革. Red-Emitting Mitochondrial Probe with Ultrahigh Signal-to-Noise Ratio Enables High-Fidelity Fluorescent Images in Two-Photon Microscopy .ANALYTICAL CHEMISTRY .2015 (24)

(10)盛南. Changing complexity into simplicity: visualization of endoplasmic reticulum autophagy employing a self-deliver viscosity sensor by lifetime imaging. .Biosensors and Bioelectronics .2025 (5)

(11)程淼. High photostability probes for tagging mitochondrial cristae via STED microscopy .SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY .2025 ,343

(12)金文东. Simultaneous multi-color visualizing and real-time monitoring of cellular viscosity during ferroptosis via fluorescence lifetime microscopy .SENSORS AND ACTUATORS B-CHEMICAL .2025 ,442

(13) Spatiotemporal Super-Resolution Imaging of Lipid Metabolism Dynamics in Physiological/Pathological Conditions .ANGEWANDTE CHEMIE-INTERNATIONAL EDITION .2025 ,64 (29)

(14)金文东. A novel small-molecule fluorescent probe caused by minimal structural modifications for specific staining of the cell nuclear membrane .Chemical communication .2025

(15)Liu, Yang. Dual-targeted fluorescent probe for tracking polarity and phase transition processes during lipophagy .MATERIALS HORIZONS .2024 ,11 (14)

(16)苏彦刚. Harnessing an MMP-Independent NIR Probe Unveiling the Different Mitochondrial Cristae Changes during Mitophagy and Ferroptosis under STED Microscopy .ANALYTICAL CHEMISTRY .2025 ,97 (5):2906-2913

(17)金文东. Ultra-photostable fluorescent dye molecular engineering-for measuring plant cells' membrane-spacing through a deposition-embedding strategy .Journal of Materials Chemistry B .2025

(18)吕卿. Self-Referenced Probe Enables Quantified Monitoring Mitochondrial Membrane Potential by Colocalization Coefficients .ANALYTICAL CHEMISTRY .2025

(19)Meng, Fangfang. Real-time and in situ visualizing the details of mitochondrial fragmentation with a leakage-free fluorescent probe in living cells .SENSORS AND ACTUATORS B-CHEMICAL .2023 ,393

(20)牛杰. Tiny nuance leads to large difference: Construction of fluorescent probes to visualize early and late apoptotic stages .SENSORS AND ACTUATORS B-CHEMICAL .2023 ,393

(21)付金玉. An ultra-photostable and leakage-free fluorescent probe for long-term and high-fidelity mitochondria visualization and tracking .Dyes and Pigments .2023 ,216

(22)宗冲. A fluorescent probe for detecting mitochondrial viscosity and its application in distinguishing human breast cancer cells from normal ones .Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy .2023 ,299

(23)Meng, Fangfang. Simultaneous visualization of lipid droplets and lysosomes using a single fluorescent probe .SENSORS AND ACTUATORS B-CHEMICAL .2020 ,329

(24)Guo, Lifang. Development of reaction-free and mitochondrion-immobilized fluorescent probe for monitoring pH change .SENSORS AND ACTUATORS B-CHEMICAL .2021 ,341

(25)王嘉萱. Linearly Polarized Broadband Emission and Multiwavelength Lasing in Solution-Processed Quantum Dots .ADVANCED MATERIALS .2024 (2024)

(26)李驰. Polyvalent anion-induced J-aggregation and its use in ratiometric fluorescence tracking of hypotonic in Arabidopsis .SENSORS AND ACTUATORS B-CHEMICAL .2023 (无)

(27) Long-Chain Fluorescent Probe for Straightforward and Nondestructive Staining Mitochondria in Fixed Cells and Tissues .ANALYTICAL CHEMISTRY .2024

(28)吕星宇. A hydrophilic lysosome-nucleolus immigration fluorescent probe for tracking normal cells from apoptosis to necrosis .SENSORS AND ACTUATORS B-CHEMICAL .2024 ,406

(29)周士敏. Synthesis, Structures, and Photophysical Properties of Zigzag BNBNB-Embedded Anthracene-Fused Fluoranthene .organic letters .2023 ,25 (9):1573-1577

(30)刘阳. Engineering hydrophilic/hydrophobic moieties of ratiometric fluorescence probe to visualize whole cytoplasmic polarity .Chemical Engineering Journal .2023 ,459 (无)

(31)周士敏. Dimesitylboryl-ended oligothiophene with tetrazine as core: Synthesis, structure and Diels–Alder reactivity .CHINESE CHEMICAL LETTERS .2023 (2024):108325

(32)余志超. Mechanistic investigation on up and down conversion of Er3+ and Gd3+ co-doped YTiNbO6 Phosphors .RSC advances .2015 (5):94607

