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个人信息Personal Information
教授 博士生导师 硕士生导师
性别：男
毕业院校：山东大学
学历：研究生(博士)毕业
学位：医学博士学位
在职信息：在职
所在单位：药学院
入职时间：2013-02-28
联系方式：zhangyingjie@sdu.edu.cn
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- [121] 徐文方 and 张颖杰. Discovery of the First N-hydroxycinnamamide-based Histone Deacetylase 1/3 Dual Inhibitors with Potent Oral Antitumor Activity. J. Med. Chem., 2014.
- [122] 张颖杰. Developments of Polo-like Kinase 1 (Plk1) Inhibitors as Anti-Cancer Agents. Mini. Rev. Med. Chem., 13, 2014, 2013.
- [123] 张颖杰. Design and synthesis of a tetrahydroisoquinoline-based hydroxamate derivative (ZYJ-34v), an oral active histone deacetylase inhibitor with potent antitumor activity.. Chem. Biol. Drug Des., 82, 125, 2013.
- [124] 张颖杰. Discovery of a pair of diastereomers as potent HDACs inhibitors: determination of absolute configuration, biological activity comparison and computational study.. Rsc Adv., 3, 21106, 2013.
- [125] 张颖杰. Development of N-Hydroxycinnamamide-Based Histone Deacetylase Inhibitors with an Indole-Containing Cap Group.. ACS Med. Chem. Lett., 4, 235, 2013.
- [126] 张颖杰. Synthesis and biological evaluation of N-(4-hydroxy-3-mercaptonaphthalen-1-yl)amides as inhibitors of angiogenesis andtumor growth.. Eur. J. Med. Chem., 64, 377, 2013.
- [127] 张颖杰. Discovery of 4-amino-2-(thio)phenol derivatives as novel protein kinase and angiogenesis inhibitors for the treatment of cancer: Synthesis and biological evaluation. Part II.. Eur. J. Med. Chem., 69, 191, 2013.
- [128] 张颖杰. Discovery of a fluorescent probe with HDAC6 selective inhibition. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 141, 596, 2017.
- [129] 徐文方 , 张颖杰 and 曹江营. Novel leucine ureido derivatives as aminopeptidase N inhibitors using click chemistry. Bioorganic & medicinal chemistry, 26, 3145, 2018.
- [130] 张颖杰 , 徐文方 and 江余祺. Synthesis and biological characterization of ubenimex-fluorouracil conjugates for anti-cancer therapy. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 143, 334, 2018.
- [131] 张颖杰 , 徐文方 and 曹江营. Design, Synthesis, and Biological Evaluation of Pyrazoline-Based Hydroxamic Acid Derivatives as AminopeptidaseN (APN) Inhibitors. CHEMMEDCHEM, 13, 431, 2018.