1. Li, Longfei; Yang, Shuo; Xu, Zhongyun; Li, Shengxiao; Jiang, Jie; Zhang, Yong-Qiang*

Dinuclear Titanium(III)-Catalyzed Radical-Type Kinetic Resolution of Epoxides for Enantioselective Synthesis of cis-Glycidic Esters

J. Am. Chem. Soc.  2024, Accepted.

The doctoral student Longfei Li developed the radical-Type Kinetic Resolution of Epoxides.

2. Shen, Jian; Xu, Zhongyun; Yang, Shuo; Li, Shengxiao; Jiang, Jie;* Zhang, Yong-Qiang*

 

Quaternary Stereocenters via Catalytic Enantioconvergent Allylation of Epoxides

 

J. Am. Chem. Soc. 2023, 145,  21122-21131.

The second doctoral student Jian Shen developed the first example of highly regio- and enantioselective allylation of epoxides.

3. Li, Shengxiao; Zhu, Hui; Li, Longfei; Chen, Wanjiao; Jiang, Jie; Qu, Zheng-Wang;* Grimme, Stefan; Zhang, Yong-Qiang*

 

A Nuclearity-Dependent Enantiodivergent Epoxide Opening via Enthalpy-Controlled Mononuclear and Entropy-Controlled Dinuclear (Salen) 

Titanium Catalysis

 

Angew. Chem. Int. Ed. 2023, 62, e202309525.

 

The first doctoral student Shengxiao Li developed the first nuclearity-dependent enantiodivergent catalysis.

4. Li, Longfei; Chen, Wanjiao; Xu, Zhongyun; Jiang, Jie; Zhang, Yong-Qiang*

 

Enantioselective Synthesis of (R)-Tiagabine via Asymmetric Hydrogen Atom Transfer Protocol

 

Synthesis. 2023, 55, 2005-2010.

Highlighted in the Thieme news section Apr. 6, 2023.

 

The second master student Longfei Li realized asymmetric synthesis of (R)-tiagabine using our asymmetric catalytic HAT protocol.

5. Xu, Zhongyun; Shen, Jian; Li, Longfei,; Chen, Wanjiao; Li, Shengxiao; Jiang, Jie; Zhang, Yong-Qiang*

 

(Salen)Titanium-Catalyzed Asymmetric Hydrogen Atom Transfer for Epoxides Reduction

 

Angew. Chem. Int. Ed. 2022, 61, e202214111.

Highlighted by Org. Chem. Portal July 17, 2023.

The first master student Zhongyun Xu realized the first example of catalytic asymmetric reduction of epoxides.

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Selected Before SDU:

1. Zhang, Y. –Q.; Bohle. F.; Bleith, R.; Schnakenburg, G.; Grimme, S.*; Gansäuer, A.*. Synthesis of 1,3-amino alcohols by hydroxyl-directed aziridination 

and aziridine hydrosilylation.

Angew. Chem. Int. Ed. 2018, 57, 13528-13532.

2. Zhang, Y. -Q.; Vogelsang, E.; Qu, Z.-W.; Grimme, S.; Gansäuer, A.*. Titanocene-catalyzed radical opening of N-acylated aziridines.

Angew. Chem. Int. Ed. 2017, 56, 12654-12657.

3. Zhang, Y. -Q.; Poppel, C.; Panfilova, A.; Bohle, F.; Gansäuer, A.*. SN2 at tertiary carbon centers in epoxides.

Angew. Chem. Int. Ed. 2017, 56, 9851-9854.

4. Zhang, Y. -Q.; Jakoby, V.; Stainer, K.; Schmer, A.; Klare, S.; Bauer, M.; Grimme, S.; Cuerva, J. M.; Gansäuer, A.*. Amide-substituted titanocenes in 

HAT-catalysis.

Angew. Chem. Int. Ed. 2016, 55, 1523-1526.

5. Zhang, Y. -Q.; Funken, N.; Winterscheid, P.; Gansäuer, A.* Hydroxy-directed, fluoride-catalyzed epoxide Hydrosilylation for the synthesis of 1,4-

Diols.

Angew. Chem. Int. Ed. 2015, 54, 6931-6934.

6. Zhang, Y. -Q.; Yuan, Y. –A.; Liu, G. –S.; Xu, H.*. Iron(II)-catalyzed intramolecular asymmetric aminohydroxylation of indoles.

Org. Lett. 2013, 15, 3910-3913.

7. Zhang, Y. -Q.#; Liu, J. –D.#; Xu, H.*. Copper(II)-catalyzed trifluoromethylation of N-aryl imines. (# The two authors contributed equally)

Org. Biomol. Chem. 2013, 11, 6242-6245.

8. Zhang, Y. -Q.; Zhu, D. -Y.; Li, B. -S.; Tu, Y. -Q.*; Liu, J. -X.; Lu, Y.; Wang,S. –H.. Palladim-Catalyzed cascade process to construct 1,2,5-trisubstituted 

pyrroles.

J. Org. Chem. 2012, 77, 4167-4170.

9. Zhang, Y. -Q.; Zhu, D. -Y.; Jiao, Z. -W.; Li, B. -S.; Zhang, F. -M.; Tu, Y. -Q.*; Bi, Z.. Regiodivergent annulations of alkynyl indoles to construct spiro-

pseudoindoxyl and tetrahydro-β-carbolines.

Org. Lett. 2011, 13, 3458-3461.

10. Zhang, Y. -Q.; Chen, Z. -H.; Tu, Y. -Q.*; Fan, C. -A.; Zhang, F. -M.; Wang, A. -X.; Yuan, D. -Y.. Gold-catalyzed reaction of enynols by a dimerization-

fragmentation process: An expeditious assembly of enyne molecular architecture.

Chem. Commun. 2009, 45, 2706-2708.