(33)郭鹏. Luminescence, energy transfer, colour modulation and up-conversion mechanisms of Yb3+, Tm3+ and Ho3+ co-doped Y6MoO12 .RSC advances .2022 (12):33419

(34)孟芳芳. A dual-targeting fluorescent probe for simultaneous and discriminative visualization of lipid droplets and endoplasmic reticulum .Journal of Materials Chemistry B .2022 ,10 (43):8875-8882

(35)杨锐. Long-term tracking of endoplasmic reticulum autophagy by a fluorescent probe with a long alkyl chain .SENSORS AND ACTUATORS B-CHEMICAL .2022 ,372

(36)王嘉萱. Enhanced Long-Term Luminescent Stability through Near-Single-Dot Passivation and Encapsulation of Perovskite Quantum Dots for Printable Photonics .SMALL STRUCTURES .2023

(37)刘阳. Engineering hydrophilic/hydrophobic moieties of ratiometric fluorescence probe to visualize whole cytoplasmic polarity .Chemical Engineering Journal .2023 (459):141651

(38)牛杰. A self-reporting photosensitizer for inducing and in-situ monitoring lysosomal damage and cell apoptosis .SENSORS AND ACTUATORS B-CHEMICAL .2023 (382):133482

(39)牛广乐. Specific Two-Photon Imaging of Live Cellular and Deep-Tissue Lipid Droplets by Lipophilic AIEgens at Ultralow Concentration .Chemistry of Material .2018 (14):4778

(40)王嘉萱. Enhanced Long-Term Luminescent Stability through Near-Single-Dot Passivation and Encapsulation of Perovskite Quantum Dots for Printable Photonics .Small Structures .2023 (3):2200391

(41)孙丰磊. Upconversion photoluminescent Yb(Ⅲ)/Er(Ⅲ) doped nanoparticles interact with AuNPs for detection of Cr (Ⅲ) and sodium tripolyphosphate based on FRET .OPTICAL MATERIALS .2022 (128):112392

(42)牛杰. Ratiometric and Discriminative Visualization of Autophagy and Apoptosis with a Single Fluorescent Probe Based on the Aggregation/Monomer Principle .ANALYTICAL CHEMISTRY .2022 (94):17885

(43)李驰. Probing mitochondrial damage using a fluorescent probe with mitochondria-to-nucleolus translocation .CHINESE CHEMICAL LETTERS .2023 (S1001841723001857):108323

(44)杨锐. Long-term tracking of endoplasmic reticulum autophagy by a fluorescent probe with a long alkyl chain .SENSORS AND ACTUATORS B-CHEMICAL .2022 (372)

(45)牛杰. Isomeric probes for monitoring mitochondrial membrane potential under fluorescence lifetime imaging microscopy .SENSORS AND ACTUATORS B-CHEMICAL .2022 (372)

(46)郭鹏. Luminescence, energy transfer, colour modulation and up-conversion mechanisms of Yb 3+ , Tm 3+ and Ho 3+ co-doped Y 6 MoO 12 .RSC advances .2022 (51)

(47)曹明月. Structure Rigidification Promoted Ultrabright Solvatochromic Fluorescent Probes for Super-Resolution Imaging of Cytosolic and Nuclear Lipid Droplets .ANALYTICAL CHEMISTRY .2022 ,94 (30):10676-10684

(48)李阳. Temperature Dependence of the Thermal, Electrical Resistivity, Dielectric and Piezoelectric Properties of CaYAl3O7 Crystal .Crystals .2018 ,8 (1):1

(49)蒋震. Synthesis, Structure, and Photophysical Properties of BN-Embedded Analogue of Coronene .Organic Letters .2022 ,24 (4):1017

(50)张华淼. Permeability-Controllable Potentiometric Fluorescent Probes Enable Visually Discriminating Near-Zero and Normal Situations of Cell Membrane Potential .ANALYTICAL CHEMISTRY .2021 ,93 (5):2728

(51)杨锐. Fabrication of small-structure red-emissive fluorescent probes for plasma membrane enables quantification of nuclear to cytoplasmic ratio in live cells and tissues .Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy .2021 ,249

(52)郝秋华. Construction of fluorescent rotors with multiple intramolecular rotation sites for visualization of cellular viscous compartments with elevated fidelity .Analytical methods .2021 ,13 (9):1132

(53)李学晨. Two-Color Visualization of Cholesterol Fluctuation in Plasma Membranes by Spatial Distribution-Controllable Single Fluorescent Probes .ANALYTICAL CHEMISTRY .2021 ,93 (26):9074

(54)孟芳芳. A pH-Sensitive Spirocyclization Strategy for Constructing a Single Fluorescent Probe Simultaneous Two-Color Visualizing of Lipid Droplets and Lysosomes and Monitoring of Lipophagy .ANALYTICAL CHEMISTRY .2021 ,93 (34):11729

(55)宋海宁. Inner filter effect between upconversion nanoparticles and Fe(II)–1,10-phenanthroline complex for the detection of Sn(II) and ascorbic acid (AA) .RSC advances .2021 (11):17212

(56)李泽欣. Warm white-light emitting silica films prepared using lead-free double perovskite QDs .Dalton Transcations .2021 (50):9804

(57)周森浩. Syntheses, structures, and one- and two-photon excited fluorescence of dimesitylboryl-ended quadrupolar hybrid oligothiophenes .New J. Chem. .2021

(58)于晓强. Interface-Targeting Strategy Enables Two-Photon Fluorescent Lipid Droplet Probes for High-Fidelity Imaging of Turbid Tissues and Detecting Fatty Liver .ACS Applied Materials & Interfaces .2018 (10)

(59)于晓强. A small-structure two-photon platform equipped with weak electron donor: Development of permeable two-photon probes for lysosomes and mitochondria in living cells .SENSORS AND ACTUATORS B-CHEMICAL .2016 (243)

(60)于晓强. Spatially Dependent Fluorescent Probe for Detecting Different Situations of Mitochondrial Membrane Potential Conveniently and Efficiently .Anal. Chem. .2017 (89)

(61)于晓强. A general strategy to increase emission shift of two-photon ratiometric pH probes using a reversible intramolecular reaction of spiro-oxazolidine .Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy .2020 (246)

(62)于晓强. Phospholipid-Biomimetic Fluorescent Mitochondrial Probe with Ultrahigh Selectivity Enables In Situ and High-Fidelity Tissue Imaging .ANALYTICAL CHEMISTRY .2017 (89)

(63)于晓强. A single fluorescent probe enables clearly discriminating and simultaneously imaging liquid-ordered and liquid-disordered microdomains in plasma membrane of living cells .Biomaterials .2016 (120)

(64)于晓强. Styrylpyridine salts-based red emissive two-photon turn-on probe for imaging the plasma membrane in living cells and tissues .Analyst .2016 (141)

(65)张华淼. A general strategy to increase emission shift of two-photon ratiometric pH probes using a reversible intramolecular reaction of spiro-oxazolidine .Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy .2020 ,246 (246)

(66)马保金. One-Dimensional Hydroxyapatite Nanostructures with Tunable Length for Efficient Stem Cell Differentiation Regulation .ACS Applied Materials & Interfaces .2017 (39):33717

(67)郭丽方. A side-chain engineering strategy for constructing fluorescent dyes with direct and ultrafast self-delivery to living cells .Chemical Science .2020 ,11 (3):661

(68)芦青. Comparison Study of the Site-Effect on Regioisomeric Pyridyl- Pyrene Conjugates: Synthesis, Structures, and Photophysical Properties .The Journal of Organic Chemistry .2020 ,85 (6):4256

(69)周士敏. Synthesis, structure, and aggregated state emission of regio-isomeric 3-Pyrenyl-2-(4 '-Pyridinyl)-Acrylonitrile .JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY .2020 ,389

(70)李阳. Optimizing growth, structure, and elastic-electrical properties of acentric melilite CaYAl3O7 crystals .Journal of Alloy and Compounds .2018 ,748 (0):57

(71)李阳. Temperature dependence of the thermal, electrical resistivity, dielectric and piezoelectric properties of CaYAl3O7 crystals .Crystals .2018 ,8 (1):1

(72)于晓强. Permeability-Controllable Potentiometric Fluorescent Probes Enable Visually Discriminating Near-Zero and Normal Situations of Cell Membrane Potential .ANALYTICAL CHEMISTRY .2021 ,93 (5):2728

(73)于晓强. A Single Fluorescent pH Probe for Simultaneous Two-Color Visualization of Nuclei and Mitochondria and Monitoring Cell Apoptosis .ACS SENSORS .2021 ,6 (4):1552

(74)于晓强. Simultaneous Two-Color Visualization of Lipid Droplets and Endoplasmic Reticulum and Their Interplay by Single Fluorescent Probes in Lambda Mode . J. Am. Chem. Soc. .2021 ,143 (8):3169

(75) Simultaneous Two-Color Visualization of Lipid Droplets and Endoplasmic Reticulum and Their Interplay by Single Fluorescent Probes in Lambda Mode .Journal of the American Chemical Society .2021 ,143 (8):3169

(76) A Single Fluorescent pH Probe for Simultaneous Two-Color Visualization of Nuclei and Mitochondria and Monitoring Cell Apoptosis .ACS sensors .2021

(77) Permeability-Controllable Potentiometric Fluorescent Probes Enable Visually Discriminating Near-Zero and Normal Situations of Cell Membrane Potential .Analytical chemistry .2021 ,93 (5):2728

(78) Simultaneous visualization of lipid droplets and lysosomes using a single fluorescent probe .Sensors and actuators. B-Chemical .2021 ,329

(79) Comparison Study of the Site-Effect on Regioisomeric Pyridyl-Pyrene Conjugates: Synthesis, Structures, and Photophysical Properties .Journal of organic chemistry .2020 ,85 (6):4256

(80) A side-chain engineering strategy for constructing fluorescent dyes with direct and ultrafast selfdelivery to living cells .Chemical science .2019 ,11 (3):661

(81) Colocalization Coefficients of a Target-Switchable Fluorescent Probe Can Serve As an Indicator of Mitochondrial Membrane Potential .Analytical chemistry .2019 ,91 (4):2672

(82) Modulate the structures and photophysical properties of pyrene-based far-red fluorescent cationic dyes by regio-effect .SENSORS AND ACTUATORS B-CHEMICAL .2018 ,276 :331

(83) Reaction-free and MMP-independent fluorescent probes for long-term mitochondria visualization and tracking. .Chemical science .2018 ,10 (7):1994

(84) Colocalization Coefficients of a Target-Switchable Fluorescent Probe Can Serve As an Indicator of Mitochondrial Membrane Potential .Analytical chemistry .2018 ,91 (4):2672

(85) Interface-Targeting Strategy Enables Two-Photon Fluorescent Lipid Droplet Probes for High-Fidelity Imaging of Turbid Tissues and Detecting Fatty Liver .ACS applied materials & interfaces .2018 ,10 (13):10706

(86) Nonlinear optical property and ultrafast response of a two-photon photopolymerization initiator based on dibenzothiophene .Journal of nonlinear optical physics & materials .2017 ,26 (4):1750048

(87) Two-photon fluorescent probe for detecting cell membranal liquid-ordered phase by an aggregate fluorescence method .Journal of materials chemistry. B-Materials for biology and medicine .2017 ,5 (24):4725

(88) Phospholipid-Biomimetic Fluorescent Mitochondrial Probe with Ultrahigh Selectivity Enables In Situ and High-Fidelity Tissue Imaging .Analytical chemistry .2017 ,89 (12):6575

(89) Spatially Dependent Fluorescent Probe for Detecting Different Situations of Mitochondrial Membrane Potential Conveniently and Efficiently .Analytical chemistry .2017 ,89 (6):3335

(90) A small-structure two-photon platform equipped with weak electron donor: Development of permeable two-photon probes for lysosomes and mitochondria in living cells .Sensors and actuators. B-Chemical .2017 ,243 :955

(91) A single fluorescent probe enables clearly discriminating and simultaneously imaging liquid-ordered and liquid-disordered microdomains in plasma membrane of living cells .Biomaterials .2017 ,120 :46

(92) Spatially Dependent Fluorescent Probe for Detecting Different Situations of Mitochondrial Membrane Potential Conveniently and Efficiently .Analytical chemistry .2017 ,89 (6):3335

(93) Styrylpyridine salts-based red emissive two-photon turn-on probe for imaging the plasma membrane in living cells and tissues .Analyst .2016 ,141 (11):3228

(94) Two-photon fluorescent probe for detecting cell membranal liquid-ordered phase by an aggregate fluorescence method .Journal of materials chemistry. B-Materials for biology and medicine .2016 ,5 (24):4725

(95) A photostable fluorescent probe for rapid monitoring and tracking of a trans-membrane process and mitochondrial fission and fusion dynamics .New journal of chemistry .2016 ,40 (4):3726

(96) 4-tert-Butylphenoxy substituted phthalocyanine with RGD motif as highly selective one-photon and two-photon imaging probe for mitochondria and cancer cel .Journal of porphyrins and phthalocyanines .2016 ,20 (1-4):397

(97) A dual-site two-photon fluorescent probe for visualizing mitochondrial aminothiols in living cells and mouse liver tissues .New journal of chemistry .2016 ,40 (9):7399

(98) Red-Emitting Mitochondrial Probe with Ultrahigh Signal-to-Noise Ratio Enables High-Fidelity Fluorescent Images in Two-Photon Microscopy .Analytical chemistry .2015 ,87 (24):12088

(99)于晓强. Red-Emitting Mitochondrial Probe with Ultrahigh Signal-to-Noise Ratio Enables High-Fidelity Fluorescent Images in Two-Photon Microscopy .Anal. Chem. .2015 ,87 (24):12088

(100)于晓强. Red-Emitting Mitochondrial Probe with Ultrahigh Signal-to-Noise Ratio Enables High-Fidelity Fluorescent Images in Two-Photon Microscopy .Anal. Chem. .2015 ,87 (24):12088

(101)于晓强. A membrane-permeable dye for living cells with large two-photon excited fluorescence actioncross-sections for bioimaging .J. Mater. Chem. B .2015 ,3 (44):8644

(102)于晓强. A membrane-permeable dye for living cells with large two-photon excited fluorescence actioncross-sections for bioimaging .J. Mater. Chem. B .2015 ,3 (44):8644

(103)于晓强. Red-Emitting Mitochondrial Probe with Ultrahigh Signal-to-Noise Ratio Enables High-Fidelity Fluorescent Images in Two-Photon Microscopy .Anal.chem. .2015

(104)周广军. Mechanistic investigation on up and down conversion of Er3+ and Gd3+ co-doped YTiNbO6 Phosphors .RSC advances .2015 ,5 :94607

(105)周广军. Mechanistic investigation on up and down conversion of Er3+ and Gd3+ co-doped YTiNbO6 Phosphors .RSC advances .2015 ,5 :94607

(106)周广军. Mechanistic investigation on up and down conversion of Er3+ and Gd3+ co-doped YTiNbO6 Phosphors .RSC advances .2015 ,5 :94607

(107)周广军. Mechanistic investigation on up and down conversion of Er3+ and Gd3+ co-doped YTiNbO6 Phosphors .RSC advances .2015 ,5 :94607

(108)王正平. Nonlinear optical characterizations of monoclinic LaxGd1？xCa4O(BO3)3 (x = 1, 0.09, 0.13) single crystals .2015

(109)王正平. Nonlinear optical characterizations of monoclinic LaxGd1-xCa4O(BO3)3 (x = 1, 0.09, 0.13) single crystals .Laser Physics Letters .2014 ,25

(110)王正平. Nonlinear optical characterizations of monoclinic LaxGd1？xCa4O(BO3)3 (x = 1, 0.09, 0.13) single crystals .Laser Physics .2014 ,25 :015804

(111)于晓强. A two-photon ratiometric ？uorescent probe enables spatial coordinates determination of intracellular pH .Talanta .2014 ,129 :241

(112)于晓强. A two-photon ratiometric ？uorescent probe enables spatial coordinates determination of intracellular pH .Talanta .2014 ,129 :241

(113)王正平. High efficiency angular non-critical phase matching for Ti:sapphire laser realized on LaCa4O(BO3)3 single crystals .Laser Physics Letters .2014

(114)于晓强. A fluorescent probe for intracellular cysteine overcoming the interference by glutathione .Org. Biomol. Chem .2014 ,12 :6128

(115)于晓强. A fluorescent probe for intracellular cysteine overcoming the interference by glutathione .Org. Biomol. Chem .2014 ,12 :6128

(116)王正平. High efficiency angular non-critical phase matching for Ti:sapphire laser realized on LaCa4O(BO3)3 single crystals .laser physics letters .2014 ,11 :095403

(117)王正平. High efficiency angular non-critical phase matching for Ti:sapphire laser realized on LaCa4O(BO3)3 single crystals .Laser Physics Letters .2014 ,11

(118)于晓强. Two-photon ？uorescence imaging of RNA in nucleoli and cytoplasm in living cells based on low molecular weight probes .Dyes and pigments .2014 ,103 :191

(119)于晓强. Two-photon ？uorescence imaging of RNA in nucleoli and cytoplasm in living cells based on low molecular weight probes .Dyes and pigments .2014 ,103 :191

(120)于晓强. Novel ？uorescent probes for highly selective two-photon Imaging of mitochondria in living cells .Biosensors & Bioelectronics .2014 ,55 :423

(121)于晓强. Novel ？uorescent probes for highly selective two-photon Imaging of mitochondria in living cells .Biosensors and Bioelectronics .2014 ,55 :423

(122)于晓强. Low molecular weight fluorescent probes with good photostability for imaging RNA-rich nucleolus and RNA in cytoplasm in living cells .Biomaterials .2014 ,35 (7):2103

(123)于晓强. Low molecular weight fluorescent probes with good photostability for imaging RNA-rich nucleolus and RNA in cytoplasm in living cells .Biomaterials .2014 ,35 (7):2103

(124)于晓强. Lighting up cysteine and homocysteine in sequence based on the kinetic difference of the cyclization/addition reaction .Organic & Biomolecular Chemistry .2013 ,11 (44):7721

(125)于晓强. Lighting up cysteine and homocysteine in sequence based on the kinetic difference of the cyclization/addition reaction .Organic & Biomolecular Chemistry .2013 ,11 (44):7721

(126)于晓强. Fluorescent imaging of acidic compartments in living cells with a high selective novel one-photon ratiometric and two-photon acidic pH probe .Biosensors & Bioelectronics .2013 ,50 :42

(127)于晓强. Fluorescent imaging of acidic compartments in living cells with a high selective novel one-photon ratiometric and two-photon acidic pH probe .Biosensors and Bioelectronics .2013 ,50 :42

(128)于晓强. Synthesis, One- and Two-Photon Photophysical and Excited-State Properties, and Sensing Application of a New Phosphorescent Dinuclear Cationic Iridium(III) .Chemistry-A European Journal .2013 ,19 :620

(129)于晓强. Synthesis, One- and Two-Photon Photophysical and Excited-State Properties, and Sensing Application of a New Phosphorescent Dinuclear Cationic Iridium(III) .Chemistry-A European Journal .2013 ,19 :620

(130)吴拥中. CdTe量子点的微波合成及其在双光子显微成像中的应用 .《功能材料》 .2012 ,43 (15):2035

(131)吴拥中. CdTe量子点的微波合成及其在双光子显微成像中的应用 .《功能材料》 .2012 ,43 (15):2035

(132)吴拥中. CdTe量子点的微波合成及其在双光子显微成像中的应用 .《功能材料》 .2012 ,43 (15):2035

(133)苗芳. Fluorescence turn-on probes for intracellular RNA distribution and their imaging in confocal and two-photon fluorescence microscopy .Sensor. Actuat. B-Chem .2012 ,173 :329

(134)苗芳. Fluorescence turn-on probes for intracellular RNA distribution and their imaging in confocal and two-photon fluorescence microscopy .2012 ,173 :329

(135)苗芳. Fluorescence turn-on probes for intracellular RNA distribution and their imaging in confocal and two-photon fluorescence microscopy .2012 ,173 :329

(136)苗芳. Fluorescence turn-on probes for intracellular RNA distribution and their imaging in confocal and two-photon fluorescence microscopy .Sensor. Actuat. B-Chem .2012 ,173 :329

(137)宋国芬. Highly selective red- and green-emitting two-photon fluorescent probes for cysteine detection and their bio-imaging in living cells .2012 ,48 :3442

(138)宋国芬. Highly selective red- and green-emitting two-photon fluorescent probes for cysteine detection and their bio-imaging in living cells .Chem. Commun .2012 ,48 :3442

(139)宋国芬. Highly selective red- and green-emitting two-photon fluorescent probes for cysteine detection and their bio-imaging in living cells .Chem. Commun .2012 ,48 :3442

(140)于晓强. Highly selective red- and green-emitting two-photon fluorescent probes for cysteine detection and their bio-imaging in living cells .chem. commun. .2012 ,48 (28 ):3442

(141)于晓强. Highly selective red- and green-emitting two-photon fluorescent probes for cysteine detection and their bio-imaging in living cells .chem. commun. .2012 ,48 (28 ):3442

(142)赵红石. A 2,7-carbazole-based dicationic salt for fluorescence detection of nucleic acids and two-photon fluorescence imaging of RNA in nucleoli and cytoplasm . Org. Biomol. Chem .2011 ,9 (10):3615

(143)赵红石. A 2,7-carbazole-based dicationic salt for fluorescence detection of nucleic acids and two-photon fluorescence imaging of RNA in nucleoli and cytoplasm .2011 ,9 (10):3615

(144)赵红石. A 2,7-carbazole-based dicationic salt for fluorescence detection of nucleic acids and two-photon fluorescence imaging of RNA in nucleoli and cytoplasm .Org. Biomol. Chem .2011 ,9 (10):3615

(145)刘鑫. A Series of Carbazole Cationic Compounds with Large Two-Photon Absorption Cross Sections for Imaging Mitochondria in Living Cells with Two-Photon Fluorescence Microscopy .2011 ,21 (2):497

(146)刘鑫. A Series of Carbazole Cationic Compounds with Large Two-Photon Absorption Cross Sections for Imaging Mitochondria in Living Cells with Two-Photon Fluorescence Microscopy .J Fluoresc .2011 ,21 (2):497

(147)刘鑫. A Series of Carbazole Cationic Compounds with Large Two-Photon Absorption Cross Sections for Imaging Mitochondria in Living Cells with Two-Photon Fluorescence Microscopy .J Fluoresc .2011 ,21 (2):497

(148)于晓强. A 2,7-carbazole-based dicationic salt for fluorescence detection of nucleicacids and two-photon fluorescence imaging of RNA in nucleoli and cytoplasm .Organic & Biomolecular Chemistry .2011 ,9 (0):3615

(149)于晓强. A 2,7-carbazole-based dicationic salt for fluorescence detection of nucleicacids and two-photon fluorescence imaging of RNA in nucleoli and cytoplasm .Organic & Biomolecular Chemistry .2011 ,9 (0):3615

(150)于晓强. A Series of Carbazole Cationic Compounds with Large Two-Photon Absorption Cross Sections for Imaging Mitochondria in Living Cells with Two-Photon Fluorescence Microscopy .J FLUORESC .2011 ,21 (0):497

(151)于晓强. A Series of Carbazole Cationic Compounds with Large Two-Photon Absorption Cross Sections for Imaging Mitochondria in Living Cells with Two-Photon Fluorescence Microscopy .J FLUORESC .2011 ,21 (0):497

(152)于晓强. Carbazole tricationic salt: A novel potential two-photon fluorescent DNA probe for nucleic imaging of cells .Chinese science bulletin .2010 ,55 (32):3661

(153)于晓强. Carbazole tricationic salt: A novel potential two-photon fluorescent DNA probe for nucleic imaging of cells .Chinese science bulletin .2010 ,55 (32):3661

(154)于晓强. Efficient Two-Photon Excited Amplified Spontaneous Emission from Organic Single Crystals .chemphyschem .2010 ,11 (0):1871

(155)于晓强. Efficient Two-Photon Excited Amplified Spontaneous Emission from Organic Single Crystals .chemphyschem .2010 ,11 (0):1871

(156)于晓强. 双阳离子咔唑衍生物与DNA作用的光谱研究 .《高等学校化学学报》 .2010 ,31 (9):1860

(157)于晓强. 双阳离子咔唑衍生物与DNA作用的光谱研究 .《高等学校化学学报》 .2010 ,31 (9):1860

(158)于晓强. Two-photon fluorescence imaging of DNA in living plant turbid tissue with carbazole dicationic salt .Organic & Biomolecular Chemistry .2010 ,8 (0):4582

(159)于晓强. Two-photon fluorescence imaging of DNA in living plant turbid tissue with carbazole dicationic salt .Organic & Biomolecular Chemistry .2010 ,8 (0):4582

(160)于晓强. 用于细胞核成像的2，7-BHVC双光子荧光探针 .《高等学校化学学报》 .2010 ,31 (6):1075

(161)于晓强. 用于细胞核成像的2，7-BHVC双光子荧光探针 .《高等学校化学学报》 .2010 ,31 (6):1075

(162)贾鹏飞. 2,7-BHVC，用于细胞核成像的2,7-BHVC 双光子荧光探针 .高等学校化学学报 .2010 ,31 (6):1075

(163)贾鹏飞. 2,7-BHVC，用于细胞核成像的2,7-BHVC 双光子荧光探针 .2010 ,31 (6):1075

(164)贾鹏飞. 2,7-BHVC，用于细胞核成像的2,7-BHVC 双光子荧光探针 .2010 ,31 (6):1075

(165)贾鹏飞. 2,7-BHVC，用于细胞核成像的2,7-BHVC 双光子荧光探针 .高等学校化学学报 .2010 ,31 (6):1075

(166)于晓强. Synthesis and nonlinear optical properties of several new two-photon photopolymerization initiators about dibenzothiophene derivatives .Synthetic Metals .2009 ,159 (0):2491

(167)于晓强. Synthesis and nonlinear optical properties of several new two-photon photopolymerization initiators about dibenzothiophene derivatives .Synthetic Metals .2009 ,159 (0):2491

(168)刘鑫. 一种新型的用于细胞核成像的双光子荧光探针 .2009 ,30 (3):465

(169)刘鑫. 一种新型的用于细胞核成像的双光子荧光探针 .2009 ,30 (3):465

(170)刘鑫. 一种新型的用于细胞核成像的双光子荧光探针 .高等学校化学学报 .2009 ,30 (3):465

(171)刘鑫. 一种新型的用于细胞核成像的双光子荧光探针 .高等学校化学学报 .2009 ,30 (3):465

(172)于晓强. 一种用于细胞核成像的荧光探针 .《高等学校化学学报》 .2009 ,30 (3):465

(173)于晓强. 一种用于细胞核成像的荧光探针 .《高等学校化学学报》 .2009 ,30 (3):465

(174)于晓强. 双光子生物荧光显微技术中的探针问题（综述） .大学化学 .2008 ,23 :1

(175)于晓强. 双光子生物荧光显微技术中的探针问题（综述） .2008 ,23 :1

(176)于晓强. 双光子生物荧光显微技术中的探针问题（综述） .大学化学 .2008 ,23 :1

(177)于晓强. Synthesis and nonlinear optical properties of two three-branched two-photon polymerization initiators .Synthetic Metals .2008 ,158 (21-24):964

(178)于晓强. Synthesis and nonlinear optical properties of two three-branched two-photon polymerization initiators .Synthetic Metals .2008 ,158 (21-24):964

(179)于晓强. Polymer waveguide grating fabricated by two-photon initiated photopolymerization and its application as an input coupler .Optical Materials .2008 ,30 (6):935

(180)于晓强. Polymer waveguide grating fabricated by two-photon initiated photopolymerization and its application as an input coupler .Optical Materials .2008 ,30 (6):935

(181)于晓强. The fabrication of index-modulated grating coupler in a polymeric waveguide using two-photon initiated photopolymerization .Thin Solid Films .2008 ,516 (6):1214

(182)于晓强. The fabrication of index-modulated grating coupler in a polymeric waveguide using two-photon initiated photopolymerization .Thin Solid Films .2008 ,516 (6):1214

(183)于晓强. 9-Ethyl-3,6-diformyl-9H-carbazole .ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE RE .2008 ,64 (0):o1293

(184)于晓强. 9-Ethyl-3,6-diformyl-9H-carbazole .ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE RE .2008 ,64 (0):o1293

Patents

1. 一种利用荧光图像显示细胞膜电位两种状态的荧光探针及其应用

2. 一种快速显示细胞膜电位正常状态与近零状态的荧光探针及其应用

3. 一种能双色同时成像细胞核和线粒体的pH敏感型荧光探针

4. 一种利用核仁形态变化快速区分癌与正常组织的RNA荧光探针

5. 一组用于同时显示活细胞中细胞核构造与细胞整体形态的荧光探针

6. 一种超高选择性且具两亲性的脂滴荧光探针及其应用

7. 一种基于分子转子的用于成像组织中细胞膜的双光子深红发射的荧光探针

8. 一种转子型的双红线粒体荧光探针及其应用

9. 一种具有大双光子荧光活性截面的膜通透性染料及其应用

10. 一种具有大双光子荧光活性截面的膜通透性染料及其应用

11. 一种转子型的双红线粒体荧光探针及其应用

12. 一种具有大双光子荧光活性截面的膜通透性染料及其应用

13. 一种单、双光子线粒体荧光探针及其应用

14. 一种用于活细胞中RNA和核仁成像的吡咯吡啶盐类荧光探针

15. 一种用于活细胞中RNA和核仁成像的吲哚吡啶盐类荧光探针

16. 一种单、双光子酸性细胞器荧光探针及其应用

17. 一种单、双光子半胱氨酸荧光探针及其应用

18. 一种单、双光子半胱氨酸荧光探针及其应用

19. 阳离子咔唑类化合物及其作为双光子核酸荧光探针的应用

20. 一种用于电致发光器件的红色荧光材料及制备方法

Research Projects

1. 分子探针荧光病理成像诊断常见恶性肿瘤, 2024-01-01-2026-12-31

2. 组合核酸荧光探针快速成像术中病理组织的结构适配与分子设计原理, 2023-07-28-2025-12-31

3. 基于荧光分子探针的肿瘤术中快速病理诊断新技术, 2022-09-30-2024-12-31

4. 组合荧光探针快速精准染色人体肿瘤组织核酸的分子机制与设计原理, 2021-11-24-2022-12-31

5. 高发恶性肿瘤诊治新技术研究-快速、精准、数字化诊断消化系常见恶性肿瘤病理系统研发, 2021-06-01-2022-12-31

6. 精准生物成像的双光子荧光探针的开发及产业化, 2021-01-01-2025-04-18

7. 双光子荧光光谱采集与显微成像系统的开发及产业化, 2021-01-01-2025-04-18

8. 基于细胞膜中磷脂排列特征设计荧光探针观测活细胞脂筏形态变化, 2021-01-01-2023-12-31

9. 能够实时长程追踪线粒体的长烷基链非反应型荧光探针, 2020-09-18-2024-12-31

10. 聚集/单体型同分子双靶标荧光探针：原位同时分辨活细胞质膜中两种超微结构, 2017-08-17-2021-12-31

11. 基于荧光分子探针与光学切片成像的肿瘤病理快速诊断技术, 2017-08-01-2019-07-31

12. 水样中有机污染物的双光子光谱检测技术, 2017-05-27-2018-05-27

13. 半胱氨酸及同型半胱氨酸高选择性双光子荧光探针及其在活细胞成像中的应用, 2012-08-17-2016-12-31

14. 双光子核酸荧光探针的研制及其在细胞成像中的应用（8）, 2012-07-31-2015-07-31

15. 双光子DNA荧光探针的研制, 2009-11-15-2015-11-15

16. 光波段具有负折射特性的特殊周期介质结构的研究, 2007-10-10-2009-12-30

17. 双生物光学窗口的水溶性双光子荧光材料研究及相关核酸探针的探索, 2007-01-01-2009-12-31

18. 光波段具有负折射特性的特殊周期介质结构的研究, 2004-09-01-2008-09-30

19. 聚合物型三维光子晶体, 2004-01-01-2007-01-01

20. 聚合物型三维光子晶体的激光微加工和微型光学器件的研究, 2003-01-30-2005-12-30